A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

Historic Hotels & Resorts in Southeast Iowa from AU$225

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Iowa Historic Hotels

Tonight
23 Sept - 24 Sept
Tomorrow
24 Sept - 25 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Southeast Iowa historic hotels

A modern living room with a grey sofa, a glass coffee table, and a dining area with a table and chairs.
A modern kitchen with a microwave, oven, and refrigerator. There is a dining area with two black chairs and a table. The room has a wooden floor and a patterned rug.
A grassy area with a building, a pond, and trees.
A dining area with a wooden table and four black chairs with chrome bases. There are two pendant lights hanging above the table. The wall behind the table has a sign that reads "THE SHOP" and a framed picture.

1. "THE SHOP" retro 60's

"THE SHOP" retro 60's
Keosauqua
United States
Calicia
AU$231
includes taxes & fees
28 Sept - 29 Sept
"THE SHOP" retro 60's
A modern kitchen with stainless steel appliances, including a microwave, oven, and coffee maker.
A bathroom with a brick wall, a toilet, a trash can, and a small window.
A bedroom with a bed, a nightstand, a dresser, and an air conditioning unit.
A room with a grey wall, a sofa with floral upholstery, a black coffee table, and a painting of colorful trees.

2. Stay in Historic Downtown Keokuk

Stay in Historic Downtown Keokuk
Keokuk
United States
Roy
Stay in Historic Downtown Keokuk
A stacked washer and dryer unit in a corner of a room with beige walls and a wooden floor.
A bedroom with a large bed, a sofa, a desk with a lamp, and a painting on the wall.
A compact kitchen with a dishwasher, double sink, and wooden cabinets.
A living room with a beige sofa, a wooden chair, and a dining table.

3. The Red Front Suite - Sleeps 15

The Red Front Suite - Sleeps 15
Nauvoo
United States
Diane P.
AU$377
includes taxes & fees
28 Sept - 29 Sept
The Red Front Suite - Sleeps 15
A room with a wooden floor, a fireplace with a mantel, a door with glass panels, and a framed painting on the wall.
A living room with a sofa, armchairs, a patterned rug, and a stained glass window.
A kitchen with wooden cabinets, a white countertop, a dishwasher, and two rugs.
A grand staircase with ornate railings, a wooden table with a vase, and a patterned rug in a spacious room with wooden flooring and classic decor.

4. Grand Victorian on the Mississippi

Grand Victorian on the Mississippi
Fort Madison
United States
Theresa G.
AU$603
includes taxes & fees
19 Oct - 20 Oct
Grand Victorian on the Mississippi
A rustic brick interior with a fireplace, a wooden stool, and a checkered rug.
A rustic room with exposed brick walls, a wooden floor, a fireplace, a window with a curtain, and a wooden chair.
A staircase leading to a landing with a wooden chair and a decorative pillow.
A dining table with a tray of pinecones.

5. Experience Beautiful Pioneer Home In Nauvoo!

Experience Beautiful Pioneer Home In Nauvoo!
Nauvoo
United States
Darin B.
AU$521
includes taxes & fees
27 Sept - 28 Sept
Experience Beautiful Pioneer Home In Nauvoo!
A modern living room with a leather sofa, a wooden coffee table, and a blue armchair.
A modern building with a brick facade, large windows, and a fire hydrant in the foreground.
A modern kitchen with blue cabinets, a white island, and a brick wall.
A bedroom with a large bed, a dresser, a TV, and a window with blinds.

6. Idyllic Biggsville Vacation Rental: 10 Mi to River

Idyllic Biggsville Vacation Rental: 10 Mi to River
Biggsville
United States
Brennan
AU$314
includes taxes & fees
27 Sept - 28 Sept
Idyllic Biggsville Vacation Rental: 10 Mi to River
A modern living room with a leather sofa, a wooden coffee table, and a blue armchair.
A modern kitchen with blue cabinets, a white island, and a brick wall.
A spacious living area with a leather sofa, a blue armchair, and a dining area with a blue cabinet.
A building with a large garage door, a paved driveway, and a landscaped area with rocks and plants.

7. Idyllic Biggsville Vacation Rental: 10 Mi to River

Idyllic Biggsville Vacation Rental: 10 Mi to River
Biggsville
United States
Lisa S.
AU$324
includes taxes & fees
27 Sept - 28 Sept
Idyllic Biggsville Vacation Rental: 10 Mi to River
View all properties

Top Southeast Iowa Hotel Reviews

Super 8 by Wyndham Fort Madison

Super 8 by Wyndham Fort Madison

8/10 Good
"The facility and room were wonderful. The only negative was the so called breakfast. There was no protein, only instant oatmeal, packaged pancakes/waffles, yogurt, boiled eggs, milk and juice."
Russell 5-night trip
Posted 2 days ago
Super 8 by Wyndham Fort Madison
The Inn at Old Nauvoo

The Inn at Old Nauvoo

8/10 Good
"When I arrived, the staff said my Expedia account had put me in 3 different room for the 3 nights I was staying! Aarg!!!! That was as frustrating! It happened last time I stayed at this hotel and I assumed it was as them. No, EXPEDIA!! Please never do this to me again! Luckily, they noticed it and changed it!"
Marlynn 3-night trip
Posted 2 days ago
The Inn at Old Nauvoo
Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos

10/10 Excellent
"Very happy with our unit and the kindness shown by the office staff 😊"
Lori 2-night trip
Posted 2 days ago
Nauvoo Vacation Villas & Condos

Explore a world of travel with Expedia