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Our top choices for Williamston hotels

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1000)
"The room was exceptionally clean and very spacious."
United States
Edward
Travelling with partner
The price is AU$201
includes taxes & fees
30 Dec - 31 Dec
Lakeside Lodge Clemson

Comfort Suites Simpsonville - Greenville

Comfort Suites Simpsonville - Greenville
2.5 star property
Simpsonville
8.2 out of 10, Very good, (775)
"the bed was very comfortable"
United States
Shelly
Travelling for leisure
The price is AU$162
includes taxes & fees
2 Jan - 3 Jan 2026
Comfort Suites Simpsonville - Greenville

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (668)
"Very quiet with great workout facility"
United States
Mark
Travelling for leisure
The price is AU$199
includes taxes & fees
15 Jan - 16 Jan 2026
Hampton Inn & Suites Seneca-Clemson Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (800)
"Clean rooms, friendly staff, great game room/hang out space."
United States
karen
Travelling for leisure
The price is AU$163
includes taxes & fees
25 Jan - 26 Jan 2026
Tru by Hilton Seneca Clemson

Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
2.5 star property
Simpsonville
9.4 out of 10, Exceptional, (514)
"We had a great experience staying here, from the outdoor pool to the very convenient complementary breakfast."
United States
parker
Travelling for leisure
The price is AU$219
includes taxes & fees
30 Dec - 31 Dec
Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Nice Room , friendly staff , nice and clean breakfast bar!"
United States
Mandy
Travelling with family
The price is AU$197
includes taxes & fees
2 Jan - 3 Jan 2026
Fairfield Inn & Suites Seneca Clemson Univ Area

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (642)
"the hotel's cleanliness was impeccable"
United States
Crystal
Travelling for leisure
The price is AU$146
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Seneca-Clemson

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (665)
"The hotel room is good size with comfortable bedding."
United States
Sarah
Travelling with family
The price is AU$129
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn Seneca Clemson Area US-123

Fairfield Inn & Suites by Marriott Greenville Simpsonville

Fairfield Inn & Suites by Marriott Greenville Simpsonville
2.5 star property
Simpsonville
9.2 out of 10, Wonderful, (671)
"Friendly staff and clean room"
United States
Santosh
Travelling for leisure
The price is AU$195
includes taxes & fees
30 Dec - 31 Dec
Fairfield Inn & Suites by Marriott Greenville Simpsonville

Mint House Greenville - Downtown

Mint House Greenville - Downtown
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (781)
"This was a great place to stay in a very convenient and pleasant location."
United States
Stephanie
Travelling for business
Mint House Greenville - Downtown

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (523)
"Overall, great stay!"
United States
Lynn
The price is AU$197
includes taxes & fees
30 Dec - 31 Dec
Courtyard Marriott Clemson

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very good, (1002)
"Hotel was very nice and clean."
United States
Albert
Inn @ Clemson

Hampton Inn Simpsonville

Hampton Inn Simpsonville
2.5 star property
Simpsonville
8.8 out of 10, Excellent, (593)
"Very clean rooms and amazing staff"
United States
John C
Travelling for business
The price is AU$206
includes taxes & fees
6 Jan - 7 Jan 2026
Hampton Inn Simpsonville

Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1002)
"Wonderful spacious room, very clean, AMAZING STAFF!"
United States
Bernard
Travelling for leisure
The price is AU$200
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites by Hilton Greenville Downtown

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
3.5 star property
Greenville
9.0 out of 10, Wonderful, (1009)
"Room was spotless and graciously large"
United States
Rodney
Travelling with partner
The price is AU$161
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites Greenville Golf Resort & Conference Center

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (757)
"Bed and pillows were nice and comfy."
United States
Gregory
Travelling solo
The price is AU$124
includes taxes & fees
30 Dec - 31 Dec
Baymont by Wyndham Easley/Greenville

Days Inn by Wyndham Simpsonville

Days Inn by Wyndham Simpsonville
2.0 star property
Simpsonville
7.2 out of 10, Good, (416)
"The rooms were cleaned well"
United States
John
Travelling for leisure and business
The price is AU$121
includes taxes & fees
23 Jan - 24 Jan 2026
Days Inn by Wyndham Simpsonville

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (389)
"Extremely quiet and newly refurbished comfortable large King bed"
United States
Jack
Travelling for leisure
The price is AU$86
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn & Suites Easley - Greenville

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
3.0 star property
Greenville
8.6 out of 10, Excellent, (81)
"The hotel was extremely clean"
United States
Jonaa
Travelling with family
The price is AU$126
includes taxes & fees
31 Dec - 1 Jan 2026
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (558)
"Wonderful room, spacious and clean."
United States
Kristi
Travelling for business
The Abernathy of Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Williamston attractions

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Head to sights like Williamston Town Hall and Anderson Motor Speedway as you discover Williamston.

View of live oak trees and bridge in Palmetto Bluff near Bluffton, South Carolina, USA.

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Frequently asked questions

What's the best place for a stay in Williamston?
Located 18.3 mi (29.4 km) from the heart of Williamston, Hilton Greenville is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Homewood Suites by Hilton Greenville Downtown and Embassy Suites Greenville Golf Resort & Conference Center. See all available top hotels, or vacation rentals in Williamston.
What are some of the best holiday rentals that Williamston has to offer?
Upscale Artsy Bungalow-Walk away to Unity Park: This holiday home rental outside of Williamston offers a fireplace, a BBQ and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a stovetop and a microwave, so that you can cook with friends or family. See all vacation rentals in Williamston.
If I need to cancel my hotel reservation in Williamston, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Williamston.
What's it like staying in Williamston?
Travellers to Williamston will find plenty to explore and enjoy. There are 1361 hotels and other accommodation options in the surrounding area. Find out more about Williamston.
What is there to see in Williamston?
Favourite places to visit include Williamston Town Hall, Anderson Motor Speedway and Town Square Center. Additionally, you might want to add Saluda Valley Golf Course to your itinerary. Take a look at what more there is to see and do in Expedia's Williamston guide.
What's the seasonal weather like in Williamston?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Williamston is 1509 mm.

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