Photo by Carl Anderson
Search Southwest Illinois hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southwest Illinois
Family friendly
Check prices for these dates
Top hotels and accommodation in Southwest Illinois
Comfort Suites Mount Vernon
Mount Vernon
9.0 out of 10, Wonderful, (1006)
"The room was nice, featuring a comfortable sitting area where I could relax and still watch TV."
Sharon
Travelling for leisure
The price is AU$186
includes taxes & fees
7 Dec - 8 Dec
Drury Plaza Hotel Mt. Vernon
Mount Vernon
9.6 out of 10, Exceptional, (1561)
"Room was very clean, fekt safe and liked the breakfast, dimnner and drinks."
Constance
Travelling with partner
The price is AU$161
includes taxes & fees
11 Dec - 12 Dec
Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
9.0 out of 10, Wonderful, (1003)
"Nice and clean room, will stay again."
Susan
Travelling with family
The price is AU$163
includes taxes & fees
21 Dec - 22 Dec
SureStay Hotel by Best Western Whittington Rend Lake
Whittington
8.8 out of 10, Excellent, (902)
"But the room was clean and nice."
Cynthia
Travelling for leisure
The price is AU$121
includes taxes & fees
31 Dec - 1 Jan 2026
Best Western Plus MidAmerica Hotel
Mascoutah
9.0 out of 10, Wonderful, (1002)
"Well mainained, clean, friendly staff, efficient check in check out"
Allen
Travelling with partner
The price is AU$189
includes taxes & fees
1 Jan - 2 Jan 2026
Comfort Inn & Suites Marion I-57
Marion
9.4 out of 10, Exceptional, (1000)
"Michell who runs the kitchen is awesome."
Nadine
Travelling for leisure
The price is AU$196
includes taxes & fees
5 Jan - 6 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southwest Illinois, IL
Showing deals for:12 Dec - 14 Dec
Image gallery for Red Bud Country Inn
Red Bud Country Inn
Red Bud
9.0/10Wonderful (50 reviews)
15% off
Price is AU$286
for 2 nights, 1 room
AU$143 per night
includes taxes & fees
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Central United States attractions
Learn more about Southwest Illinois
Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.
Photo by Carl Anderson
Open Photo by Carl Anderson
Top Southwest Illinois Hotel Reviews
Recent Reviews in Southwest Illinois
Comfort Suites Mount Vernon
10/10 Excellent
More cheap accommodation in Southwest Illinois
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is AU$74 per night from 14 Dec to 15 Dec
AU$74
14 Dec - 15 Dec
includes taxes & fees
7/10 Good! (1,002 reviews)
Explore a world of travel with Expedia
- Aviston Hotels
- Baldwin Hotels
- Boutique Hotels in Belleville
- Belleville Hotels
- Breese Hotels
- Carlyle Hotels
- Hotels near Carlyle Lake
- Cheap Hotels in Central City
- Motels in Central City
- Centralia Hotels
- Cheap Hotels in Collinsville
- Holiday Homes in Dix
- Cabin Rentals in Freeburg
- Freeburg Hotels
- Germantown Hotels
- B&B in Highland
- Highland Hotels
- Motels in Highland
- Hoyleton Hotels
- Holiday Homes in Lebanon
- Beach Hotels in Lebanon
- Cheap Hotels in Lebanon
- Hotels with Pool in Lebanon
- Luxury Hotels in Lebanon
- Romantic Hotels in Lebanon
- Lebanon Hotels
- Cheap Hotels in Marine
- Marissa Hotels
- B&B in Mascoutah
- Mascoutah Hotels
- Hotels near McKendree University
- Caravan Parks in Nashville
- Farmstay in Nashville
- Holiday Homes in Nashville
- Cheap Hotels in Nashville
- Family Hotels in Nashville
- Golf Hotels in Nashville
- Nashville Hotels
- Resort in Nashville
- Luxury Hotels in New Athens
- New Athens Hotels
- Romantic Hotels in O'Fallon
- O'fallon Hotels
- Odin Hotels
- Caravan Parks in Percy
- Percy Hotels
- Pinckneyville Hotels
- Luxury Hotels in Red Bud
- Richview Hotels
- Hotels near Scott Air Force Base
- Scott Air Force Base Hotels
- B&B in Sesser
- Farmstay in Sesser
- Resort in Sesser
- Condo Rentals in Shiloh
- Shiloh Hotels
- B&B in Smithton
- Cheap Hotels in Smithton
- Luxury Hotels in Smithton
- Smithton Hotels
- Motels in Smithton
- Family Hotels in Sparta
- Luxury Hotels in Sparta
- Sparta Hotels
- Motels in Sparta
- B&B in Swansea
- Caravan Parks in Swansea
- Chalets in Swansea
- Guest Houses in Swansea
- Holiday Homes in Swansea
- Boutique Hotels in Swansea
- Cheap Hotels in Swansea
- Family Hotels in Swansea
- Hotels with Pool in Swansea
- Luxury Hotels in Swansea
- Pet Friendly Hotels in Swansea
- Swansea Hotels
- Lodges in Swansea
- Motels in Swansea
- Villas in Swansea
- Tamaroa Hotels
- Lgbt Welcoming Hotels in Troy
- Waltonville Hotels
