All hotels in Upstate South Carolina, South Carolina
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
All hotels in Upstate South Carolina, South Carolina
We have found 2952 Upstate South Carolina Hotels
- Candlewood Suites Greenville by IHG
- Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
- Home2 Suites by Hilton Anderson Downtown
- Comfort Inn & Suites Spartanburg North
- Comfort Suites Anderson-Clemson
- Comfort Suites Piedmont - Greenville South
- Days Inn by Wyndham Clemson
- Home2 Suites by Hilton Greenville Airport
- Fairfield Inn & Suites Seneca Clemson Univ Area
- Quality Inn Seneca Clemson Area US-123
- Hilton Garden Inn Spartanburg
- Days Inn by Wyndham Greenville South/Mauldin
- Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
- Holiday Inn Express & Suites Clemson by IHG
- Budget Inn Greenville By Hotel O I-85
- Days Inn by Wyndham Greenville
- Greenville Pelham Inn by IHG
- Hampton Inn Gaffney
- Days Inn by Wyndham Spartanburg
- Hampton Inn Anderson/ Alliance Business Park
- Hampton Inn Greenville/I-385 Haywood Mall
- Baymont by Wyndham Anderson Clemson
- Hampton Inn Greenville/Travelers Rest
- Hampton Inn Easley
- Swamp Rabbit Inn
- Quality Inn Simpsonville - Greenville
- Rodeway Inn Expo Center
- Home2 Suites by Hilton Duncan
- Courtyard Marriott Clemson
- Microtel Inn by Wyndham Duncan/Spartanburg
- Days Inn by Wyndham Clinton / Laurens I-26
- WoodSpring Suites Greenville Simpsonville
- Hampton Inn & Suites Clinton - I-26
- Super 8 by Wyndham Greer/Spartanburg Area
- Rodeway Inn Anderson North - Clemson
- Hampton Inn & Suites Greenville/Spartanburg I-85, SC
- Best Western Seneca-Clemson
- WoodSpring Suites Greenville Central I-85
- Extended Stay America Premier Suites Greenville Woodruff Rd
- Country Inn & Suites by Radisson, Anderson, SC
- stayAPT Suites Greenville Greer BMW
- Residence Inn by Marriott Anderson Clemson
- Holiday Inn Spartanburg Northwest by IHG
- Staybridge Suites Greenville I-85 Woodruff Road by IHG
- Swamp Rabbit Inn Travelers Rest
- Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
- Holiday Inn Express & Suites Greenville-I-85 & Woodruff Rd by IHG
- Comfort Suites Clinton near Presbyterian College
- Red Roof Inn Greenville
- Holiday Inn Express & Suites Greenville S- Piedmont by IHG
- Holiday Inn Express Anderson by IHG
- Hampton Inn Clemson-University Area
- Quality Inn Duncan - Spartanburg West
- USA Economy Lodge
- Homewood Suites by Hilton Greenville
- Super 8 by Wyndham Piedmont Greenville Area
- Red Roof Inn Spartanburg – I-26
- Fairfield By Marriott Inn & Suites Piedmont Greenville
- Hampton Inn Anderson
- Hometowne Studios Greenville
- Baymont by Wyndham Gaffney
- Hotel Domestique
- Fairfield Inn & Suites by Marriott Anderson Clemson
- Motel 6 Spartanburg, Sc – Northwest / Business 85
- Quality Inn Spartanburg Northwest
- Rodeway Inn Union
- Days Inn by Wyndham Simpsonville
- WoodSpring Suites Spartanburg - Duncan
- Quality Inn Greer - Greenville
- Quality Inn Union US Hwy 176
- Residence Inn by Marriott Spartanburg
- Residence Inn by Marriott Spartanburg Westgate
- Super 8 by Wyndham Anderson/Clemson Area
- Red Roof Inn Spartanburg - I-85
- Quality Inn Gaffney I-85
- Residence Inn by Marriott Greenville-Spartanburg Airport
- Pettigru Place Bed & Breakfast
- BEAUTIFUL Newly Built Retreat w/Private Marina Boat Slip at Upper Lake Keowee!!!
- Americas Best Value Inn Anderson, SC
- SUN AND SAND MOTEL
- Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan
- Studio Near Falls Park on Reedy – Functional Space for Long Stays - 2 Units
- Motel 6 Simpsonville, SC - Greenville
- Liberty Hall Bed and Breakfast
- Econo Lodge Clemson - University Area
- The Bleckley Inn
- Charming 4-bedroom farmhouse w/ WiFi, AC in lovely Eastatoee Valley, Sunset, SC.
- Countryside Haven
- Red Roof Inn & Suites Duncan
- Whole Hearts Bed and Breakfast
- Red Roof Inn Gaffney
- AUG/SEPT SALE FIREPIT TREE-FORT RETREAT 6 miles to Reedy Falls, 1.5 to Conastee
- MULTIPLE Cottage stay on Saluda River Farms for up to 20+
- Budget Inn Express
- Sleep Inn Gaffney at I-85
- Baymont by Wyndham Duncan/Spartanburg
- Econo Lodge Gaffney
Let Expedia take you to the best Hotels in Upstate South Carolina. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.