A rustic wooden interior with a table, a basket, and a painting on easels.

Adults Only & Resorts in James Island from AU$271

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on James Island Adults Only

Tonight
17 Sept - 18 Sept
Tomorrow
18 Sept - 19 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

Our top choices for James Island adults-only hotels

1. The Jasmine House

The Jasmine House
Charleston Historic District
United States
Haley
AU$360
includes taxes & fees
4 Oct - 5 Oct
The Jasmine House

2. Regatta Inn Folly Beach

Regatta Inn Folly Beach
Folly Beach
United States
Emily
AU$358
includes taxes & fees
20 Sept - 21 Sept
Regatta Inn Folly Beach

3. Bright Historic Charleston Luxury Condo

Bright Historic Charleston Luxury Condo
Downtown Charleston
United States
Oleg T.
AU$647
includes taxes & fees
24 Sept - 25 Sept
Bright Historic Charleston Luxury Condo

4. BIJOU, Boutique Inn

BIJOU, Boutique Inn
Charleston Historic District
United States
Mollie
AU$403
includes taxes & fees
20 Sept - 21 Sept
BIJOU, Boutique Inn

5. 86 Cannon Charleston - Adults Only

86 Cannon Charleston - Adults Only
Downtown Charleston
United States
Stephanie
AU$812
includes taxes & fees
23 Sept - 24 Sept
86 Cannon Charleston - Adults Only

6. Water's Edge Inn - Adults Only

Water's Edge Inn - Adults Only
Folly Beach
United States
Karleen
AU$271
includes taxes & fees
29 Sept - 30 Sept
Water's Edge Inn - Adults Only
View all properties

Top James Island Hotel Reviews

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

8/10 Good
"This is the perfect place for a nice getaway! It’s tucked away nicely and easily accessible to what you may have left at home."
Dorenda 2-night trip
Posted 3 days ago
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Explore a world of travel with Expedia