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Our top choices for Byron hotels

Terrace/patio
Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester
8.4 out of 10, Very good, (200)
"Breakfast great and staff very helpful. "
Canada
John
The price is AU$239
includes taxes & fees
30 Jan - 31 Jan 2026
Residence Inn by Marriott Rochester Mayo Clinic Area
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (773)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is AU$153
includes taxes & fees
2 Jan - 3 Jan 2026
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Front of property
The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel
4.0 star property
Downtown Rochester
9.4 out of 10, Exceptional, (96)
"Excellent accommodations, amazing staff"
United States
Shannon
The price is AU$866
includes taxes & fees
1 Jan - 2 Jan 2026
The Towers At Kahler Grand Hotel
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (168)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is AU$271
includes taxes & fees
9 Jan - 10 Jan 2026
Broadway Plaza, Trademark Collection by Wyndham
2 indoor pools
TownePlace Suites by Marriott Rochester

TownePlace Suites by Marriott Rochester

TownePlace Suites by Marriott Rochester
3.0 star property
Rochester
8.8 out of 10, Excellent, (539)
"Hotel showed a lot of wear and tear. Front staff was helpful. "
United States
Heather
The price is AU$145
includes taxes & fees
5 Jan - 6 Jan 2026
TownePlace Suites by Marriott Rochester
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park
9.6 out of 10, Exceptional, (680)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is AU$159
includes taxes & fees
18 Jan - 19 Jan 2026
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.8 out of 10, Excellent, (766)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is AU$187
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Exterior
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3.0 star property
Kutzky Park
8.6 out of 10, Excellent, (947)
"It was great location- clean friendly convenience, good breakfast "
United States
ROCIO
The price is AU$148
includes taxes & fees
2 Jan - 3 Jan 2026
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.6 out of 10, Exceptional, (888)
"Great stay,clean and friendly"
United States
Janet
The price is AU$204
includes taxes & fees
2 Jan - 3 Jan 2026
Home2 Suites by Hilton Rochester Mayo Clinic Area
Double Room, 2 Queen Beds
Red Carpet Inn Rochester

Red Carpet Inn Rochester

Red Carpet Inn Rochester
2.0 star property
Rochester
7.6 out of 10, Good, (534)
"Quite and comfort"
United States
Shamso
Red Carpet Inn Rochester
Free daily full breakfast
Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.5 star property
Rochester
8.8 out of 10, Excellent, (835)
"Great stay!"
United States
William
The price is AU$118
includes taxes & fees
24 Jan - 25 Jan 2026
Quality Inn & Suites Mayo Clinic Area
View from property
Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic
3.5 star property
Downtown Rochester
8.4 out of 10, Very good, (527)
"it was a fantastic "
United States
Paul
The price is AU$291
includes taxes & fees
2 Jan - 3 Jan 2026
Marriott Rochester Mayo Clinic
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (856)
"Yes the workers are amazing "
United States
Luciana
The price is AU$184
includes taxes & fees
8 Jan - 9 Jan 2026
Hilton Garden Inn Rochester Downtown, MN
Terrace/patio
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (479)
"Everything was exceptional as usual!"
United States
Colin
The price is AU$196
includes taxes & fees
18 Jan - 19 Jan 2026
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester
9.6 out of 10, Exceptional, (483)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is AU$218
includes taxes & fees
17 Jan - 18 Jan 2026
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Exterior
Staybridge Suites Rochester - Commerce Dr NW by IHG

Staybridge Suites Rochester - Commerce Dr NW by IHG

Staybridge Suites Rochester - Commerce Dr NW by IHG
3.0 star property
Rochester
8.8 out of 10, Excellent, (511)
"Staff very helpful and friendly. Room clean and spacious for our four adults and a baby."
United States
Amanda
The price is AU$193
includes taxes & fees
23 Jan - 24 Jan 2026
Staybridge Suites Rochester - Commerce Dr NW by IHG
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (894)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is AU$138
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Exterior
Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1000)
"Love room, breakfast, and shuttle to Mayo. We always stay there"
United States
Laureen
The price is AU$154
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Rochester-North
Lobby
Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very good, (435)
"The place was very clean, very quiet and the staff was extremely helpful. We will be back"
United States
Melissa
The price is AU$147
includes taxes & fees
1 Jan - 2 Jan 2026
Americas Best Value Inn & Suites Spring Valley
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency, Upgrade)
Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
2.5 star property
Rochester
9.0 out of 10, Wonderful, (586)
"Nice place to stay "
United States
Melissa
The price is AU$139
includes taxes & fees
9 Jan - 10 Jan 2026
Sleep Inn & Suites West-Near Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Byron attractions

Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.
See properties

East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.
See properties

Top Byron Hotel Reviews

Recent Reviews in Byron

Aspen Suites

Aspen Suites

10/10 Excellent
"Clean room"
doris 1-night trip
Posted 1 day ago
Aspen Suites

More cheap accommodation in Byron

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

4210 Highway 52 North Rochester MN
The price is AU$113 per night from 5 Jan to 6 Jan
AU$113
5 Jan - 6 Jan 2026
includes taxes & fees
7.8/10 Good! (1,000 reviews)

Frequently asked questions

Where is the best place to stay in Byron?
Located 9 mi (14.4 km) from the heart of Byron, Kahler Grand Hotel is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Kahler Inn and Suites - Mayo Clinic Area and Hampton Inn Rochester-South. See all available top hotels, or vacation rentals in Byron.
What are some of the best holiday rentals that Byron has to offer?
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: This holiday home rental outside of Byron offers a patio, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind. See all vacation rentals in Byron.
If I need to cancel my hotel reservation in Byron, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Byron.
How is it to stay in Byron?
Visitors can enjoy all that Byron has to offer, including the zoo, golf courses and bars. Tourists can also enjoy the city's parks and art. In Byron, there are 2 hotels and other accommodation options to choose from. Find out more about Byron.
What should I see while I'm in Byron?
Favourite places to visit include Putting Green, Links of Byron Mini Golf and Cheery Meadows Center. A couple of additional sights to add to your itinerary are High Point Shopping Center and Byron Town Square. Take a look at what more there is to see and do in Expedia's Byron guide.
What's the seasonal weather in Byron?
The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -6°C. The snowiest months in Byron are January, March, April and February, with each month seeing an average of 19 cm of snowfall.

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