Cheap flights from Des Moines to Santa Cruz Island

View AU$1,134 flight on Wed, 3 Sep. 2025Opens in a new window

Popular airlines from Des Moines to Santa Cruz Island

  • Jetstar

    Jetstar

  • Qantas Airways

    Qantas Airways

  • Virgin Australia

    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Des Moines (DSM) to Santa Cruz Island (GPS)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, 3 Sep. - Wed, 10 Sep.
DSM
Des Moines
GPS
Santa Cruz Island
AU$2,005 Return, found 3 days ago
AU$2,005
Return
found 3 days ago
Select United flight, departing Wed, 3 Sep. from Des Moines to Santa Cruz Island, returning Wed, 10 Sep., priced at AU$2,005 found 3 days ago
United
Wed, 3 Sep. - Wed, 10 Sep.
DSM
Des Moines
GPS
Santa Cruz Island
AU$2,245 Return, found 3 days ago
AU$2,245
Return
found 3 days ago
Select United flight, departing Wed, 3 Sep. from Des Moines to Santa Cruz Island, returning Wed, 10 Sep., priced at AU$2,245 found 3 days ago
United
Wed, 3 Sep. - Wed, 10 Sep.
DSM
Des Moines
GPS
Santa Cruz Island
AU$2,593 Return, found 3 days ago
AU$2,593
Return
found 3 days ago
Select United flight, departing Wed, 3 Sep. from Des Moines to Santa Cruz Island, returning Wed, 10 Sep., priced at AU$2,593 found 3 days ago
United
Wed, 3 Sep. - Wed, 10 Sep.
DSM
Des Moines
GPS
Santa Cruz Island
AU$2,646 Return, found 3 days ago
AU$2,646
Return
found 3 days ago
Select United flight, departing Wed, 3 Sep. from Des Moines to Santa Cruz Island, returning Wed, 10 Sep., priced at AU$2,646 found 3 days ago
Delta
Sun, 31 Aug. - Sun, 7 Sep.
DSM
Des Moines
GPS
Santa Cruz Island
AU$2,718 Return, found 6 days ago
AU$2,718
Return
found 6 days ago
Select Delta flight, departing Sun, 31 Aug. from Des Moines to Santa Cruz Island, returning Sun, 7 Sep., priced at AU$2,718 found 6 days ago
LATAM Airlines Group
Wed, 3 Sep. - Wed, 10 Sep.
DSM
Des Moines
GPS
Santa Cruz Island
AU$2,742 Return, found 3 days ago
AU$2,742
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, 3 Sep. from Des Moines to Santa Cruz Island, returning Wed, 10 Sep., priced at AU$2,742 found 3 days ago
United
Wed, 3 Sep. - Wed, 10 Sep.
DSM
Des Moines
GPS
Santa Cruz Island
AU$2,832 Return, found 3 days ago
AU$2,832
Return
found 3 days ago
Select United flight, departing Wed, 3 Sep. from Des Moines to Santa Cruz Island, returning Wed, 10 Sep., priced at AU$2,832 found 3 days ago
United
Sun, 31 Aug. - Sun, 7 Sep.
DSM
Des Moines
GPS
Santa Cruz Island
AU$2,870 Return, found 6 days ago
AU$2,870
Return
found 6 days ago
Select United flight, departing Sun, 31 Aug. from Des Moines to Santa Cruz Island, returning Sun, 7 Sep., priced at AU$2,870 found 6 days ago
*Available to Expedia members.