A bench, a bicycle, and a lake surrounded by trees.

Business Hotels & Resorts in Upstate South Carolina from AU$108

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Check availability on Upstate South Carolina Business Hotels

Tonight
23 Aug - 24 Aug
Tomorrow
24 Aug - 25 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sept - 6 Sept

Our top choices for Upstate South Carolina business-friendly hotels

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.
A pool area with lounge chairs and a sign for Best Western Plus.
A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.
A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

1. Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
Greenville
United States
Nancy
AU$127
includes taxes & fees
30 Aug - 31 Aug
Best Western Plus Greenville I-385 Inn & Suites
A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.
A gym with treadmills, ellipticals, and a pool view.
An indoor swimming pool with lounge chairs and potted plants.
An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

2. Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
Greenville
United States
Robert
AU$154
includes taxes & fees
30 Aug - 31 Aug
Embassy Suites Greenville Golf Resort & Conference Center
A multi-story hotel with a modern design, featuring a prominent 'La Quinta' sign, a parking lot, and a landscaped entrance area.
A modern living room with a fireplace, a flat-screen TV, and comfortable seating.
A La Quinta hotel with a covered outdoor seating area, stone pillars, and a parking lot.
A modern kitchen with a refrigerator, coffee machine, and various food items.

3. La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Greenville
United States
Cole
AU$117
includes taxes & fees
26 Aug - 27 Aug
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.
A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a red accent wall.
A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

4. Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
Greenville
United States
Gohan
AU$176
includes taxes & fees
30 Aug - 31 Aug
Drury Inn & Suites Greenville
A modern hotel room with a large bed, a separate bathroom with a bathtub, a nightstand, a lamp, and a wall-mounted artwork.
A reception area with two beige armchairs, a glass-top table, and a vibrant geometric wall art.
A Days Inn by Wyndham hotel with a covered entrance, multiple windows, and a parking area with cars.
A reception desk with a stone facade, a peacock wall decoration, and a large potted plant.

5. Days Inn by Wyndham Greenville South/Mauldin

Days Inn by Wyndham Greenville South/Mauldin
Mauldin
United States
Martel
AU$108
includes taxes & fees
13 Sept - 14 Sept
Days Inn by Wyndham Greenville South/Mauldin
A modern lobby with a reception desk, seating area, and a television screen.
A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.
A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.
A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

6. Best Western Spartanburg I-26

Best Western Spartanburg I-26
Spartanburg
United States
Francisco
AU$130
includes taxes & fees
29 Aug - 30 Aug
Best Western Spartanburg I-26
A Microtel hotel with a stone facade, multiple windows, and a central entrance.
A room with a wall-mounted ATM, decorative wall panels, a window with red curtains, and a tiled floor.

7. Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
Greenville
United States
Steven
AU$117
includes taxes & fees
7 Sept - 8 Sept
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd
A spacious lobby with modern furniture, a chandelier, and potted plants.
An outdoor seating area with tables and chairs, potted plants, and a modern building facade.
A bar with a white countertop, multiple bar stools, and shelves stocked with bottles.

8. Hilton Greenville

Hilton Greenville
Greenville
United States
Gildardo
AU$162
includes taxes & fees
4 Sept - 5 Sept
Hilton Greenville
A Holiday Inn Express building with a modern design, featuring a covered parking area and multiple entry points.
A modern building entrance with stone pillars, a bench, and a glass door leading inside.
A modern indoor seating area with high tables, cushioned seating, and a large TV screen.
An outdoor patio area with tables and chairs, a building with large windows, and a stone pillar.

9. Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG

Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
Simpsonville
United States
Alicia
AU$199
includes taxes & fees
28 Aug - 29 Aug
Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
A modern kitchen with hanging light fixtures and bar seating.
A modern bar area with a central island, bar stools, and overhead lighting.
A hotel patio with outdoor seating, stone pillars, and a modern building in the background.
A modern lobby with a curved reception desk, comfortable seating, and a large wall-mounted TV.

10. DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
Greenville
United States
JOANNA
AU$176
includes taxes & fees
30 Aug - 31 Aug
DoubleTree by Hilton Greenville Woodruff Road
View all properties

Top Upstate South Carolina Hotel Reviews

Hyatt Regency Greenville

Hyatt Regency Greenville

8/10 Good
"During both check in and check out we had lost luggage and valet related issues. During check in, our bags were misplaced and during check out their valet after the 6am start time, no one was in attendance to retrieve our car, making us late for a meeting."
Brian 1-night trip
Posted 12 hours ago
Hyatt Regency Greenville
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

8/10 Good
"Close to campus."
Christopher 2-night trip
Posted 13 hours ago
Comfort Inn & Suites Clemson - University Area
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent
"X"
Scott 1-night trip
Posted 13 hours ago
Best Western Plus Greenville I-385 Inn & Suites
AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg

10/10 Excellent
"This is a first class property. Verry clean Verry modern our stay was short but overall impressive I would definitely satay there again"
Christopher 1-night trip
Posted 18 hours ago
AC Hotel by Marriott Spartanburg
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

10/10 Excellent
"Comfortable staying"
Michael 3-night trip
Posted 2 days ago
Hyatt Place Greenville/Haywood
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

10/10 Excellent
"The staff was amazing! And I loved the spacious room - very clean."
Diane 1-night trip
Posted 3 days ago
Comfort Suites At WestGate Mall
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent
"This was the most enjoyable stay I’ve had in Clemson! Everything was great. I will stay here again next year!"
James 2-night trip
Posted 5 days ago
Best Western Plus Clemson Hotel & Conference Center

Frequently asked questions

How much do business-friendly hotels in Upstate South Carolina cost?
Prepare to pay between AU$108 and AU$199 per night for business-friendly hotels in Upstate South Carolina. Epic deals on stays that are suitable for work-related travellers are a click away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Upstate South Carolina?
When your job takes you on the road in Upstate South Carolina, there are 144 business-friendly hotels to choose from.
What is there to do in Upstate South Carolina near my business-friendly hotel?
There are tons of things to see and do in Upstate South Carolina. If you're off to Greenville, check out Greenville Zoo, The Children's Museum of the Upstate and Greenville County Museum of Art. Planning a stay in Spartanburg? Spartanburg Regional History Museum, Wofford College and Spartanburg Memorial Auditorium are among the top sights in this city.

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