Cheap flights from Santiago to San Diego

View AU$429 flight on Fri, 29 Aug. 2025Opens in a new window

Popular airlines from Santiago to San Diego

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Santiago (SCL) to San Diego (SAN)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Fri, 29 Aug. - Fri, 5 Sep.
SCL
Santiago
SAN
San Diego
AU$764 Return, found 3 days ago
AU$764
Return
found 3 days ago
Select Copa flight, departing Fri, 29 Aug. from Santiago to San Diego, returning Fri, 5 Sep., priced at AU$764 found 3 days ago
Copa
Fri, 29 Aug. - Fri, 5 Sep.
SCL
Santiago
SAN
San Diego
AU$839 Return, found 3 days ago
AU$839
Return
found 3 days ago
Select Copa flight, departing Fri, 29 Aug. from Santiago to San Diego, returning Fri, 5 Sep., priced at AU$839 found 3 days ago
Copa
Fri, 29 Aug. - Fri, 5 Sep.
SCL
Santiago
SAN
San Diego
AU$869 Return, found 3 days ago
AU$869
Return
found 3 days ago
Select Copa flight, departing Fri, 29 Aug. from Santiago to San Diego, returning Fri, 5 Sep., priced at AU$869 found 3 days ago
Copa
Fri, 29 Aug. - Fri, 5 Sep.
SCL
Santiago
SAN
San Diego
AU$912 Return, found 3 days ago
AU$912
Return
found 3 days ago
Select Copa flight, departing Fri, 29 Aug. from Santiago to San Diego, returning Fri, 5 Sep., priced at AU$912 found 3 days ago
Delta
Fri, 29 Aug. - Fri, 5 Sep.
SCL
Santiago
SAN
San Diego
AU$1,332 Return, found 3 days ago
AU$1,332
Return
found 3 days ago
Select Delta flight, departing Fri, 29 Aug. from Santiago to San Diego, returning Fri, 5 Sep., priced at AU$1,332 found 3 days ago
LATAM Airlines Group
Fri, 29 Aug. - Fri, 5 Sep.
SCL
Santiago
SAN
San Diego
AU$1,444 Return, found 3 days ago
AU$1,444
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Fri, 29 Aug. from Santiago to San Diego, returning Fri, 5 Sep., priced at AU$1,444 found 3 days ago
*Available to Expedia members.