Otay Mesa West Travel Guide
Tourist Guide
Visit Otay Mesa West
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's entertainment choices and fascinating museums.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Mission Bay
Mission Bay is San Diego’s vast and beautiful outdoor playground with great weather and calm waters that seem made for watersports.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Activities
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Whale Watching & Dolphin Cruise
San Diego: Luggage Storage in Marina
City Cruises San Diego: Whale & Dolphin Watching Adventure
Our pick of the best Otay Mesa West Hotel Deals
Hard Rock Hotel San Diego
Room was very clean and luxurious
Reviewed on 5 Feb 2026
Paradise Point Resort & Spa
The staff were absolutely incredible!! We loved the hotel, restaurants and amenities!
Reviewed on 7 Feb 2026
The DEXTRO Little Italy, BW Premier Collection
Totally better than i expected!!
Reviewed on 6 Feb 2026
The Sofia Hotel
Great location and very clean!
Reviewed on 7 Feb 2026
The Dana on Mission Bay
I would like to take a moment to recognize the wonderful staff members who made our recent stay so special. From the moment we walked through the door, the lady who checked us in was absolutely amazing. She was so kind, patient, and welcoming that she instantly made me smile. We stay at this hotel ...
Reviewed on 7 Feb 2026
Hampton Inn & Suites by Hilton San Diego SeaWorld
room were very comfortable and me and my family enjoyed the breakfast included. My only problem was the bathroom door not closing right and having to leave it open do it did not slam shut.
Reviewed on 4 Feb 2026
Other neighbourhoods around Otay Mesa West
East Village
Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
