All hotels in Southern Illinois, Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
All hotels in Southern Illinois, Illinois
We have found 1207 Southern Illinois Hotels
- Drury Inn & Suites St. Louis Fairview Heights
- Drury Inn & Suites Marion
- Drury Plaza Hotel Mt. Vernon
- Quality Inn O'Fallon - St. Louis - Shiloh
- Drury Inn & Suites St. Louis O'Fallon, IL
- Super 8 by Wyndham O'Fallon
- Drury Inn & Suites St. Louis Collinsville
- Ramada by Wyndham Effingham
- Comfort Inn Edwardsville - St. Louis
- Quality Inn & Suites near St. Louis and I-255
- Walker's Bluff Casino Resort
- Quality Inn & Suites Metropolis I-24
- Baymont by Wyndham Marion
- Baymont by Wyndham Effingham
- Americas Best Value Inn Collinsville St. Louis
- Comfort Suites Fairview Heights - St. Louis
- Country Inn & Suites by Radisson, Effingham, IL
- The Principal Hotel
- Radisson Hotel Fairview Heights - St. Louis
- Comfort Suites Mount Vernon
- Motel 6 Caseyville, IL - Caseyville Il
- Country Inn & Suites by Radisson, Fairview Heights, IL
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Best Western Marion Hotel
- Best Western St. Louis Fairview Heights
- Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
- Super 8 by Wyndham Collinsville St. Louis
- Comfort Inn Collinsville near St. Louis
- Holiday Inn Express Metropolis by IHG
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Holiday Inn Express & Suites Edwardsville by IHG
- Super 8 by Wyndham Fairview Heights-St. Louis
- Super 8 by Wyndham Mt. Vernon IL
- Best Western Plus MidAmerica Hotel
- Country Inn & Suites by Radisson, Marion, IL
- Motel 6 Marion, IL
- Holiday Inn Express Troy by IHG
- Quality Inn Effingham North
- Quality Inn Carbondale University area
- Holiday Inn Express & Suites Effingham by IHG
- DoubleTree by Hilton Collinsville - St. Louis
- Red Lion Inn & Suites Caseyville
- Super 8 by Wyndham Carbondale
- Quality Inn & Suites Marion
- Hampton Inn Carbondale
- Comfort Inn & Suites Marion I-57
- Days Inn by Wyndham Mount Vernon
- Holiday Inn Express & Suites Carbondale - University Area by IHG
- Quality Inn Mount Vernon, IL
- Best Western Delta Inn
- Holiday Inn Express & Suites O'Fallon/Shiloh by IHG
- Country Hearth Inn & Suites Edwardsville St. Louis
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- La Quinta Inn & Suites by Wyndham Effingham
- Country View Inn & Suites
- Super 8 by Wyndham Metropolis
- SureStay Hotel by Best Western Whittington Rend Lake
- Comfort Suites Mattoon East
- Economy Inn & Suites
- Red Roof Inn St Louis - Troy, IL
- Days Inn by Wyndham Collinsville/St. Louis
- Red Lion Inn & Suites Pontoon Beach
- Days Inn & Suites by Wyndham Casey
- Home2 Suites by Hilton Carbondale
- Comfort Inn & Suites O'Fallon - St. Louis Area
- Extended Stay America Select Suites - St. Louis - O' Fallon, IL
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Comfort Suites Effingham Central
- Cobblestone Inn & Suites - Altamont
- Baymont by Wyndham O'Fallon St. Louis Area
- Best Western Heartland Inn
- Super 8 by Wyndham Marion
- Super 8 by Wyndham Troy IL/St. Louis Area
- Best Western Plus Pontoon Beach
- Seasons Inn & Suites Highland
- Sleep Inn O'Fallon near I-64
- Comfort Inn & Suites Carbondale University Area
- Hampton Inn & Suites Effingham
- Hampton Inn Collinsville
- Hampton Inn O'Fallon
- Holiday Inn Effingham by IHG
- Comfort Inn & Suites Greenville I-70
- Super 8 by Wyndham Belleville St. Louis Area
- Fairgrounds Inn
- Best Western Saluki Inn
- Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
- Super 8 by Wyndham Grayville
- Best Western U. S. Inn
- Best Western Troy Hotel
- Welcome Suites
- Holiday Inn Express & Suites Vandalia by IHG
- Holiday Inn Express Hotel & Suites Sparta by IHG
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Indian Mound Motel
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.