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Top hotels and accommodation in Defiance

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
8.2 out of 10, Very good, (1033)
"Clean room and staff was great "
United States
Beth
The price is AU$151
includes taxes & fees
2 Nov - 3 Nov
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
The Wildwood Hotel
3.5 star property
9.2 out of 10, Wonderful, (1599)
"Perfect stay"
United States
Justin
The Wildwood Hotel
Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
8.0 out of 10, Very good, (1009)
"This was a very nice place to stay. Centrally located, very clean and quiet with a great breakfast!"
United States
Kirsti
The price is AU$155
includes taxes & fees
29 Oct - 30 Oct
Sonesta ES Suites St. Louis - Chesterfield
Super 8 by Wyndham Eureka/Six Flags Nearby
2.0 star property
7.0 out of 10, Good, (1010)
"Clean rooms fully stocked room with towels "
United States
Paul
The price is AU$109
includes taxes & fees
3 Nov - 4 Nov
Super 8 by Wyndham Eureka/Six Flags Nearby
Baymont by Wyndham Warrenton
2.5 star property
7.4 out of 10, Good, (1007)
"Very friendly staff. Nice place to stay"
United States
Bobby
The price is AU$151
includes taxes & fees
2 Nov - 3 Nov
Baymont by Wyndham Warrenton
Best Western Plus St. Louis West-Westport
2.5 star property
8.0 out of 10, Very good, (1014)
"It was a very nice place"
United States
Jill
The price is AU$154
includes taxes & fees
17 Nov - 18 Nov
Best Western Plus St. Louis West-Westport
Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
9.4 out of 10, Exceptional, (810)
"Room and bathroom were very clean. Plenty of parking. And the breakfast was wonderful, plenty of options to choose from."
United States
Bryce
The price is AU$248
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Days Inn by Wyndham St Peters/St Charles
2.0 star property
6.4 out of 10, (997)
"The carpet felt a little damp but aside from that the room was clean and comfortable. "
United States
Nikki
The price is AU$114
includes taxes & fees
21 Oct - 22 Oct
Days Inn by Wyndham St Peters/St Charles
Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
8.8 out of 10, Excellent, (1014)
"Great hotel! "
United States
Jeffrey Frank
The price is AU$158
includes taxes & fees
27 Oct - 28 Oct
Sleep Inn & Suites O'Fallon MO - Technology Drive
Hollywood Casino & Hotel St. Louis
3.5 star property
8.4 out of 10, Very good, (2174)
"Always our favorite place to stay!"
United States
Julie
The price is AU$190
includes taxes & fees
26 Oct - 27 Oct
Hollywood Casino & Hotel St. Louis
Best Western Plus Washington Hotel
2.5 star property
9.0 out of 10, Wonderful, (612)
"Would stay again. "
United States
Alisa
The price is AU$226
includes taxes & fees
20 Oct - 21 Oct
Best Western Plus Washington Hotel
AC Hotel by Marriott St. Louis Chesterfield
3.5 star property
9.2 out of 10, Wonderful, (210)
"Loved my stay here "
United States
nakia
The price is AU$271
includes taxes & fees
30 Oct - 31 Oct
AC Hotel by Marriott St. Louis Chesterfield
Hampton Inn St. Charles St. Peters
2.5 star property
8.0 out of 10, Very good, (1017)
"Excellent hotel. Excellent location, friendly staff, and delicious breakfast."
United States
Jean ss
The price is AU$160
includes taxes & fees
18 Nov - 19 Nov
Hampton Inn St. Charles St. Peters
Elimwood Hotel, a Ramada by Wyndham
3.0 star property
7.4 out of 10, Good, (1013)
"Clean nice room, staff was all very friendly & helpful, exceptionally so. "
United States
Jeanne
The price is AU$156
includes taxes & fees
26 Oct - 27 Oct
Elimwood Hotel, a Ramada by Wyndham
Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
8.6 out of 10, Excellent, (803)
"Clean, well maintained hotel. Friendly staff, great breakfast. Close to shopping and restaurants."
United States
Theresa
The price is AU$172
includes taxes & fees
29 Oct - 30 Oct
Holiday Inn Express St. Louis West - O'Fallon by IHG
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
9.6 out of 10, Exceptional, (1014)
"Great staff and great amenities!"
United States
Alicia
The price is AU$196
includes taxes & fees
26 Oct - 27 Oct
Drury Plaza Hotel St. Louis St. Charles
Super 8 by Wyndham St Charles
2.0 star property
8.0 out of 10, Very good, (1014)
"Clean room and comfortable bed I would stay again. "
United States
janeice
The price is AU$134
includes taxes & fees
26 Oct - 27 Oct
Super 8 by Wyndham St Charles
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
3.0 star property
8.8 out of 10, Excellent, (1004)
"Clean room great staff"
United States
Jayson
The price is AU$195
includes taxes & fees
22 Oct - 23 Oct
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Super 8 by Wyndham Union
2.0 star property
8.2 out of 10, Very good, (621)
"Clean room great staff"
United States
Jayson
The price is AU$132
includes taxes & fees
12 Nov - 13 Nov
Super 8 by Wyndham Union
Super 8 by Wyndham Warrenton
2.0 star property
7.4 out of 10, Good, (603)
"I have stayed several times at this hotel, it is always very clean, the staff are super nice and very convenient to I-70; would recommend this hotel and I will definitely stay there again."
United States
Kimberly
The price is AU$116
includes taxes & fees
2 Nov - 3 Nov
Super 8 by Wyndham Warrenton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

More cheap accommodation in Defiance

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and Courtyard by Marriott St Louis Creve Coeur. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
Madison House 1 -Walk to Main St: This holiday home rental outside of Defiance is equipped with a pool table, air conditioning and WiFi to help you feel comfortable during your stay. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. Drury Plaza Hotel St. Louis Creve Coeur and Hampton Inn St. Charles St. Peters are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 20 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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