Photo by Southernmost Illinois Tourism Bureau

Apartments in Southern Illinois

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
19 Dec - 21 Dec
In two weeks
26 Dec - 28 Dec
In one month
9 Jan - 11 Jan
In two months
6 Feb - 8 Feb

Our top choices for Southern Illinois apartments

1 bedroom, iron/ironing board, free WiFi, bed sheets
Unique loft in historic downtown

Unique loft in historic downtown

Unique loft in historic downtown
Vandalia
10.0 out of 10, Exceptional, (23)
"Clean, quaint, and conveniently located. Perfect for a weekend retreat!"
United States
Curtis T.
The price is AU$209
includes taxes & fees
15 Dec - 16 Dec
Unique loft in historic downtown
Fridge, microwave, oven, stovetop
30 West · The Den ·Downtown Hideaway near Fairground

30 West · The Den ·Downtown Hideaway near Fairground

30 West · The Den ·Downtown Hideaway near Fairground
Du Quoin
9.8 out of 10, Exceptional, (21)
"Super easy check in. The place was clean and comfortable. Really enjoyed the stay. Make sure you try St Nicholas Brewing, just down the street!"
United States
Shane W.
The price is AU$210
includes taxes & fees
13 Dec - 14 Dec
30 West · The Den ·Downtown Hideaway near Fairground
1 bedroom, WiFi, bed sheets
Justice- Book 1, 2 or 3 Cabins. Pet Friendly for a fee. Lake View

Justice- Book 1, 2 or 3 Cabins. Pet Friendly for a fee. Lake View

Justice- Book 1, 2 or 3 Cabins. Pet Friendly for a fee. Lake View
Goreville
10.0 out of 10, Exceptional, (7)
"Beautiful cabin , it had everything you needed. The host was very nice and helpful. The lake area is beautiful."
United States
Elizabeth
The price is AU$265
includes taxes & fees
14 Dec - 15 Dec
Justice- Book 1, 2 or 3 Cabins. Pet Friendly for a fee. Lake View
Private kitchen
Charming 2-bedroom apartment with AC, WiFi in tranquil Benton

Charming 2-bedroom apartment with AC, WiFi in tranquil Benton

Charming 2-bedroom apartment with AC, WiFi in tranquil Benton
Benton
10.0 out of 10, Exceptional, (8)
"Exceptionally clean & cozy! Had everything we needed & more! Would definitely stay here again!"
United States
Tiffany L.
The price is AU$203
includes taxes & fees
13 Dec - 14 Dec
Charming 2-bedroom apartment with AC, WiFi in tranquil Benton
2 bedrooms, iron/ironing board, WiFi, bed sheets
Charming 2-bedroom apartment with WiFi, AC in Pleasant Lawrenceville

Charming 2-bedroom apartment with WiFi, AC in Pleasant Lawrenceville

Charming 2-bedroom apartment with WiFi, AC in Pleasant Lawrenceville
2.0 star property
Lawrenceville
9.8 out of 10, Exceptional, (9)
"Great stay."
United States
Gerald B.
The price is AU$378
includes taxes & fees
13 Dec - 14 Dec
Charming 2-bedroom apartment with WiFi, AC in Pleasant Lawrenceville
2 bedrooms
The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.
Murphysboro
9.4 out of 10, Exceptional, (19)
"We were in town for a wedding, and this was the perfect place to stay. The Vrbo was well-stocked with everything you may need and very clean."
United States
Sean G.
The price is AU$311
includes taxes & fees
14 Dec - 15 Dec
The Lab! Come stay in our brand new space.
Interior
Cozy, and private apartment near Lake Shelbyville

Cozy, and private apartment near Lake Shelbyville

Cozy, and private apartment near Lake Shelbyville
Shelbyville
9.6 out of 10, Exceptional, (19)
"Very cool property!!!"
United States
Bernice K.
Cozy, and private apartment near Lake Shelbyville
Exterior
Copperfield- Unit 2 - 1 Bedroom Luxury Suite - King

Copperfield- Unit 2 - 1 Bedroom Luxury Suite - King

Copperfield- Unit 2 - 1 Bedroom Luxury Suite - King
Centralia
10.0 out of 10, Exceptional, (3)
"Excellent apartment in beautifully restored historic house. "
United States
James
The price is AU$280
includes taxes & fees
14 Dec - 15 Dec
Copperfield- Unit 2 - 1 Bedroom Luxury Suite - King
TV, fireplace
XCHNG Cozy Downtown Studio, XCHNG Studio

XCHNG Cozy Downtown Studio, XCHNG Studio

XCHNG Cozy Downtown Studio, XCHNG Studio
Effingham
10.0 out of 10, Exceptional, (26)
"Clean well kept loft that was close to everything we wanted to do had a good time "
United States
Bob F.
The price is AU$269
includes taxes & fees
14 Dec - 15 Dec
XCHNG Cozy Downtown Studio, XCHNG Studio
1 bedroom, iron/ironing board, WiFi, bed sheets
Luxury 1BR/BA Loft in the Heart of Downtown Marshall

