Default HTG hotel image

Top Hotels Near Substance in Las Vegas from AU$58

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Substance hotels

Circa Resort & Casino – Adults Only

Circa Resort & Casino – Adults Only
4.5 star property
Downtown Las Vegas, 0.5 km from Substance
9.4 out of 10, Exceptional, (5,681 reviews)
"We had a great stay!"
United States
Mallory
The price is AU$263
includes taxes & fees
19 June - 20 June
Circa Resort & Casino – Adults Only

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
Arts District, 1.4 km from Substance
9.4 out of 10, Exceptional, (130 reviews)
"Excellent property "
United States
Leroy
The price is AU$222
includes taxes & fees
21 June - 22 June
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

Main Street Station Hotel, Casino and Brewery

Main Street Station Hotel, Casino and Brewery
2.5 star property
Downtown Las Vegas, 0.6 km from Substance
9.0 out of 10, Wonderful, (3,378 reviews)
"Amazing stay!"
United States
Juneda
The price is AU$92
includes taxes & fees
30 June - 1 July
Main Street Station Hotel, Casino and Brewery

Element by Marriott Las Vegas Symphony Park

Element by Marriott Las Vegas Symphony Park
3.0 star property
1.2 km from Substance
9.2 out of 10, Wonderful, (111 reviews)
"very clean room, easy access, good breakfast, good parking"
United States
Joanna
The price is AU$213
includes taxes & fees
30 June - 1 July
Element by Marriott Las Vegas Symphony Park

Four Queens Hotel and Casino

Four Queens Hotel and Casino
3.5 star property
Downtown Las Vegas, 0.3 km from Substance
8.6 out of 10, Excellent, (7,196 reviews)
"Great stay"
United States
Ronald
The price is AU$94
includes taxes & fees
8 July - 9 July
Four Queens Hotel and Casino

El Cortez Hotel and Casino - 21 and Over

El Cortez Hotel and Casino - 21 and Over
3.0 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very good, (7,265 reviews)
"Always a great stay"
United States
Sharon
The price is AU$109
includes taxes & fees
15 July - 16 July
El Cortez Hotel and Casino - 21 and Over

AC Hotel by Marriott Las Vegas Symphony Park

AC Hotel by Marriott Las Vegas Symphony Park
3.0 star property
1.2 km from Substance
8.8 out of 10, Excellent, (218 reviews)
"Beautiful hotel, great location! Would definitely stay here again."
United States
Luis Alberto
The price is AU$200
includes taxes & fees
21 June - 22 June
AC Hotel by Marriott Las Vegas Symphony Park

the D Las Vegas

the D Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very good, (7,523 reviews)
"Clean rooms, friendly staff, great location"
United States
Jacqueline
The price is AU$107
includes taxes & fees
28 June - 29 June
the D Las Vegas

Downtown Grand Las Vegas

Downtown Grand Las Vegas
3.5 star property
Downtown Las Vegas, 0.2 km from Substance
8.4 out of 10, Very good, (9,984 reviews)
"Great absolutely would stay there again"
United States
Michael
The price is AU$132
includes taxes & fees
24 June - 25 June
Downtown Grand Las Vegas

Hotel Apache

Hotel Apache
3.5 star property
Downtown Las Vegas, 0.4 km from Substance
8.4 out of 10, Very good, (1,143 reviews)
"front desk was amazing and casino had great drink service"
Canada
Darren
The price is AU$62
includes taxes & fees
9 July - 10 July
Hotel Apache

Golden Nugget Las Vegas Hotel & Casino

Golden Nugget Las Vegas Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.4 km from Substance
8.2 out of 10, Very good, (13,560 reviews)
"Our stay was fantastic!"
United States
Cheyenne
The price is AU$120
includes taxes & fees
29 June - 30 June
Golden Nugget Las Vegas Hotel & Casino

Plaza Hotel & Casino

Plaza Hotel & Casino
4.0 star property
Downtown Las Vegas, 0.6 km from Substance
8.2 out of 10, Very good, (5,307 reviews)
"Location, Food, Staff......All Good"
United States
Fred
The price is AU$111
includes taxes & fees
23 June - 24 June
Plaza Hotel & Casino

Fremont Hotel & Casino

Fremont Hotel & Casino
3.0 star property
Downtown Las Vegas, 0.3 km from Substance
8.8 out of 10, Excellent, (4,361 reviews)
"Great place to stay."
United States
John
The price is AU$95
includes taxes & fees
30 June - 1 July
Fremont Hotel & Casino

