Find LGBTQ welcoming hotels in Cape Girardeau, MO

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Top Cape Girardeau LGBT Welcoming Hotels

Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$156 per night from 26 Oct to 27 Oct
AU$156
26 Oct - 27 Oct
includes taxes & fees
9.4/10 Exceptional! (1,017 reviews)
Excellent service and clean hotel !
"Stayed at the same Drury we’ve been staying at for several years when traveling fro lower Alabama to Kansas City. We always plan our travel times to stay here. Clean, friendly people working and nice rooms."

Reviewed on 15 Oct 2025

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$121 per night from 23 Oct to 24 Oct
AU$121
23 Oct - 24 Oct
includes taxes & fees
9/10 Wonderful! (1,009 reviews)
"The hotel was nice, clean, and had a comfortable mattress."

Reviewed on 11 Oct 2025

Opens in a new windowPear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$121 per night from 23 Oct to 24 Oct
AU$121
23 Oct - 24 Oct
includes taxes & fees
8.8/10 Excellent! (1,009 reviews)
"Room was a bit on the small side, but comfortable."

Reviewed on 13 Oct 2025

Opens in a new windowPear Tree Inn Cape Girardeau Near the Medical Center
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Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$217 per night from 9 Nov to 10 Nov
AU$217
9 Nov - 10 Nov
includes taxes & fees
9.4/10 Exceptional! (455 reviews)
"Clean room."

Reviewed on 9 Oct 2025

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$156 per night from 26 Oct to 27 Oct
AU$156
26 Oct - 27 Oct
includes taxes & fees
9.4/10 Exceptional! (1,005 reviews)
"Very tasty buffet-style food every morning and evening, the suites were large & clean. All of the staff members were friendly & helpful: From the people at the front desk, to the folks preparing the food, to the housekeeping staff keeping the rooms and public areas all nice & tidy. 5 Stars!"

Reviewed on 9 Oct 2025

Opens in a new windowDrury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street, Cape Girardeau, MO
Fully refundable
The price is AU$164 per night from 2 Nov to 3 Nov
AU$164
2 Nov - 3 Nov
includes taxes & fees
9.4/10 Exceptional! (1,004 reviews)
"One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe"

Reviewed on 8 Oct 2025

Opens in a new windowHoliday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5
207 S Mt Auburn Rd, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is AU$183 per night from 30 Oct to 31 Oct
AU$183
30 Oct - 31 Oct
includes taxes & fees
9.6/10 Exceptional! (760 reviews)
"Seemed newly updated, very friendly staff"

Reviewed on 20 Oct 2025

Opens in a new windowHampton Inn Cape Girardeau I 55 East
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd, Cape Girardeau, MO
Fully refundable
The price is AU$142 per night from 16 Nov to 17 Nov
AU$142
16 Nov - 17 Nov
includes taxes & fees
8/10 Very Good! (856 reviews)
"Clean room and bathroom, the beds and pillows were comfortable, the bathroom and the room were both really spacious which my toddler loved after being in her car seat she had plenty of room to run freely. The location was safe as well and convenient having a Rhodes close by open late to get snacks ..."

Reviewed on 15 Oct 2025

Opens in a new windowCandlewood Suites Cape Girardeau by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Enjoy gay-friendly hotels in Cape Girardeau


What kinds of gay-friendly hotels are there in Cape Girardeau?


When you're looking for gay-friendly hotels in Cape Girardeau, you'll find a wide variety of options to choose from. These welcoming hotels come in all shapes and sizes and offer a diverse array of amenities and special features you can enjoy. Whether you're looking for something romantic, like hotels with spa facilities, or are more interested in rooms better fit for a solo traveller or a group of friends, you'll find it here. What these hotels all have in common, though, is strict anti-discrimination policies and insight into some of the most popular LGBTQ-friendly activities available in town.


What are the best gay-friendly hotels in Cape Girardeau like?


The best gay-friendly hotel in Cape Girardeau depends on what you're looking for in accommodation. Fortunately, you can easily find what you need, thanks to the multitude of available search filters. You can filter based on amenities you may be interested in, like hot tubs or pet-friendly policies, or you can sort by star rating. You can even filter by guest reviews to show only hotels that have received predominantly high marks from previous guests. Don't forget to mark the filter for LGBTQ-friendly hotels to only show anti-discriminatory hotels in your results.


How can I find deals on Cape Girardeau gay-friendly hotels?


You'll find plenty of deals on gay-friendly hotels in Cape Girardeau. If you want to increase your chances of finding a deal, try booking your stay in the off-season when prices are usually cheaper. Additionally, think about what amenities you may be willing to go without to drive the price down even further. Of course, booking a short distance away from prominent attractions can be an easy way to save while still being close to public transport routes that can get you to the action easily. Just keep in mind that these are general trends rather than solid rules, as prices fluctuate all the time and can be difficult to predict.


Why should I book a gay-friendly hotel in Cape Girardeau with Expedia?


Booking with Expedia makes your holiday planning easier than ever before. Not only will you be able to enjoy a massive selection of gay-friendly hotels in Cape Girardeau, but you can also book a flight as well. In fact, booking both through Expedia may even unlock some additional savings. Plus, you can take advantage of the Expedia Rewards program. Joining is completely free, and every booking earns you points that you can redeem later for additional discounts. Plus, you'll enjoy deep discounts on certain hotels simply by being a member.


Are gay-friendly hotels in Cape Girardeau fully refundable?


A fully refundable cancelation is a handy feature to have, and numerous gay-friendly hotels in Cape Girardeau offer it. Expedia is proud to host a wide variety of hotels that offer full refund – there's even a search-filter option for it. You'll be able to see all qualifying hotels clearly marked on your search results page without even having to click the hotels individually.

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