Cheap Flights from Panama City (PTY) to Chicago (ORD)

View AU$559 flight on Sat, 16 May 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Chicago O'Hare International Airport (ORD)

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Cheap Flights from Panama City (PTY) to Chicago (ORD)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$1,695 Return, found 10 hours ago
AU$1,695
Return
found 10 hours ago
Select Delta flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$1,695 found 10 hours ago
United
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$1,932 Return, found 10 hours ago
AU$1,932
Return
found 10 hours ago
Select United flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$1,932 found 10 hours ago
United
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$2,022 Return, found 10 hours ago
AU$2,022
Return
found 10 hours ago
Select United flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$2,022 found 10 hours ago
United
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$2,078 Return, found 10 hours ago
AU$2,078
Return
found 10 hours ago
Select United flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$2,078 found 10 hours ago
Delta
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$2,124 Return, found 10 hours ago
AU$2,124
Return
found 10 hours ago
Select Delta flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$2,124 found 10 hours ago
Delta
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$2,130 Return, found 10 hours ago
AU$2,130
Return
found 10 hours ago
Select Delta flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$2,130 found 10 hours ago
United
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$2,169 Return, found 10 hours ago
AU$2,169
Return
found 10 hours ago
Select United flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$2,169 found 10 hours ago
Copa
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$2,306 Return, found 10 hours ago
AU$2,306
Return
found 10 hours ago
Select Copa flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$2,306 found 10 hours ago
Aeromexico
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$2,398 Return, found 10 hours ago
AU$2,398
Return
found 10 hours ago
Select Aeromexico flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$2,398 found 10 hours ago
avianca
Fri, 1 Jan - Sat, 2 Jan
PTY
Panama City
ORD
Chicago
AU$2,804 Return, found 10 hours ago
AU$2,804
Return
found 10 hours ago
Select avianca flight, departing Fri, 1 Jan from Panama City to Chicago, returning Sat, 2 Jan, priced at AU$2,804 found 10 hours ago

Frequently asked questions

What is the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
September is typically the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.), with average return fares of approximately 728 AUD. This is about 16% lower than the average price throughout the year. September often sees lower prices as the summer travel rush ends and before the holiday season begins, leading to reduced demand. Other cheap months to fly from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) include March and June.
Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
Enter PTY to ORD and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
The best airline to fly with from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) will differ from traveller to traveller. If you like to fly early, CM offers early morning flights. If price is the most important factor, CM typically offers the lowest fares. CM offers the most daily flights from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
The best time to fly from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) is typically September or June. These months offer the most budget-friendly options, with average return flights around 728 AUD. While we don't have specific popularity data for these months, choosing a time with lower prices often means you'll find good availability and potentially more flexible schedules. This information is based on booking data from the past year.
How many flights per day from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
There are approximately 2 nonstop flights per day from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.). For even more choice, look at flights that include layovers, as there are around 39 connecting flights per day. Some common connection points include El Dorado Intl. (BOG), George Bush Intercontinental (IAH), and Miami Intl. (MIA).
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
The earliest flight from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) typically departs at approximately 2:55 AM local time, operated by Avianca. This is a seasonal service active in January, February, March, October, November, and December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
You'll typically find the most flights from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) on a Tuesday, with around 34 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Copa Airlines, United Airlines, and Avianca.
What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) are in the early morning, from 6am to 9am. Around 28% of passengers reckon this time's best. Copa Airlines and United Airlines offer flights during this window. Many travelers prefer these early flights as they allow you to arrive at your destination with plenty of time to start your day.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
A nonstop flight from PTY to ORD typically takes around 5 hours 50 minutes, covering approximately 2,332 miles. Connecting flights on this route usually add 3 hours 30 minutes to your travel time. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
Select the "Business class" and "First class" filters when looking for PTY to ORD flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) flight with Expedia?
It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Chicago from Tocumen Intl. (PTY)?
When traveling from Tocumen Intl. (PTY) to Chicago, you can fly into Midway Intl. (MDW) and O'Hare Intl. (ORD). Some flights may connect through major hubs like Mexico City Intl. (MEX), General Mariano Escobedo Intl. (MTY) before reaching Chicago. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) at the last minute?
Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) flight and hotel package?
Securing a Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.)?
If you booked your Panama City (PTY-Tocumen Intl.) to Chicago, IL (ORD-O'Hare Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
O'Hare Intl.
Return price
AU$1,694
Distance
3731 km
Average flight time
5 hours 53 mins

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Your quick guide to flights from Panama City to Chicago

Pick up great flights from Panama City to Chicago

With Expedia, you have your pick of flights a day with 20 airlines covering flights from Panama City to Chicago. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Panama City to Chicago that take around hours.

Find cheap flights from Panama City to Chicago

From the great flight deals with prices currently ranging from AU$1,695 to AU$2,804, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Panama City to Chicago around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Chicago is normally in January.

Reasons to book your flight from Panama City to Chicago with Expedia

Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Panama City to Chicago across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Chicago right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.

Your quick guide to flights from Panama City to Chicago

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