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Our top choices for Defiance hotels

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,001 reviews)
"Excellent place to stay!"
United States
Steven
The price is AU$118
includes taxes & fees
16 June - 17 June
Baymont by Wyndham Warrenton

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (1,003 reviews)
"Staff was helpful, area was easy tp navigate. Place was great for the price"
United States
Ryan
The price is AU$133
includes taxes & fees
16 June - 17 June
Quality Inn Foristell

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,335 reviews)
"Our room was clean and modern, the location was great for our weekend activity, and the breakfast was great. We would stay here again."
United States
Jamie
The price is AU$161
includes taxes & fees
7 June - 8 June
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.6 out of 10, Excellent, (143 reviews)
"Overall a good stay. Would stay there again."
United States
Roxanne
The price is AU$122
includes taxes & fees
6 July - 7 July
WoodSpring Suites St Peters-OFallon

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (653 reviews)
"Terrific staff very helpful manager"
United States
Dale
The price is AU$95
includes taxes & fees
17 June - 18 June
Super 8 by Wyndham Warrenton

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,006 reviews)
"Very impressed by friendliness of the staff The inside was clean and fresh, rooms were fresh and comfortable, breakfast was extraordinary great"
United States
RODNEY
The price is AU$147
includes taxes & fees
21 June - 22 June
Sleep Inn & Suites O'Fallon MO - Technology Drive

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (920 reviews)
"We always stay here when we are in town. Staff is always very friendly and the pet fee is only $20."
United States
Randy
The price is AU$240
includes taxes & fees
14 June - 15 June
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,010 reviews)
"Great location and clean hotel!"
United States
Admir
The price is AU$222
includes taxes & fees
5 July - 6 July
Drury Inn & Suites St. Louis St. Peters

Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1,003 reviews)
"Quiet and wood's surroundings nice place"
United States
Matthew
The price is AU$148
includes taxes & fees
9 June - 10 June
Comfort Inn & Suites St. Louis - O'Fallon

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,239 reviews)
"Clean room, good staff, breakfast OK."
United States
MARK
The price is AU$144
includes taxes & fees
7 June - 8 June
Wingate by Wyndham St. Louis/Fenton Route 66

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,001 reviews)
"The location was great. The breakfast was okay. The room was clean."
United States
Daniel
The price is AU$191
includes taxes & fees
21 June - 22 June
Hampton Inn St. Charles St. Peters

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (692 reviews)
"Very clean and staff were friendly. Breakfast was good and will definitely stay here again. "
United States
Rod
The price is AU$206
includes taxes & fees
17 June - 18 June
Best Western Plus Washington Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,651 reviews)
"Very nice hotel for the price! Would definitely stay there again in the future!"
United States
Lori
The price is AU$137
includes taxes & fees
22 June - 23 June
The Wildwood Hotel

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (317 reviews)
"Staff and breakfast were amazing!"
United States
Shilo
The price is AU$148
includes taxes & fees
5 July - 6 July
Best Western Plus Fenton

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very good, (1,005 reviews)
"Only needed a place to stay for the night and this was the perfect place. Very convenient from everywhere we wanted to go with a clean and comfortable room!"
United States
Kenzie
The price is AU$136
includes taxes & fees
25 June - 26 June
Super 8 by Wyndham St Charles

Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,005 reviews)
"Ample parking space and staff are good and accommodating "
United States
Aileen
The price is AU$144
includes taxes & fees
5 July - 6 July
Country Inn & Suites by Radisson, St. Peters, MO

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.4 out of 10, Exceptional, (411 reviews)
"Great stay. Easy and quick check in."
United States
John
The price is AU$192
includes taxes & fees
14 June - 15 June
Holiday Inn Express & Suites St Peters by IHG

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,006 reviews)
"Excellent breakfast and pet friendly is a huge plus "
United States
Elleigh
The price is AU$210
includes taxes & fees
5 July - 6 July
Drury Inn & Suites Southwest St. Louis

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,003 reviews)
"We had a great stay"
United States
Alexa
The price is AU$163
includes taxes & fees
5 July - 6 July
Comfort Suites St Charles - St Louis

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
St. Peters
6.2 out of 10, (1,000 reviews)
"Overall great experience, staff was friendly and very helpful. Made it a seamless experience from check in to check out."
United States
Chris
The price is AU$116
includes taxes & fees
21 June - 22 June
Days Inn by Wyndham St Peters/St Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

More cheap accommodation in Defiance

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and The Wildwood Hotel. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
Charming 3-bedroom house in delightful Ballwin and basement is not included: This holiday home rental outside of Defiance has air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. The Wildwood Hotel and Ameristar Casino Resort and Spa are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. A top sight in the area is Six Flags St. Louis. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at Matson Hill Park Trailhead, August A. Busch Memorial Conservation Area and Missouri River. Additionally, you'll find Six Flags St. Louis in the area. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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