All hotels in Southern Illinois, Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
All hotels in Southern Illinois, Illinois
We have found 1160 Southern Illinois Hotels
- Drury Inn & Suites St. Louis Fairview Heights
- Best Western Delta Inn
- Drury Inn & Suites St. Louis O'Fallon, IL
- Drury Plaza Hotel Mt. Vernon
- Comfort Suites Mount Vernon
- Super 8 by Wyndham O'Fallon
- Comfort Suites Fairview Heights - St. Louis
- Baymont by Wyndham Effingham
- Quality Inn O'Fallon IL - St. Louis
- Drury Inn & Suites Marion
- Best Western Marion Hotel
- Quality Inn & Suites near St. Louis and I-255
- Red Lion Inn & Suites Pontoon Beach
- Holiday Inn Express Metropolis by IHG
- Drury Inn & Suites St. Louis Collinsville
- Country Inn & Suites by Radisson, Fairview Heights, IL
- Quality Inn & Suites Metropolis I-24
- Super 8 by Wyndham Troy IL/St. Louis Area
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Sleep Inn O'Fallon near I-64
- Country Hearth Inn & Suites Edwardsville St. Louis
- Best Western Plus MidAmerica Hotel
- Country Inn & Suites by Radisson, Effingham, IL
- DoubleTree by Hilton Collinsville - St. Louis
- Best Western Plus Pontoon Beach
- Red Roof Inn St Louis - Troy, IL
- Holiday Inn Express & Suites Effingham by IHG
- Holiday Inn Carbondale-Conference Center by IHG
- Comfort Inn & Suites O'Fallon - St. Louis Area
- Days Inn by Wyndham Collinsville/St. Louis
- Candlewood Suites O Fallon by IHG
- Welcome Suites
- Best Western Saluki Inn
- Quality Inn & Suites Marion
- Radisson Hotel Fairview Heights - St. Louis
- Holiday Inn Express Troy by IHG
- Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
- Comfort Suites Mattoon East
- Walker's Bluff Casino Resort
- Holiday Inn Express & Suites O'Fallon/Shiloh by IHG
- Days Inn by Wyndham Salem, Illinois
- Best Western St. Louis Fairview Heights
- Super 8 by Wyndham Carbondale
- Super 8 by Wyndham Fairview Heights-St. Louis
- Red Lion Inn & Suites Caseyville
- Country Inn & Suites by Radisson, Marion, IL
- The Principal Hotel
- Fairfield Inn & Suites by Marriott O'Fallon, IL
- Unique Suites Hotel
- Holiday Inn Express & Suites Edwardsville by IHG
- Baymont by Wyndham O'Fallon St. Louis Area
- Comfort Inn Collinsville near St. Louis
- Seasons Inn & Suites Highland
- La Quinta Inn & Suites by Wyndham Effingham
- Econo Lodge Inn & Suites Fairview Heights - St. Louis
- Fairgrounds Inn
- Baymont by Wyndham Marion
- Holiday Inn Express & Suites Mattoon by IHG
- Home2 Suites by Hilton Carbondale
- Comfort Inn & Suites Marion I-57
- Hampton Inn St. Louis - Columbia
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
- Days Inn by Wyndham Mount Vernon
- La Quinta Inn & Suites by Wyndham Pontoon Beach
- Hampton Inn O'Fallon
- Comfort Inn Edwardsville - St. Louis
- Hampton Inn Carbondale
- Royal Relax Inn
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Best Western Troy Hotel
- La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
- Motel 6 Marion, IL
- Super 8 by Wyndham Metropolis
- Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
- University Inn of Carbondale
- Economy Inn & Suites
- Super 8 by Wyndham Grayville
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- SureStay Hotel by Best Western Whittington Rend Lake
- Econo Lodge Inn & Suites Granite City - St. Louis
- Quality Inn Mount Vernon, IL
- Indian Mound Motel
- Hilton Garden Inn Mattoon, Il
- Ramada by Wyndham Effingham
- Hampton Inn & Suites St. Louis-Edwardsville
- Motel 6 Effingham, IL
- Holiday Inn Express Hotel & Suites Sparta by IHG
- Quality Inn Effingham North
- Americas Best Value Inn Collinsville St. Louis
- Baymont by Wyndham Chester IL
- Best Western Heartland Inn
- Holiday Inn Express & Suites Salem by IHG
- Best Western Plus Centralia Hotel & Suites
- Holiday Inn Express & Suites Vandalia by IHG
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.