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Cheap Flights from St. Louis (STL) to San Francisco (SFO)

View AU$240 flight on Sat, 15 Aug 2026Opens in a new window

Popular airlines from Lambert-St. Louis International Airport (STL) to San Francisco International Airport (SFO)

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Cheap Flights from St. Louis (STL) to San Francisco (SFO)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sun, 16 Aug - Thu, 20 Aug
STL
St. Louis
SFO
San Francisco
AU$636 Return, found 11 hours ago
AU$636
Return
found 11 hours ago
Select American Airlines flight, departing Sun, 16 Aug from St. Louis to San Francisco, returning Thu, 20 Aug, priced at AU$636 found 11 hours ago
Delta
Sun, 16 Aug - Thu, 20 Aug
STL
St. Louis
SFO
San Francisco
AU$636 Return, found 11 hours ago
AU$636
Return
found 11 hours ago
Select Delta flight, departing Sun, 16 Aug from St. Louis to San Francisco, returning Thu, 20 Aug, priced at AU$636 found 11 hours ago
Alaska Airlines
Tue, 25 Aug - Mon, 31 Aug
STL
St. Louis
SFO
San Francisco
AU$641 Return, found 3 days ago
AU$641
Return
found 3 days ago
Select Alaska Airlines flight, departing Tue, 25 Aug from St. Louis to San Francisco, returning Mon, 31 Aug, priced at AU$641 found 3 days ago
Alaska Airlines
Sun, 16 Aug - Thu, 20 Aug
STL
St. Louis
SFO
San Francisco
AU$643 Return, found 11 hours ago
AU$643
Return
found 11 hours ago
Select Alaska Airlines flight, departing Sun, 16 Aug from St. Louis to San Francisco, returning Thu, 20 Aug, priced at AU$643 found 11 hours ago
Delta
Thu, 13 Aug - Mon, 17 Aug
STL
St. Louis
SFO
San Francisco
AU$649 Return, found 5 days ago
AU$649
Return
found 5 days ago
Select Delta flight, departing Thu, 13 Aug from St. Louis to San Francisco, returning Mon, 17 Aug, priced at AU$649 found 5 days ago
Delta
Thu, 13 Aug - Mon, 17 Aug
STL
St. Louis
SFO
San Francisco
AU$650 Return, found 5 days ago
AU$650
Return
found 5 days ago
Select Delta flight, departing Thu, 13 Aug from St. Louis to San Francisco, returning Mon, 17 Aug, priced at AU$650 found 5 days ago
American Airlines
Sun, 16 Aug - Thu, 20 Aug
STL
St. Louis
SFO
San Francisco
AU$674 Return, found 11 hours ago
AU$674
Return
found 11 hours ago
Select American Airlines flight, departing Sun, 16 Aug from St. Louis to San Francisco, returning Thu, 20 Aug, priced at AU$674 found 11 hours ago
Delta
Sun, 16 Aug - Thu, 20 Aug
STL
St. Louis
SFO
San Francisco
AU$676 Return, found 11 hours ago
AU$676
Return
found 11 hours ago
Select Delta flight, departing Sun, 16 Aug from St. Louis to San Francisco, returning Thu, 20 Aug, priced at AU$676 found 11 hours ago
Alaska Airlines
Sun, 16 Aug - Thu, 20 Aug
STL
St. Louis
SFO
San Francisco
AU$683 Return, found 11 hours ago
AU$683
Return
found 11 hours ago
Select Alaska Airlines flight, departing Sun, 16 Aug from St. Louis to San Francisco, returning Thu, 20 Aug, priced at AU$683 found 11 hours ago
United
Sun, 16 Aug - Thu, 20 Aug
STL
St. Louis
SFO
San Francisco
AU$708 Return, found 11 hours ago
AU$708
Return
found 11 hours ago
Select United flight, departing Sun, 16 Aug from St. Louis to San Francisco, returning Thu, 20 Aug, priced at AU$708 found 11 hours ago

