
Otay Mesa West Holidays
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Your Otay Mesa West Holiday
Otay Mesa West is beckoning! Whatever type of adventure you're planning, you can discover more of this neighbourhood with an Otay Mesa West holiday package. Plan enough time on your itinerary to see leading nearby sights such as Kaiser Permanente Otay Mesa Medical Offices during your trip to Otay Mesa West. Whatever your dream Otay Mesa West holiday may look like, you can turn it into reality with Expedia.
Our guide on where to stay in Otay Mesa West

Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Our pick of the best Otay Mesa West Hotel Deals

Bay Club Hotel & Marina
The room was great! Loved the view! Staff was so nice! Room service does a great job at making virgin piña colada’s! Great location! only one complaint is it’s a little loud but it quiet down after 10!
Reviewed on 7 Dec 2025

Legacy Resort Hotel & Spa
All was great
Reviewed on 8 Dec 2025

The DEXTRO Little Italy, BW Premier Collection
Great little boutique hotel ! Friendly staff as well
Reviewed on 7 Dec 2025
Frequently asked questions
Discover the most popular places to visit in Otay Mesa West

San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.

Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.

Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Activities

San Diego Old Town Trolley Hop-On Hop-Off Tour
