Luxury 1BR/BA Loft in the Heart of Downtown Marshall

Luxury 1BR/BA Loft in the Heart of Downtown Marshall
Marshall
9.8 out of 10, Exceptional, (7)
"Gorgeous loft apartment! Beautifully decorated and great use of the space! Highly recommend! "
United States
Kristen
The price is AU$273
includes taxes & fees
14 Dec - 15 Dec
Luxury 1BR/BA Loft in the Heart of Downtown Marshall
Fridge, microwave, coffee/tea maker, toaster
Cozy 1-bedroom with AC and WiFi in charming Shelbyville

Cozy 1-bedroom with AC and WiFi in charming Shelbyville

Cozy 1-bedroom with AC and WiFi in charming Shelbyville
Shelbyville
8.8 out of 10, Excellent, (6)
"First time on this side. Wonderful stay. Close to everything. The bed is so comfy. "
United States
JR E.
Cozy 1-bedroom with AC and WiFi in charming Shelbyville
Interior
Cozy Loft Hideaway in Robinson

Cozy Loft Hideaway in Robinson

Cozy Loft Hideaway in Robinson
Robinson
10.0 out of 10, Exceptional, (3)
"Very pleasant stay. The loft was very clean and cozy as advertised."
United States
Mitchell M.
The price is AU$277
includes taxes & fees
20 Dec - 21 Dec
Cozy Loft Hideaway in Robinson
Fridge, microwave, oven, stovetop
Cozy 2BR Loft in Downtown Charleston, IL

Cozy 2BR Loft in Downtown Charleston, IL

Cozy 2BR Loft in Downtown Charleston, IL
Charleston
10.0 out of 10, Exceptional, (8)
"Cute little loft and great location in the main square with lots of walkable restaurants."
United States
Thomas
The price is AU$297
includes taxes & fees
16 Dec - 17 Dec
Cozy 2BR Loft in Downtown Charleston, IL
Dining
XCHNG Downtown Loft Living

XCHNG Downtown Loft Living

XCHNG Downtown Loft Living
2.0 star property
Effingham
10.0 out of 10, Exceptional, (3)
"Very convenient location, Very cosy and stylish apartment, with a big variety of things to do (f.e. games, the arcade machines were great!). But also nice shops and restaurants in walking distance to explore, very quiet at night."
Germany
slatomir w.
The price is AU$316
includes taxes & fees
14 Dec - 15 Dec
XCHNG Downtown Loft Living
TV, fireplace
XCHNG Corner Luxury Loft, XCHNG. Modern Loft in the heart of Effingham.

XCHNG Corner Luxury Loft, XCHNG. Modern Loft in the heart of Effingham.

XCHNG Corner Luxury Loft, XCHNG. Modern Loft in the heart of Effingham.
Effingham
10.0 out of 10, Exceptional, (16)
"We stayed here to attend a conference in Effingham, great location and the owners were very responsive and easy to work with."
United States
Cole F.
The price is AU$473
includes taxes & fees
14 Dec - 15 Dec
XCHNG Corner Luxury Loft, XCHNG. Modern Loft in the heart of Effingham.
Interior
Charming 1-bedroom apartment in historic Palestine in peaceful neighborhood

Charming 1-bedroom apartment in historic Palestine in peaceful neighborhood

Charming 1-bedroom apartment in historic Palestine in peaceful neighborhood
Palestine
The price is AU$181
includes taxes & fees
31 Dec - 1 Jan 2026
Charming 1-bedroom apartment in historic Palestine in peaceful neighborhood
Fridge, microwave, oven, stovetop
Studio with Queen Bed

Studio with Queen Bed

Studio with Queen Bed
Robinson
The price is AU$212
includes taxes & fees
13 Dec - 14 Dec
Studio with Queen Bed
Interior
Modern Queen Suite Near SIU Carbondale

Modern Queen Suite Near SIU Carbondale

Modern Queen Suite Near SIU Carbondale
Carbondale
9.6 out of 10, Exceptional, (14)
"Excellent stay"
United States
Aaron
Modern Queen Suite Near SIU Carbondale
Interior
Charming 2-bedroom apartment in beautiful Belleville with WiFi

Charming 2-bedroom apartment in beautiful Belleville with WiFi

Charming 2-bedroom apartment in beautiful Belleville with WiFi
Belleville
9.2 out of 10, Wonderful, (5)
"Great convenient location right outside st.Louis. THe house was very clean and comfortable!"
United States
Bobby C.
The price is AU$280
includes taxes & fees
14 Dec - 15 Dec
Charming 2-bedroom apartment in beautiful Belleville with WiFi
TV
The Loft at 116

The Loft at 116

The Loft at 116
2.0 star property
Olney
10.0 out of 10, Exceptional, (2)
"Good location, friendly town, clean, nicely decorated loved the balcony."
United States
Samuel R.
The price is AU$266
includes taxes & fees
31 Dec - 1 Jan 2026
The Loft at 116
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Best hotel stay we've had in a long time. "
Brenda 1-night trip
Posted 1 day ago
Drury Plaza Hotel Mt. Vernon

Find out more about Southern Illinois

Southern Illinois Apartments information

Number of reviews
192
Accommodation
103 Apartments
Lowest Price
AU$181
Highest Price
AU$473

Explore a world of travel with Expedia