Photo by Michael Schuier
Search Southeast Iowa hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southeast Iowa
Family friendly
Apartment
Check prices for these dates
Top hotels and accommodation in Southeast Iowa
The Catfish Bend Inn & Spa
Burlington
9.2 out of 10, Wonderful, (320)
"Staff was friendly and helpful. Accomodations were excellent."
Phillip
The price is AU$256
includes taxes & fees
6 Jan - 7 Jan 2026
Cobblestone Inn & Suites - Fort Madison
Fort Madison
9.4 out of 10, Exceptional, (646)
"Always love staying here while visiting family. Very clean and comfortable beds "
Jessica
The price is AU$126
includes taxes & fees
9 Dec - 10 Dec
Holiday Inn Express Hotel & Suites Burlington by IHG
Burlington
8.6 out of 10, Excellent, (463)
"Friendly staff and very clean hotel"
Julie
The price is AU$210
includes taxes & fees
4 Jan - 5 Jan 2026
Baymont by Wyndham Keokuk
Keokuk
6.2 out of 10, (488)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
Marty
The price is AU$90
includes taxes & fees
4 Jan - 5 Jan 2026
Super 8 by Wyndham Burlington
Burlington
6.0 out of 10, (756)
"Gal was very helpful and nice. Bed was comfortable, could use bigger pillows. There were several holes in the walls and the floor was dirty. "
Pam
The price is AU$92
includes taxes & fees
13 Dec - 14 Dec
Quality Inn & Suites
Mount Pleasant
7.8 out of 10, Good, (111)
"Very happy with my stay "
timothy
The price is AU$106
includes taxes & fees
4 Jan - 5 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southeast Iowa
Showing deals for:19 Dec - 21 Dec
Image gallery for Willard Richards Inn
Willard Richards Inn
Nauvoo
9.6/10Exceptional (160 reviews)
10% off
Price is AU$600
for 2 nights, 1 room
AU$300 per night
includes taxes & fees
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southeast Iowa attractions
Learn more about Southeast Iowa
Explore the family-friendly area of Southeast Iowa—a scenic riverfront, shopping and sights from Battle of Athens State Historic Site to Bentonsport National Historic District.
Photo by Michael Schuier
Open Photo by Michael Schuier
Top Southeast Iowa Hotel Reviews
Recent Reviews in Southeast Iowa
Baymont by Wyndham Keokuk
10/10 Excellent
More cheap accommodation in Southeast Iowa
Comfort Suites Burlington
1780 Stonegate Center Dr Burlington IA
The price is AU$186 per night from 28 Dec to 29 Dec
AU$186
28 Dec - 29 Dec
includes taxes & fees
8.6/10 Excellent! (738 reviews)
Explore a world of travel with Expedia
- Castles in Central United States
- Hostels in Central United States
- All Inclusive Hotels in Central United States
- Boutique Hotels in Central United States
- Family Hotels in Central United States
- Lgbt Welcoming Hotels in Central United States
- Luxury Hotels in Central United States
- Pet Friendly Hotels in Central United States
- Romantic Hotels in Central United States
- Ski Hotels in Central United States
- Central United States Hotels
- B&B in Historic Route 66
- Caravan Parks in Historic Route 66
- Guest Houses in Historic Route 66
- Cheap Hotels in Historic Route 66
- Luxury Hotels in Historic Route 66
- Historic Route 66 Hotels
- Inns in Historic Route 66
- Lodges in Historic Route 66
- Motels in Historic Route 66
- Resort in Historic Route 66
- Quad Cities Hotels
- Avis Rental Cars in Quad Cities
- Budget Rental Cars in Historic Route 66
- Car hire near Historic Route 66
- Car hire near Quad Cities
- Full-Size Car Hire in Historic Route 66
- Goldcar rental Rental Cars in Historic Route 66
- Luxury Car Hire in Historic Route 66
- Nü Car Rentals Rental Cars in Historic Route 66
- Nextcar Rental Cars in Central United States
- Routes Rental Cars in Historic Route 66
