Photo by Delen Wong

Search Isla Santa María hotels

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top hotels and accommodation in Isla Santa María

Hotel Cucuve

4.0 star property
10.0 out of 10, Exceptional, (259)
"We had an excellent stay at Hotel Cucuve. The property was very clean and well maintained, and the staff were consistently friendly, professional, and helpful throughout our visit. The breakfast was very nice. I would not hesitate to recommend this hotel to others."
The price is AU$325
15 Sept - 16 Sept
Hotel Cucuve

Natura Gardens Galápagos Hotel

3.0 star property
7.6 out of 10, Good, (4)
The price is AU$203
15 Sept - 16 Sept
Natura Gardens Galápagos Hotel

Hostal Miconia

2.5 star property
6.0 out of 10, (40)
"Mean owner"
Hostal Miconia

Twin Hotel Galapagos

3.0 star property
8.4 out of 10, Very good, (42)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
The price is AU$101
18 Sept - 19 Sept
Twin Hotel Galapagos

Hotel La Casa de Judy

3.0 star property
9.0 out of 10, Wonderful, (157)
"The staff was nice and friendly. They were accommodating to our needs. They offered helpful suggestions to places and food locations nearby. Recommend coming here again."
The price is AU$137
17 Sept - 18 Sept
Hotel La Casa de Judy

Fernandina Hotel & Spa Galápagos

3.0 star property
9.4 out of 10, Exceptional, (18)
"Great service awesome hotel and beautiful island "
The price is AU$170
30 Sept - 1 Oct
Fernandina Hotel & Spa Galápagos

Posada del Mar

3.0 star property
9.8 out of 10, Exceptional, (198)
"Good location"
The price is AU$104
27 Sept - 28 Sept
Posada del Mar

Hotel Santa Fe

4.0 star property
9.6 out of 10, Exceptional, (14)
"Beautiful hotel, with amazing staff, and great location "
The price is AU$307
15 Sept - 16 Sept
Hotel Santa Fe

Hostal España

3.0 star property
7.6 out of 10, Good, (119)
"Perfect location; walkable and lots of options. Will stay again."
Hostal España

Capitan Max B&B

3.0 star property
9.8 out of 10, Exceptional, (180)
"The place is great and the host is very kind!"
Capitan Max B&B

Plaza Luna Suites

3.0 star property
9.8 out of 10, Exceptional, (27)
"This hotel great location and employees are awesome, wonderful, nice and very professional friendly. This hotel is a gem in Puerto Ayora "
Plaza Luna Suites

Hotel Fiesta

3.5 star property
9.0 out of 10, Wonderful, (365)
"Very nice place and the very large hot tub was nice to relax in after the day."
The price is AU$234
15 Sept - 16 Sept
Hotel Fiesta

Blu Galapagos Sustainable Waterfront Lodge

4.0 star property
8.8 out of 10, Excellent, (115)
"We had a great stay at Blu Galapagos. Loved the location and our room was perfect - Great view, well maintained and had a king bed. Even if the description says queen bed and the picture looks like a king, you can trust the picture. Morning breakfast with iguanas and seals, and all day Galapagos coffee availability made this stay special. "
The price is AU$285
28 Sept - 29 Sept
Blu Galapagos Sustainable Waterfront Lodge

Angermeyer Waterfront Inn

3.5 star property
9.4 out of 10, Exceptional, (121)
"Beautiful view and very friendly staff. You do have to take a water taxi ($1 and operates 24/7) to the main part of downtown Santa Cruz but the view is worth it! Also it’s across from The Point by Midoro which as an amazing view and food. I would stay there again! "
The price is AU$431
15 Sept - 16 Sept
Angermeyer Waterfront Inn

Hotel Ninfa

3.5 star property
8.4 out of 10, Very good, (209)
"Great hotel to use as your base while exploring Galapagos, and a lovely pool, hot tub and bar to come home to at the end of the day"
Hotel Ninfa

Ikala Galapagos Hotel

4.0 star property
9.6 out of 10, Exceptional, (121)
"Centrally located with lots of choices to shop and eat. A block away from The Port and plenty of taxis available. The Staff was great and their breakfasts in the morning are incredible! WiFi was a little spotty but that’s the only thing I’d change. They even packed us little snack bags for our airport run!! "
The price is AU$364
15 Sept - 16 Sept
Ikala Galapagos Hotel

Lava House Hostal

3.0 star property
9.2 out of 10, Wonderful, (50)
"Had a great stay at Lava House. Clean and quiet, a small paradise in the middle of Santa Cruz. "
Lava House Hostal

Lonesome George Ecolodge

2.5 star property
9.0 out of 10, Wonderful, (22)
"Very comfortable stay at Victors beautiful property. Great central location in Puerto Ayora"
The price is AU$150
15 Sept - 16 Sept
Lonesome George Ecolodge

Hostal Casa Eden Galapagos

3.0 star property
8.8 out of 10, Excellent, (6)
"Great little room... walking distance from the tourist strip. Clean and comfortable. Manager was not on site when I arrived, and had to call her. The showers were pretty average and I had to request the hot water be put on. Air con worked really well. It's a budget style hostel/hotel. I'd stay there again, but with lower expectations."
The price is AU$110
15 Sept - 16 Sept
Hostal Casa Eden Galapagos

White House Galapagos

2.5 star property
9.0 out of 10, Wonderful, (95)
"Better than I expected. Great value "
White House Galapagos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near top Isla Santa María attractions

Post Office Bay
Post Office Bay

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.

Learn more about Isla Santa María

Explore attractions like Galápagos National Park and Post Office Bay as you discover things to see and do in Isla Santa María.

Top Isla Santa María Hotel Reviews

More cheap accommodation in Isla Santa María

More cheap accommodation in Isla Santa María

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Where is the best place for a stay in Isla Santa María?

Located 38.3 mi (61.7 km) from the heart of Isla Santa María, Hotel Fiesta is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Hotel el descanso del Guia and Hotel Cucuve. See all available top hotels, or vacation rentals in Isla Santa María.

What are some of the best holiday rentals that Isla Santa María has to offer?

Villa Galapagos: This holiday home rental outside of Isla Santa María is located near the beach, and offers a private garden, air conditioning and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Isla Santa María.

If I need to cancel my hotel reservation in Isla Santa María, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Isla Santa María.

What is staying in Isla Santa María like?

Travellers to Isla Santa María will find plenty to explore and enjoy. There are 197 hotels and other accommodation options in the larger region. Find out more about Isla Santa María.

What is there to see in Isla Santa María?

Favourite places to visit include Galápagos National Park, Post Office Bay and Punta Suarez. Take a look at what more there is to see and do in Expedia's Isla Santa María guide.

What's the seasonal weather in Isla Santa María?

The hottest months are usually March and February, with an average temperature of 26°C, while the coldest months are September and October, with an average of 22°C. Average annual precipitation for Isla Santa María is 319 mm.