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Our top choices for La Cruceña hotels

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (347)
"Great spacious property with nice pool!"
United States
Douglas
The price is AU$193
4 Jan - 5 Jan 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (94)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
United States
Andrew
Apart Hotel Premium Suites Santa Cruz

Surbackpackers

Surbackpackers
3.0 star property
Santa Cruz
The price is AU$37
1 Jan - 2 Jan 2026
Surbackpackers

Posada Express Fast Check

Posada Express Fast Check
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (2)
The price is AU$48
19 Jan - 20 Jan 2026
Posada Express Fast Check

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (332)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is AU$133
3 Jan - 4 Jan 2026
Sun Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (211)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is AU$166
3 Jan - 4 Jan 2026
Marriott Santa Cruz de la Sierra Hotel

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (105)
"Good price"
United States
Salem
Hotel G

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (78)
"Great Spot"
United States
Jose
The price is AU$58
29 Dec - 30 Dec
Ibis Santa Cruz DE LA Sierra

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (82)
"Good price, great hotel!"
United States
James
The price is AU$58
29 Dec - 30 Dec
Premium Suites Deluxe Aparthotel Equipetrol

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (124)
"The staff and property are second to none! "
United States
Cynthia
The price is AU$184
9 Jan - 10 Jan 2026
Hotel Cortez

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (409)
"The parrots. Unique"
United States
Juan P
The price is AU$269
4 Jan - 5 Jan 2026
Camino Real Hotel

Casa Por Temporadas

Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
United States
Cynthia
The price is AU$127
6 Jan - 7 Jan 2026
Casa Por Temporadas

Mirador del Cielo

Mirador del Cielo
3.0 star property
Santa Cruz
The price is AU$37
29 Dec - 30 Dec
Mirador del Cielo

Hotel Arenal

Hotel Arenal
3.5 star property
Santa Cruz
7.6 out of 10, Good, (59)
"Perfect hotel in a central location!"
United States
Max
The price is AU$92
27 Jan - 28 Jan 2026
Hotel Arenal

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (104)
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is AU$149
12 Jan - 13 Jan 2026
Novotel Santa Cruz De La Sierra

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (258)
"Nice hotel "
United States
Narciso Lorenzo
The price is AU$137
1 Jan - 2 Jan 2026
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (30)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is AU$52
8 Jan - 9 Jan 2026
Lido Hotel

Urban Suites

Urban Suites
3.0 star property
Santa Cruz
The price is AU$80
29 Dec - 30 Dec
Urban Suites

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.4 out of 10, Very good, (7)
"Perfect hotel"
Turkey
Yener
The price is AU$59
26 Jan - 27 Jan 2026
Equipetrol Suites Apart Hotel

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (146)
"Nice stay with good service "
United States
Jianyuan
The price is AU$147
29 Dec - 30 Dec
TRYP by Wyndham Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place for a stay in La Cruceña?
Located 14.5 mi (23.3 km) from the heart of La Cruceña, Ibis Santa Cruz DE LA Sierra is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Marriott Santa Cruz de la Sierra Hotel and Hotel Las Américas. See all available top hotels, or vacation rentals in La Cruceña.
What are some of the best holiday rentals that La Cruceña has to offer?
Cozy and independent. Downtown house JH.: This holiday home rental outside of La Cruceña is equipped with a patio, air conditioning and cable TV to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge and an oven. See all vacation rentals in La Cruceña.
If I need to cancel my hotel reservation in La Cruceña, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in La Cruceña.
What's it like to stay in La Cruceña?
Those travelling to La Cruceña will definitely enjoy the sights to see and things to do. There are 286 hotels and other accommodation options in the surrounding area. Find out more about La Cruceña.
What is there to see in La Cruceña?
Places to visit in the wider area include Cine Center, Plaza 24 de Septiembre and Ramon Tahuichi Aguilera Stadium. You'll also find Santa Cruz Zoo and Ventura Mall in the area. Take a look at what more there is to see and do in Expedia's La Cruceña guide.
What's the weather like in La Cruceña?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for La Cruceña is 1215 mm.

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