Photo by Najib Tecle
Downtown Clayton Hotels, St. Louis
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Our top choices for Downtown Clayton hotels
8.8 out of 10, Excellent, (3044)
"Clean room, good breakfast and good location "
Martin
The price is AU$170
includes taxes & fees
30 Dec - 31 Dec
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
Hannah
The price is AU$209
includes taxes & fees
1 Jan - 2 Jan 2026
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Seven Gables, St. Louis West, a Tribute Portfolio HotelDowntown Clayton
8.4 out of 10, Very good, (577)
"Love this place."
Robert
The price is AU$242
includes taxes & fees
1 Jan - 2 Jan 2026
9.0 out of 10, Wonderful, (228)
"The room was very clean and well designed.very quiet and restful. We were even given adjoining rooms without asking "
Elizabeth
The price is AU$226
includes taxes & fees
4 Jan - 5 Jan 2026
9.2 out of 10, Wonderful, (554)
"The stay was ok even though nothing was explained to be. The hours of restaurant, where the gym is located about the bar in the room nothing. "
Shemelle
The price is AU$867
includes taxes & fees
29 Dec - 30 Dec
9.4 out of 10, Exceptional, (2764)
"Great place to stay before your early morning flight. "
Henry
The price is AU$158
includes taxes & fees
1 Jan - 2 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Downtown Clayton
Find the best Downtown Clayton areas for the activities you enjoy most.
Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.
Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
St. Charles Historic District
St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.
Creve Coeur
Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.
Top Downtown Clayton Hotel Reviews
Drury Plaza Hotel St. Louis at the Arch
10/10 Excellent
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