All hotels in Southwest Illinois, Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
All hotels in Southwest Illinois, Illinois
We have found 766 Southwest Illinois Hotels
- Hilton St. Louis Airport
- Homewood Suites by Hilton St Louis - Galleria
- Holiday Inn Express & Suites St. Louis South - I-55 by IHG
- Pear Tree Inn Cape Girardeau West
- Baymont by Wyndham Litchfield
- The Great Rivers, an Ascend Collection Hotel
- Courtyard by Marriott St. Louis Brentwood
- HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh
- Drury Inn & Suites Cape Girardeau
- Super 8 by Wyndham St. Louis Airport
- Comfort Inn Alton near I-255
- Drury Inn & Suites Jackson MO
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Red Roof Inn St Louis - Westport/ Maryland Heights
- Home2 Suites by Hilton St. Louis/Forest Park
- Best Western Plus Sikeston I-55
- Fairfield Inn & Suites by Marriott St. Louis South
- Extended Stay America Suites St Louis Westport Central
- Courtyard St. Louis Airport/Earth City
- Residence Inn By Marriott St. Louis Clayton
- Comfort Inn St. Louis Airport
- Baymont by Wyndham Festus
- Holiday Inn Express & Suites St. Louis West - Fenton by IHG
- Candlewood Suites Cape Girardeau by IHG
- Comfort Inn Festus - St Louis South
- Cobblestone Inn & Suites - Altamont
- Best Western Plus Parkway Hotel
- Sheraton Westport Chalet Hotel St. Louis
- Holiday Inn St. Louis Arpt West-Earth City by IHG
- St. Louis Airport Hotel
- Fairfield Inn & Suites by Marriott Cape Girardeau
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Hampton Inn St. Louis/Westport
- Hotel Indigo St. Louis - Downtown by IHG
- Holiday Inn Express and Suites Alton St Louis Area by IHG
- Super 8 by Wyndham Metropolis
- Courtyard by Marriott St. Louis West County
- Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd
- Marriott St. Louis West
- Quality Inn Cape Girardeau North
- Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
- WoodSpring Suites St. Louis Arnold
- Courtyard by Marriott Cape Girardeau Downtown
- Holiday Inn Express & Suites St Louis Airport by IHG
- Economy Inn & Suites
- Extended Stay America Select Suites - St. Louis - Airport - Central
- Embassy Suites by Hilton St. Louis Airport
- The Lodge at Grant's Trail
- Quality Inn Florissant - St Louis
- Holiday Inn Express & Suites Perryville by IHG
- SpringHill Suites by Marriott St. Louis Airport/Earth City
- Microtel Inn & Suites by Wyndham Sainte Genevieve
- Tru By Hilton Cape Girardeau
- Baymont By Wyndham Bridgeton St Louis
- Holiday Inn Express & Suites Litchfield West by IHG
- Fairfield Inn & Suites St Louis Westport
- Silo Farm Haus- located in the heart of wine country!
- Super 8 by Wyndham Staunton
- MainStay Suites St Louis Airport
- Cozy, Fun, and One-Of-A-Kind!
- Hampton Inn & Suites St. Louis/Alton
- Hampton Inn Cape Girardeau I 55 East
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Super 8 by Wyndham Sikeston/Miner Area
- Homewood Suites by Hilton St. Louis Westport
- Super 8 by Wyndham Perryville
- Quality Inn Litchfield Route 66
- Extended Stay America Select Suites St Louis Earth City
- Staybridge Suites St Louis - Westport by IHG
- Motel 6 Metropolis, IL
- Spark by Hilton St. Louis Southwest
- Hampton Inn by Hilton Litchfield
- Seven Gables, St. Louis West, a Tribute Portfolio Hotel
- Sheraton Westport Plaza Hotel St. Louis
- Hampton Inn & Suites St. Louis/South I-55
- Super 8 by Wyndham Charleston/Sikeston East MO
- Super 8 by Wyndham Pevely
- Comfort Suites St. Louis - Sunset Hills
- Benton Park Inn
- Pear Tree Inn St. Louis Convention Center
- Motel 6 Litchfield, IL
- Residence Inn by Marriott St. Louis West County
- Intown Suites Extended Stay St. Louis Mo - Hazelwood
- Super 8 by Wyndham Harrisburg
- Days Inn & Suites By Wyndham Festus
- Town House Inn Cape Giradreau
- Gorgeous Ultramodern 2BR Loft + Patio
- Welcome Suites Hazelwood
- Grand Center Inn
- Americas Best Value Inn St. Louis Downtown
- Carlin Villa Motel
- Hotel 7 Vienna
- Beautiful, Rehabbed Unit in Shaw Community 4228a
- Comfort Suites Jackson-Cape Girardeau
Let Expedia take you to the best Hotels in Southwest Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.