Downtown Clayton Travel Guide
Tourist Guide
Visit Downtown Clayton
Popular places to visit
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Washington University in St. Louis
Explore the campus of Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
Activities
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis: Museum of Illusions Entry Ticket
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Small Group Tour With Arch & River Cruise
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
St. Louis Premium Driving Tour with Boat Ride & Arch
Our pick of the best Downtown Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
Staff always pleasant
Reviewed on 2 Feb 2026
The Ritz-Carlton, St. Louis
Very courteo
Reviewed on 13 Jan 2026
AC Hotel St. Louis Clayton
My room was spotless and very well put together.
Reviewed on 9 Jan 2026
21C Museum Hotel St Louis
Hotel was very quiet and staff helpful and courteous. The coffee shop was great for coffee and breakfast and the rooms were clean with hot water and great water pressure. The only thing I would change was the mattress - bed was very firm, kind of felt like lying on a table. Gallery was a fun feature ...
Reviewed on 3 Feb 2026
Pear Tree Inn St. Louis Airport
Staff, cleanliness, nice clean room, location!
Reviewed on 3 Feb 2026
Drury Plaza Hotel St. Louis at the Arch
Yes… never was in a hotel where complimentary dinner included.
Reviewed on 5 Feb 2026
Other neighbourhoods around Downtown Clayton
Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Ladue
Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and St. Louis Art Museum are some interesting sights nearby to check out.
Dogtown
When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area.
The Hill
While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
