
Defiance Holidays
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Your Defiance Holiday
The lively atmosphere, progressive thinking and friendly locals are just some of the reasons why people love this rural city. Discover this exciting destination in whatever way you choose with a Defiance holiday package. You'll want to take in some sights during your trip to Defiance. Swing by leading attractions such as August A. Busch Memorial Conservation Area, Chandler Hill Vineyards and Montelle Winery. A few quick clicks is all it takes to put together your ideal Defiance holiday on Expedia.
Defiance Holiday
Defiance Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
Population | 160 |
Max Temp Winter | 4ºC |
Max Temp Summer | 32ºC |
Top Sights | Augusta Winery, Chandler Hill Vineyards and Montelle Winery |
Our pick of the best Defiance Hotel Deals

The Wildwood Hotel
Breakfast great! Pool: hot tub being renovated.
Reviewed on 12 Jan 2026

Ameristar Casino Resort and Spa
Everything was beautiful from the hotel staff to the room. It was great.
Reviewed on 10 Jan 2026

La Quinta Inn & Suites by Wyndham St. Louis Westport
Clean and comfortable room
Reviewed on 2 Jan 2026
Discover the most popular places to visit in Defiance

Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.

Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
What to do in Defiance

St. Louis Ghost Tour: Sinister Sins & Shadows

Best of St. Louis Small Group Tour w/ Arch & River Cruise












