Name: Hotel el descanso del Guia
Rating: 8.8

Photo by Delen Wong

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Your Isla Santa María Holiday

Our Isla Santa María holiday packages give you the power to customise your own adventure. Tailor your journey to suit your interests and needs and make the most of your time in this fantastic city. Hoping to do a little sightseeing? Spend your days exploring popular attractions like Post Office Bay during your trip to Isla Santa María. No matter your travel plans or the size of your budget, putting together a tailored Isla Santa María holiday is a walk in the park with Expedia.

Isla Santa María Holiday

Isla Santa Marían Essential Information

Language	Spanish
Currency	U.S dollars
Local Welcome	¡Hola!
Local Goodbye	Adiós

Our pick of the best Isla Santa María Hotel Deals

Hotel Fiesta

Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos

Fully refundableReserve now, pay when you stay

AU$220

13 Mar - 14 Mar

9/10 Wonderful! (395 reviews)

Good reception staff. Good breakfast

Reviewed on 20 Feb 2026

Maidith Galapagos Inn

Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos

AU$204

26 Mar - 27 Mar

10/10 Exceptional! (117 reviews)

The hotel is just like the pictures. It’s close to the Darwin Center and we were able to walk everywhere. The owners could not do enough for us and SO kind and friendly. The breakfast was unbelievable. There was fresh fruit everyday with yogurt and granola, juice, unlimited coffee and something homemade ...

Reviewed on 8 Mar 2026

Hotel el descanso del Guia

Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos

8.8/10 Excellent! (193 reviews)

The staff was amazing, so attentive and kind!

Reviewed on 25 Feb 2026

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See all 208 properties in Isla Santa María

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.