Oasis at Gold Spike

Oasis at Gold Spike
3.5 star property
Downtown Las Vegas, < 0.1 km from Substance
8.0 out of 10, Very good, (2,284 reviews)
"Very cozy and fun place to stay! "
United States
Alexis
The price is AU$81
includes taxes & fees
17 June - 18 June
Oasis at Gold Spike

Desert Moon Motel

Desert Moon Motel
2.5 star property
Downtown Las Vegas, 1.5 km from Substance
8.4 out of 10, Very good, (499 reviews)
"It may not seem like much from the outside but the rooms are really nice with a lot of amenities. Clean and comfy beds and a nice tv."
United States
maricsa
The price is AU$79
includes taxes & fees
15 July - 16 July
Desert Moon Motel

Downtowner Boutique Hotel

Downtowner Boutique Hotel
3.0 star property
Downtown Las Vegas, 0.4 km from Substance
7.6 out of 10, Good, (44 reviews)
"Great for families, I wish they'd do something with the pool area...its needs some shade."
United States
Cheryl
The price is AU$88
includes taxes & fees
17 June - 18 June
Downtowner Boutique Hotel

Golden Gate Hotel and Casino

Golden Gate Hotel and Casino
2.5 star property
Downtown Las Vegas, 0.5 km from Substance
7.6 out of 10, Good, (1,072 reviews)
"Fun stay"
United States
Thomas
The price is AU$101
includes taxes & fees
17 June - 18 June
Golden Gate Hotel and Casino

Bposhtels Las Vegas

Bposhtels Las Vegas
2.5 star property
1.8 km from Substance
7.6 out of 10, Good, (293 reviews)
"Clean and safe. Would definitely stay there again."
United States
Hugo
The price is AU$58
includes taxes & fees
21 June - 22 June
Bposhtels Las Vegas

The STRAT Hotel, Casino & Tower

The STRAT Hotel, Casino & Tower
4.0 star property
Las Vegas Strip, 2.9 km from Substance
7.6 out of 10, Good, (23,603 reviews)
"Great place to stay!"
United States
Ronald
The price is AU$101
includes taxes & fees
1 July - 2 July
The STRAT Hotel, Casino & Tower

Thunderbird Hotel

Thunderbird Hotel
2.5 star property
Gateway District, 1.8 km from Substance
7.2 out of 10, Good, (1,004 reviews)
"Clean and spacious and quiet room easy parking"
United States
Chandramouli
The price is AU$92
includes taxes & fees
17 June - 18 June
Thunderbird Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Substance

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Circa Resort & Casino – Adults Only
4.5 star property
9.4
Exceptional
5,681 reviews
View
Exterior
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over
4.0 star property
9.4
Exceptional
130 reviews
View
Daily buffet breakfast for a fee
Main Street Station Hotel, Casino and Brewery
2.5 star property
9.0
Wonderful
3,378 reviews
View
View from property
Element by Marriott Las Vegas Symphony Park
3.0 star property
9.2
Wonderful
111 reviews
View
In-room safe, blackout curtains, iron/ironing board, free WiFi
Four Queens Hotel and Casino
3.5 star property
8.6
Excellent
7,196 reviews
View

Top Substance Hotel Reviews

Hotels near other Substance attractions

Frequently asked questions

What's the area like around Substance?
Substance is located in Las Vegas. This welcoming area is known for its array of dining options and bar scene. If you're looking for a convenient place to stay, take a look at the 174 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Substance?
Adjacent to Substance, Golden Nugget Las Vegas Hotel & Casino is one of the top choices for your stay based on our traveller data, and this resort offers 2 outdoor pools and a full-service spa. Other good options within a short distance include Downtown Grand Las Vegas and Fremont Hotel & Casino.
How many hotels will I be able to find close to Substance?
Expedia has 174 hotels and other accommodation options within a mile from Substance.
If I need to cancel the hotel reservation for my stay near Substance, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Substance.
What can I see and do near Substance?
You might want to spend some time browsing the exhibits at Mob Museum, The Neon Museum or Zak Bagans Haunted Museum. Old Las Vegas Mormon Fort State Historic Park, Harrison House and First AME Church are monuments to see when you're exploring the area around Substance. You can watch performances at Colosseum at Caesars Palace, Sphere and Dolby Live if you're interested in local theatre.