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Our top choices for Panacea hotels

The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (142 reviews)
"The room was clean. the ac was great"
United States
Elliot
The Panacea Motel

The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
9.0 out of 10, Wonderful, (2 reviews)
"Clean room, older property but had old Florida charm."
United States
Deirdre
The price is AU$140
includes taxes & fees
28 Jan - 29 Jan
The Old Carrabelle Hotel

The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1,007 reviews)
"Great old Florida Lodge Beautiful grounds and springs"
United States
Ed
The Lodge at Wakulla Springs

St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (375 reviews)
"Great size room and good food"
United Kingdom
Edi
The price is AU$260
includes taxes & fees
2 Feb - 3 Feb
St James Bay Golf & Pickleball Resort

Franklin Inn

Franklin Inn
2.0 star property
Carrabelle
7.8 out of 10, Good, (457 reviews)
"JJ was great great location clean room comfortable bed and good value. "
United States
Crystal
The price is AU$124
includes taxes & fees
5 Feb - 6 Feb
Franklin Inn

The Moorings Hotel and Marina

The Moorings Hotel and Marina
2.5 star property
Carrabelle
8.4 out of 10, Very good, (39 reviews)
"Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!"
United States
Cheryl
The price is AU$211
includes taxes & fees
4 Feb - 5 Feb
The Moorings Hotel and Marina

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (951 reviews)
"Breakfast last was super nice and helpful. Room was clean and comfortable. Only issue was when we returned after the day out room service cleaned the room but left out room door open. "
United States
Wendy
The price is AU$184
includes taxes & fees
18 Feb - 19 Feb
Best Western Wakulla Inn & Suites

Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1,001 reviews)
"Enjoyed our stay and would definitely stay again!"
United States
Corey
The price is AU$186
includes taxes & fees
4 Feb - 5 Feb
Wildwood Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Panacea attractions

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

Sunset over a lake at Panacea, northern Florida, USA | NONE |

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Frequently asked questions

Where is the best place to stay in Panacea?
Expedia customers give high marks to The Panacea Motel. See all available top hotels, or vacation rentals in Panacea.
What are some of the best holiday rentals that Panacea has to offer?
Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach: This highly rated holiday home rental in Panacea is located on the beach, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. It offers a garden, a selection of games and 1 hot tub so that you can immerse yourself in your holiday. Other favourite homes for rent in Panacea are Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes + and NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!. See all vacation rentals in Panacea.
If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
What's the best dog-friendly place to stay in Panacea?
The Panacea Motel is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What are some accommodation options with pools in Panacea?
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front: Offers complimentary wireless Internet access, a pool and kitchens. View all hotels with pools in Panacea.
How is it to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors will definitely appreciate the beaches and seafood restaurants. The relaxing and secluded setting also entices those visiting the city. In Panacea, there are 211 hotels and other accommodation options to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach and Bald Point State Park. Dolphin viewing is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your itinerary are Otter Lake and Wilson Beach. Take a look at what more there is to see and do in Expedia's Panacea guide.
What's the seasonal weather in Panacea?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. The rainiest months in Panacea are August, July, June and September, with each month seeing an average of 201 mm of rainfall.

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