Photo by Jen - Nealys On Wheels

Business Hotels & Resorts in North Central Florida from AU$136

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on North Central Florida Business Hotels

Tonight
3 Dec - 4 Dec
Tomorrow
4 Dec - 5 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Best North Central Florida Business Hotels

Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
Alachua
9.4 out of 10, Exceptional, (1002)
"Staff was great and the location is perfect ! "
United States
JAY
The price is AU$193
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Lobby
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1138)
"Nice staff, good breakfast, confy beds and pillows, good location"
United States
Gema
The price is AU$144
includes taxes & fees
18 Dec - 19 Dec
Comfort Suites Gainesville near University
Lobby
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

2.5 star property
Lake City
9.4 out of 10, Exceptional, (1000)
"It was a great stay "
United States
Miranda
The price is AU$153
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Lake City
Exterior
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

3.0 star property
Gainesville
9.0 out of 10, Wonderful, (1611)
"Great stay - Bed was comfortable, Room was clean and quiet! "
United States
Maggie
The price is AU$156
includes taxes & fees
28 Dec - 29 Dec
Country Inn & Suites by Radisson, Gainesville, FL
Exterior
Comfort Suites Dunnellon near Rainbow Springs

Comfort Suites Dunnellon near Rainbow Springs

2.5 star property
Dunnellon
9.0 out of 10, Wonderful, (1002)
"Very good place to stay the night in comfort. "
United States
Juan
The price is AU$136
includes taxes & fees
14 Dec - 15 Dec
Comfort Suites Dunnellon near Rainbow Springs
View from property
Guy Harvey Resort on St Augustine Beach

Guy Harvey Resort on St Augustine Beach

3.0 star property
St. Augustine
8.8 out of 10, Excellent, (2790)
"great location"
United States
Barry
The price is AU$201
includes taxes & fees
4 Dec - 5 Dec
Guy Harvey Resort on St Augustine Beach
Exterior
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 star property
Lake City
9.2 out of 10, Wonderful, (1000)
"Great place for a restful night when traveling. "
United States
Peggy
The price is AU$178
includes taxes & fees
7 Dec - 8 Dec
Tru by Hilton Lake City
Exterior
PaddleTail Waterfront Lodge, Trademark Collection by Wyndham

PaddleTail Waterfront Lodge, Trademark Collection by Wyndham

2.5 star property
Crystal River
8.8 out of 10, Excellent, (1321)
"Great hotel, fabulous location for both bars and sightseeing tours. Will be back again. Great breakfast too"
United Kingdom
caroline
The price is AU$201
includes taxes & fees
7 Dec - 8 Dec
PaddleTail Waterfront Lodge, Trademark Collection by Wyndham
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

2.5 star property
Alachua
9.4 out of 10, Exceptional, (471)
"Staff very helpful- clean updated facility. "
United States
bethany
The price is AU$163
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites Alachua I-75
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

2.5 star property
Lake City
9.2 out of 10, Wonderful, (1020)
"It was perfect, we got in super late an was met with a quick check in an a great breakfast the next day"
United States
Aurora
The price is AU$142
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top North Central Florida Hotel Reviews

Quality Inn & Suites Ocala I-75

Quality Inn & Suites Ocala I-75

10/10 Excellent
"We did not use the breakfast bar. Parking was Ok, we just couldn't park in front of our room. We had to walk to the backside of the hotel and there were no carts to transport our luggage. The shades on the windows do not keep the night light out of the room and it was hard to sleep because of to much light coming through from the walkway. "
Gary 1-night trip
Posted 10 days ago
Quality Inn & Suites Ocala I-75

Frequently asked questions

How much do business-friendly hotels in North Central Florida cost?
You'll pay between AU$136 and AU$201 per night for business-friendly hotels in North Central Florida. Awesome deals on stays that cater to work-related guests are a few clicks away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in North Central Florida?
When your next meeting or networking event takes you someplace in North Central Florida, you'll have 89 business-friendly hotels to choose from.
What is there to do in North Central Florida near my business-friendly hotel?
The most important accessory for your North Central Florida business journey is a good itinerary for when you have some spare time! Easy Street Family Fun Centre, Ocala Downtown Square and Hampton Aquatic Fun Centre are some of the leading things to do if you're off to Ocala. Gainesville is also packed with big-name attractions, such as Florida Museum of Natural History, University of Florida Bat Houses and Hippodrome State Theatre.

Explore a world of travel with Expedia