All hotels in Southern Illinois, Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
All hotels in Southern Illinois, Illinois
We have found 1166 Southern Illinois Hotels
- Drury Inn & Suites St. Louis Fairview Heights
- Best Western St. Louis Fairview Heights
- Baymont by Wyndham Effingham
- Ramada by Wyndham Effingham
- Drury Plaza Hotel Mt. Vernon
- Country Inn & Suites by Radisson, Fairview Heights, IL
- Drury Inn & Suites St. Louis O'Fallon, IL
- Super 8 by Wyndham O'Fallon
- Holiday Inn Express Metropolis by IHG
- Comfort Suites Fairview Heights - St. Louis
- The Principal Hotel
- Quality Inn & Suites near St. Louis and I-255
- Comfort Suites Mount Vernon
- Baymont by Wyndham Marion
- Drury Inn & Suites St. Louis Collinsville
- Drury Inn & Suites Marion
- Super 8 by Wyndham Collinsville St. Louis
- Quality Inn O'Fallon - St. Louis - Shiloh
- Radisson Hotel Fairview Heights - St. Louis
- Country Inn & Suites by Radisson, Effingham, IL
- Motel 6 Caseyville, IL - Caseyville Il
- Comfort Inn Edwardsville - St. Louis
- Super 8 by Wyndham Mt. Vernon IL
- Best Western Marion Hotel
- Quality Inn & Suites Metropolis I-24
- Best Western Troy Hotel
- Best Western U. S. Inn
- Super 8 by Wyndham Troy IL/St. Louis Area
- Walker's Bluff Casino Resort
- Days Inn by Wyndham Collinsville/St. Louis
- Holiday Inn Express Troy by IHG
- La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
- Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
- Super 8 by Wyndham Mattoon
- La Quinta Inn & Suites by Wyndham Effingham
- DoubleTree by Hilton Collinsville - St. Louis
- Super 8 by Wyndham Fairview Heights-St. Louis
- Days Inn & Suites by Wyndham Caseyville
- Welcome Suites
- Comfort Inn & Suites O'Fallon - St. Louis Area
- Comfort Inn Collinsville near St. Louis
- Sleep Inn O'Fallon near I-64
- Holiday Inn Express & Suites Edwardsville by IHG
- Quality Inn Carbondale University area
- Holiday Inn Express & Suites Carbondale - University Area by IHG
- Quality Inn Effingham North
- Home2 Suites by Hilton Carbondale
- Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
- Comfort Inn & Suites Marion I-57
- Quality Inn Mount Vernon, IL
- Quality Inn & Suites Vandalia near I-70 and Hwy 51
- Best Western Plus MidAmerica Hotel
- Best Western Saluki Inn
- Red Lion Inn & Suites Caseyville
- Super 8 by Wyndham Carbondale
- Comfort Suites Mattoon East
- Best Western Heartland Inn
- SureStay Hotel by Best Western Whittington Rend Lake
- Red Lion Inn & Suites Pontoon Beach
- Cobblestone Inn & Suites - Altamont
- Holiday Inn Effingham by IHG
- Super 8 by Wyndham Belleville St. Louis Area
- Hampton Inn Carbondale
- Super 8 by Wyndham Metropolis
- Extended Stay America Select Suites - St. Louis - O' Fallon, IL
- Days Inn & Suites by Wyndham Casey
- Holiday Inn Express & Suites Effingham by IHG
- Best Western Delta Inn
- Quality Inn & Suites Marion
- Country Hearth Inn & Suites Edwardsville St. Louis
- Holiday Inn Express & Suites O'Fallon/Shiloh by IHG
- Country View Inn & Suites
- Super 8 by Wyndham Grayville
- Economy Inn & Suites
- Hampton Inn St. Louis - Columbia
- Country Inn & Suites by Radisson, Marion, IL
- Americas Best Value Inn Collinsville St. Louis
- Holiday Inn Express & Suites Mattoon by IHG
- Best Western Plus Pontoon Beach
- Days Inn by Wyndham Mount Vernon
- Seasons Inn & Suites Highland
- Super 8 by Wyndham Marion
- Baymont by Wyndham O'Fallon St. Louis Area
- Motel 6 Marion, IL
- Red Roof Inn St Louis - Troy, IL
- Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
- Hampton Inn Collinsville
- Best Western Flora Inn
- Hampton Inn & Suites Effingham
- Pinckeyville Inn and Suites
- Comfort Inn & Suites Greenville I-70
- Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
- Comfort Suites Effingham Central
- Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.