Frequently asked questions

How much does a flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) cost?
You can find one-way and return flights from STL to SFO with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when STL to SFO ticket fares go up or down.
What is the cheapest month to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
If you're looking for the cheapest time to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.), September is typically your best bet. You can expect average return fares to be around AU$563 during this month. Other budget-friendly months for this route include August and October.
Which airlines fly direct from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
There are 2 airlines offering direct flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.). Here are the carriers:
  • United operates 10 direct flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) every week.
  • Southwest Airlines operates 8 direct flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) every week.
How do I find cheap flights from St. Louis, MO (STL) to San Francisco, CA (SFO)?
To find a cheap flight from St. Louis, MO (STL) to San Francisco, CA (SFO), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The best airline to fly with from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) will differ from traveler to traveler. If you like to fly early, Southwest Airlines offers early morning flights. If price is the most important factor, Southwest Airlines typically offers the lowest fares. Southwest Airlines offers the most daily flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The cheapest months to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) are typically September and October, with return flights averaging around AU$563. These months can be a great time to visit San Francisco as the summer crowds start to thin out, and you might find pleasant weather, offering a good balance of value and experience.
How many flights per day from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
You'll find approximately 3 nonstop flights per day from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.). For even more choices, look at flights that include layovers, as there are around 96 connecting flights per day. Some common connection points include O'Hare Intl. (ORD), Seattle - Tacoma Intl. (SEA), and Denver Intl. (DEN).
What is the earliest flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The earliest flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) typically departs around 5:00 AM. This service is operated by American Airlines. Please note that this is a seasonal service, active in January, November, and December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
You'll find the most flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) on a Friday, with around 76 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include Southwest Airlines, United, and American Airlines. Flight schedules are fairly consistent throughout the week, with Fridays offering only slightly more options compared to other weekdays.
What are the most popular departure times for flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
The most popular departure times for flights from Lambert-St. Louis Intl. (STL) to San Francisco Intl. (SFO) are in the morning, from 6am to 9am. Many major carriers, including Southwest Airlines, American Airlines and United, offer flights during this window. This timing works well for travelers who want to arrive in San Francisco early in the day, giving them more time to enjoy their destination.
How long does it take to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
A non-stop flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) typically takes around 4 hours 30 minutes. This route covers a distance of approximately 2,787 kilometres. If you opt for a one-stop flight, your travel time will be longer, usually around 8 hours. Flights with two or more stops will take even longer, averaging about 11 hours. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your journey.
Can you fly business or first class from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.)?
You can fly business class or first class between STL and SFO.Airlines that offer business class service on this route include:

  • Frontier Airlines
  • Delta

First class cabins are available on:

  • Alaska Airlines
  • Delta
  • United
  • American Airlines

How do I earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight with Expedia?
It's easy to earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for San Francisco, CA (SFO) from St. Louis, MO (STL)?
If you're planning to travel to San Francisco from Lambert-St. Louis Intl. (STL), you can fly directly into San Francisco Intl. (SFO). Some flights may connect through major hubs like Seattle - Tacoma Intl. (SEA), Love Field (DAL), or Sky Harbor Intl. (PHX) before reaching San Francisco. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) at the last minute?
Typically, booking a last minute flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package?
Securing a St. Louis, MO (STL-Lambert-St. Louis Intl.) to San Francisco, CA (SFO-San Francisco Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from St. Louis, MO (STL) to San Francisco, CA (SFO)?
If you booked your St. Louis, MO (STL) to San Francisco, CA (SFO) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
San Francisco Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, United
Return price
AU$635
Distance
2771 km
Average flight time
3 hours 5 mins

Book with confidence

Your quick guide to flights from St. Louis to San Francisco

Pick up great flights from St. Louis to San Francisco

With Expedia, you have your pick of flights a day with 20 airlines covering flights from St. Louis to San Francisco. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from St. Louis to San Francisco that take around hours.

Find cheap flights from St. Louis to San Francisco

From the great flight deals with prices currently ranging from AU$636 to AU$708, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from St. Louis to San Francisco around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to San Francisco is normally in August.

Reasons to book your flight from St. Louis to San Francisco with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from St. Louis to San Francisco across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to San Francisco right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from St. Louis to San Francisco

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*Available to Expedia members.