A bench, a bicycle, and a lake surrounded by trees.

Business Hotels & Resorts in Upstate South Carolina from AU$112

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Check availability on Upstate South Carolina Business Hotels

Tonight
10 Oct - 11 Oct
Tomorrow
11 Oct - 12 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Upstate South Carolina business-friendly hotels

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.
A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.
A pool area with lounge chairs and a sign for Best Western Plus.
A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

1. Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
Greenville
United States
Stephanie
AU$123
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus Greenville I-385 Inn & Suites
A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.
A large hotel with a central courtyard, surrounded by manicured lawns and trees.
An outdoor patio area with tables and chairs, a covered seating area, and a building in the background labeled "Embassy Suites."
A spacious lobby with multiple seating areas, a glass railing overlooking a green space, and a modern interior design.

2. Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
Greenville
United States
Ethan
AU$172
includes taxes & fees
1 Nov - 2 Nov
Embassy Suites Greenville Golf Resort & Conference Center
An outdoor patio area with a fire feature, wicker furniture, and potted plants.
A row of Tesla electric vehicle charging stations.
A Hilton Garden Inn with a central entrance, multiple floors, and a brick facade.
A conference room with a large table, green chairs, a sofa, and large windows offering a view of trees and a parking lot.

3. Hilton Garden Inn Greenville

Hilton Garden Inn Greenville
Greenville
United States
Leroy
AU$158
includes taxes & fees
31 Oct - 1 Nov
Hilton Garden Inn Greenville
A modern kitchen with hanging light fixtures and bar seating.
A hotel patio with outdoor seating, stone pillars, and a modern building in the background.
A modern lobby with a curved reception desk, comfortable seating, and a large wall-mounted TV.
A modern bar area with a central island, bar stools, and overhead lighting.

4. DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
Greenville
United States
Jeffery
AU$181
includes taxes & fees
18 Oct - 19 Oct
DoubleTree by Hilton Greenville Woodruff Road
An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a red accent wall.
A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.
A fitness center with treadmills, elliptical machines, and a red exercise ball.

5. Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
Greenville
United States
Kara
AU$181
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites Greenville
A hotel with a stone facade, multiple windows, and a sign indicating it's a Wyndham hotel.
A modern kitchen with a granite countertop, a built-in grill, a microwave, and a coffee maker. There are two framed artworks on the wall and a refrigerator with a built-in ice maker.
A hotel room with a bed, a television, a window with curtains, and a wardrobe.
A compact living space with a kitchenette, a flat-screen TV, a sofa, and a bed with a patterned cover.

6. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Greenville
United States
Terry
AU$112
includes taxes & fees
1 Nov - 2 Nov
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
A modern hotel lobby with a bar area, seating, and a patterned floor.
A hotel entrance with a welcoming sign, a covered walkway, and a landscaped area with benches and flowers.
A modern living room with a sofa, armchairs, a coffee table, and a patterned rug.
A hotel room with two beds, a desk, a TV, and a large window with curtains.

7. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Greenville
United States
George
AU$151
includes taxes & fees
8 Nov - 9 Nov
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
A modern hotel room with a large bed, a desk, and a seating area with chairs and a table.
A hotel room with a large bed, a television on a dresser, a nightstand with a lamp, and a window with curtains.
A hotel pool area with lounge chairs, a flag, and a sunset view.
A snack and beverage display with various snacks and drinks.

8. Hampton Inn Greenville I-385 - Woodruff Rd.

Hampton Inn Greenville I-385 - Woodruff Rd.
Greenville
United States
Stephen
AU$165
includes taxes & fees
29 Oct - 30 Oct
Hampton Inn Greenville I-385 - Woodruff Rd.
A modern outdoor seating area with a glass-top coffee table, blue sofas, and orange patterned cushions.
A modern lobby with a blue sofa, teal armchairs, hanging lights, and a seating area with round chairs.
A modern lobby with a reception desk, seating areas, and a large window offering a view.
A snack bar with a variety of packaged foods and beverages, a refrigerated display case, and a counter with a sign that reads 'This and that and then some.'

9. Tru by Hilton Greenville Woodruff Road

Tru by Hilton Greenville Woodruff Road
Greenville
United States
semhar
AU$169
includes taxes & fees
1 Nov - 2 Nov
Tru by Hilton Greenville Woodruff Road
A spacious hotel lobby with a central bar area, seating arrangements, and large windows providing natural light.
A hotel room with a bed, desk, chair, TV, and a window with a geometric pattern.
A modern lounge area with green upholstered seating, a coffee table, and pendant lighting.
A conference room with a large flat-screen TV, multiple tables with chairs, and water bottles on each table.

10. Holiday Inn Greenville - Woodruff Road by IHG

Holiday Inn Greenville - Woodruff Road by IHG
Greenville
United States
Diane
AU$162
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Greenville - Woodruff Road by IHG
View all properties

Top Upstate South Carolina Hotel Reviews

Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

10/10 Excellent
"The room was very clean. Staff was very helpful when our key did not work. The hotel was under renovation. They did a great job at keeping it clean and quiet. My husband and granddaughter had the breakfast. They liked it. Parking was tight due to the construction. Otherwise, good. We would stay there again. Highly recommend staying here."
Kevin 4-night trip
Posted 5 hours ago
Hyatt Place Greenville/Haywood
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

10/10 Excellent
"Clean room, very convenient to 385, great breakfast, nice staff, plenty of parking."
Paul 1-night trip
Posted 15 hours ago
Comfort Inn Greenville - Haywood Mall
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

10/10 Excellent
"The rooms are clean and the hotel staff are friendly, Plenty of parking, Restaurants in walking distance and shopping. Hotel has been remodeled also 👍"
Terry 1-night trip
Posted 17 hours ago
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

10/10 Excellent
"Very clean"
Brittany 1-night trip
Posted 17 hours ago
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Frequently asked questions

How much do business-friendly hotels in Upstate South Carolina cost?
Prepare to pay between AU$112 and AU$181 per night for business-friendly hotels in Upstate South Carolina. Epic deals on stays that are suitable for work-related travellers are a click away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Upstate South Carolina?
When your job takes you on the road in Upstate South Carolina, there are 144 business-friendly hotels to choose from.
What is there to do in Upstate South Carolina near my business-friendly hotel?
There are tons of things to see and do in Upstate South Carolina. If you're off to Greenville, check out Greenville Zoo, The Children's Museum of the Upstate and Greenville County Museum of Art. Planning a stay in Spartanburg? Spartanburg Regional History Museum, Wofford College and Spartanburg Memorial Auditorium are among the top sights in this city.

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