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Top Mountain Upstate South Carolina Hotels

Drury Inn & Suites Greenville

10 Carolina Point Pkwy Greenville SC

2 hours drive from Clemson University

Stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...

9.6/10 Exceptional! (1,022 reviews)

"Drury does a great job w/ amenities, staff and cleaning. Only minor issues nothing to report."

Reviewed on 26 June 2026

The Westin Poinsett Greenville

120 South Main St Greenville SC

1 hour drive from Clemson University

Stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle and 24-hour room service. Our guests praise the helpful ...

9.4/10 Exceptional! (1,000 reviews)

"Always our go to place to stay in Greenville,SC. Never disappointed"

Reviewed on 14 June 2026

Hampton Inn Gaffney

115 Nancy Creek Rd Gaffney SC

3 hours drive from Clemson University

Stay at this hotel in Gaffney. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions Gaffney ...

8.8/10 Excellent! (735 reviews)

"excellent breakfast friendly staff"

Reviewed on 27 June 2026

See all 3,017 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.