Best Western Hotels in Southeast Ohio
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A forested area with a rocky overhang and a narrow path.

Best Western in Southeast Ohio from AU$117

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your current months are November, 2026 and December, 2026.

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Our top choices for Southeast Ohio Best Western

A modern bathroom with a flat-screen TV, a built-in microwave, a large bathtub, and a tiled floor.

A hotel room with a bed, two armchairs, a desk with a computer, a TV, a hot tub, and a wooden door.

A modern restaurant with a long counter, a coffee machine, and multiple tables and chairs.

1. Best Western Adena Inn

Best Western Adena Inn

2.5 star property

Chillicothe

7.8 out of 10, Good, (859 reviews)

7.8/10

Good

(859 reviews)

"We had to cancel our 2nd night due to an illness and we were able to be refunded. That was very much appreciated! The room was nice and clean I booked it for a very close friend from out of state to visit"

Tina

The price is AU$157

AU$157

includes taxes & fees

15 Nov - 16 Nov

Best Western Adena Inn

A hotel room with a large bed, a desk with a computer, a TV, a bathroom with a bathtub, and a patterned carpet.

A lobby with a seating area, a coffee station, and large windows with a view of the parking lot.

A lobby with a reception desk, seating area, and patterned carpet.

A brick building with a sign reading "Best Western" at night.

2. Best Western Canal Winchester Inn - Columbus South East

Best Western Canal Winchester Inn - Columbus South East

2.5 star property

Canal Winchester

7.8 out of 10, Good, (1,004 reviews)

7.8/10

Good

(1,004 reviews)

"I had an amazing front desk attendant so much so that on my return I plan to stay in the same hotel."

Paul

The price is AU$169

AU$169

includes taxes & fees

20 Nov - 21 Nov

Best Western Canal Winchester Inn - Columbus South East

A hotel lobby with a seating area, a TV mounted on the wall, a menu stand, and a dining area with tables and chairs.

A hotel entrance with a covered waiting area, stone pillars, and a clear view of the entrance doors.

A reception area with a wooden reception desk, a 'Welcome to OHI' sign, a small shelf with snacks, and a mirror on the wall.

An indoor swimming pool with clear water, surrounded by windows and seating areas.

3. Best Western St. Clairsville Inn & Suites

Best Western St. Clairsville Inn & Suites

2.5 star property

St. Clairsville

9.0 out of 10, Wonderful, (961 reviews)

9.0/10

Wonderful

(961 reviews)

"Very comfortable, quiet stay."

Lynn

The price is AU$118

AU$118

includes taxes & fees

15 Nov - 16 Nov

Best Western St. Clairsville Inn & Suites

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Best Western in Southeast Ohio from AU$117

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Southeast Ohio Best Western

1. Best Western Adena Inn

2. Best Western Canal Winchester Inn - Columbus South East

3. Best Western St. Clairsville Inn & Suites

Explore a world of travel with Expedia