Find LGBTQ welcoming hotels in Cape Girardeau, MO

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Top Cape Girardeau LGBT Welcoming Hotels

Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is AU$161 per night from 23 Feb to 24 Feb
AU$161
23 Feb - 24 Feb
includes taxes & fees
9.4/10 Exceptional! (1,009 reviews)
This place feels like customer service from 1950. The service was outstanding

Reviewed on 23 Jan 2026

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is AU$113 per night from 23 Feb to 24 Feb
AU$113
23 Feb - 24 Feb
includes taxes & fees
9/10 Wonderful! (1,001 reviews)
Hotel and room very clean and comfortable. Staff were excellent. Friendly, courteous and helpful. 24/7 Coffee available. Don’t get that at high end hotels anymore. They did have issues with the TV’s. Sounded like. Spectrum issue. Breakfast was good and clean area. Looking for a night to stay when ...

Reviewed on 22 Jan 2026

Opens in a new windowPear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St Cape Girardeau MO
8.8/10 Excellent! (1,000 reviews)
Clean, comfortable room with nice shower

Reviewed on 9 Jan 2026

Opens in a new windowPear Tree Inn Cape Girardeau Near the Medical Center
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Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St. Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is AU$205 per night from 22 Feb to 23 Feb
AU$205
22 Feb - 23 Feb
includes taxes & fees
9.4/10 Exceptional! (484 reviews)
Room was spotless, comfy bed, friendly staff

Reviewed on 20 Jan 2026

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is AU$145 per night from 23 Feb to 24 Feb
AU$145
23 Feb - 24 Feb
includes taxes & fees
9.4/10 Exceptional! (1,005 reviews)
Very nice staff. Welcomed my dog.

Reviewed on 22 Jan 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 out of 5
3253 William Street Cape Girardeau MO
Fully refundable
The price is AU$155 per night from 8 Feb to 9 Feb
AU$155
8 Feb - 9 Feb
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
Room was spacious and clean. Staff was nice and helpful. Good breakfast.

Reviewed on 19 Jan 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5
207 S Mt Auburn Rd Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is AU$173 per night from 5 Feb to 6 Feb
AU$173
5 Feb - 6 Feb
includes taxes & fees
9.6/10 Exceptional! (788 reviews)
Tonja at the front desk was wonderful! Please compliment her. We decided to leave at 5 am and she had coffee and fruit for us. Most importantly- she was so pleasant and handled her work so professionally.

Reviewed on 11 Jan 2026

Opens in a new windowHampton Inn Cape Girardeau I 55 East
Candlewood Suites Cape Girardeau by IHG
2.5 out of 5
485 S Mount Auburn Rd Cape Girardeau MO
Fully refundable
The price is AU$135 per night from 1 Feb to 2 Feb
AU$135
1 Feb - 2 Feb
includes taxes & fees
8/10 Very Good! (893 reviews)
The room itsself was exceptional. Everything was spotless and the beds are very comfortable. However, it was extremely noisy!! The arcade on the 4th floor kept kids running up and down the halls. I thought it strange that housekeeping will not bring towels to your room when requested, instead you ...

Reviewed on 24 Jan 2026

Opens in a new windowCandlewood Suites Cape Girardeau by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Enjoy gay-friendly hotels in Cape Girardeau


What kinds of gay-friendly hotels are there in Cape Girardeau?


When you're looking for gay-friendly hotels in Cape Girardeau, you'll find a wide variety of options to choose from. These welcoming hotels come in all shapes and sizes and offer a diverse array of amenities and special features you can enjoy. Whether you're looking for something romantic, like hotels with spa facilities, or are more interested in rooms better fit for a solo traveller or a group of friends, you'll find it here. What these hotels all have in common, though, is strict anti-discrimination policies and insight into some of the most popular LGBTQ-friendly activities available in town.


What are the best gay-friendly hotels in Cape Girardeau like?


The best gay-friendly hotel in Cape Girardeau depends on what you're looking for in accommodation. Fortunately, you can easily find what you need, thanks to the multitude of available search filters. You can filter based on amenities you may be interested in, like hot tubs or pet-friendly policies, or you can sort by star rating. You can even filter by guest reviews to show only hotels that have received predominantly high marks from previous guests. Don't forget to mark the filter for LGBTQ-friendly hotels to only show anti-discriminatory hotels in your results.


How can I find deals on Cape Girardeau gay-friendly hotels?


You'll find plenty of deals on gay-friendly hotels in Cape Girardeau. If you want to increase your chances of finding a deal, try booking your stay in the off-season when prices are usually cheaper. Additionally, think about what amenities you may be willing to go without to drive the price down even further. Of course, booking a short distance away from prominent attractions can be an easy way to save while still being close to public transport routes that can get you to the action easily. Just keep in mind that these are general trends rather than solid rules, as prices fluctuate all the time and can be difficult to predict.


Why should I book a gay-friendly hotel in Cape Girardeau with Expedia?


Booking with Expedia makes your holiday planning easier than ever before. Not only will you be able to enjoy a massive selection of gay-friendly hotels in Cape Girardeau, but you can also book a flight as well. In fact, booking both through Expedia may even unlock some additional savings. Plus, you can take advantage of the Expedia Rewards program. Joining is completely free, and every booking earns you points that you can redeem later for additional discounts. Plus, you'll enjoy deep discounts on certain hotels simply by being a member.


Are gay-friendly hotels in Cape Girardeau fully refundable?


A fully refundable cancelation is a handy feature to have, and numerous gay-friendly hotels in Cape Girardeau offer it. Expedia is proud to host a wide variety of hotels that offer full refund – there's even a search-filter option for it. You'll be able to see all qualifying hotels clearly marked on your search results page without even having to click the hotels individually.

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