Photo by Cindy Keese

Holiday Homes in Seneca

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Featured Holiday Homes in Seneca

Lake Keowee waterfront Escape!
10.0 out of 10, Exceptional, (15)
"This was my daughter wedding event, we can't be more happy about our stayed. we asked for an early checking and they were more than happy to help us. They are pet friendly, which is A+ for people like us that need to travel with ours fury babies. Great experience! we'll stay again next year."
Lake Keowee waterfront Escape!
Lake Hartwell - House w/dock, screened in porch and firepit
9.8 out of 10, Exceptional, (41)
"Perfect place for a peaceful relaxing vacation. We used the hot tub every day after being out on the lake fishing. We will definitely be back. "
Lake Hartwell - House w/dock, screened in porch and firepit
Home Game Weekender in Clemson - Spacious 5 Bed/4 Bath
2.0 star property
10.0 out of 10, Exceptional, (1)
"We were apprehensive as this was our first VRBO experience but this home was even better in person than the pictures conveyed! It had everything we needed to host our 2 sons and their girlfriends for a great football weekend. The neighborhood was extremely quiet except for the ice cream truck that came down the street Saturday afternoon ! We would definitely look to stay here again. "
Home Game Weekender in Clemson - Spacious 5 Bed/4 Bath
2-209C - Coopers Cozy Cabin ^ Lake Hartwell ^ WIFI ^ Pets Welcome
9.6 out of 10, Exceptional, (65)
"The house was very clean and comfortable. The view from the screened porch was beautiful & relaxing. Great location for renting a boat for use on Lake Hartwell. Great place!"
2-209C - Coopers Cozy Cabin ^ Lake Hartwell ^ WIFI ^ Pets Welcome
Gorgeous remodeled waterfront home for 12: pets welcome, covered deck, boat dock
9.6 out of 10, Exceptional, (29)
"Our family loved our time in your home. A few minor suggestions: Water pressure is low, we did not see a kayak (could be due to storm but it would have been helpful to know ), a cookie sheet would be helpful in the kitchen, and we did not have laundry detergent to start towels when we left this morning. Overall, excellent!! Just a few minor details. "
Gorgeous remodeled waterfront home for 12: pets welcome, covered deck, boat dock
Lake Keowee Escape w/ Dock, Deck & Lake Access!
9.4 out of 10, Exceptional, (120)
"We had a really good stay at the house."
Lake Keowee Escape w/ Dock, Deck & Lake Access!
The Brick House At Currahee
9.6 out of 10, Exceptional, (47)
"Our group had 3 adults and 4 kids and we were comfortable. There were plenty of space to sleep and lounge around. The back deck is also a lovely spot for morning tea or evening relaxation. The cottage is a short drive into town, Toccoa Falls, and nearby restaurants. It is obvious that the family host put a lot of love and care into the cottage. We especially appreciated the thoughtfulness of the host family offering to show their farm animals to our kids. Overall, it was a memorable experience!"
The price is AU$332
includes taxes & fees
18 Nov - 19 Nov
The Brick House At Currahee
Keowee Key Townhome #3 With a View of Golf Course plus Amenities
9.8 out of 10, Exceptional, (64)
"Very clean and welcoming!! Time to upgrade to a new mattress though. "
Keowee Key Townhome #3 With a View of Golf Course plus Amenities
EXCEPTIONAL, SUPER CLEAN! IN THE FOOTHILLS OF THE BLUE RIDGE MTN.! NO ANIMALS!
10.0 out of 10, Exceptional, (27)
"The place was very clean & very comfortable . Enjoyed the treats that were left for us. Lots of little extra things made the stay very pleasant ."
EXCEPTIONAL, SUPER CLEAN! IN THE FOOTHILLS OF THE BLUE RIDGE MTN.! NO ANIMALS!
CLEMSON Newly renovated- quick access to Patrick Square and Downtown, Stadium.
2.0 star property
10.0 out of 10, Exceptional, (2)
"This property is nestled in a quiet old neighborhood. Play corn hole in the tree lined back yard, or brush up on your knowledge of the 60s, 70s, 80s, and 90s with Trivial Pursuit, or watch the games on the enormous big screen in the reclining couch. The property is clean, has toiletries and towels waiting, and is a short drive to nearby Clemson area restaurants, campus, downtown, and Death Valley. The owners were easy to communicate with and didn’t ask much for check-out or charge a crazy...
CLEMSON Newly renovated- quick access to Patrick Square and Downtown, Stadium.
Valley Echoes on Lake Hartwell!
2.0 star property
Valley Echoes on Lake Hartwell!
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
9.8 out of 10, Exceptional, (331)
"Pictures on Vrbo did do this location justice. Enjoyed out stay"
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
10.0 out of 10, Exceptional, (212)
"Everything was perfect. Pictures and listing are very accurate. Lots of information was provided about the local area and things to do. Our hosts checked on us after check in to make sure all was good with the house. We highly recommend and look forward to returning when it’s a little warmer so we can go in the lake."
😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
10.0 out of 10, Exceptional, (53)
"Excellent property "
Beautiful 5 Acre Lakefront Private Retreat w/ Boat Dock, Hot Tub, 5 Bdrm/ 5 bath
Incredible 10 BR home with pool
8.0 out of 10, Very good, (1)
"Close to Seneca and Clemson University. Go Tigers!! This house is very spacious and well appointed for large groups of people. It is still early in the season so they were not quite ready for us. The pool, hot tub, wi-fi, televisions were not operational. There was no communicaiton sent to us about any of these none working items. Without notice, a tech was sent to the property (our first morning) to attempt to get the Wi-Fi up and running, however, the passwords are with the home owner...
Incredible 10 BR home with pool
Lakefront Cabin Retreat. Private Setting. Sleeps 20. Boat Rental.
10.0 out of 10, Exceptional, (37)
"We had a lot of fun at this house. Plenty of room to spread out or share spaces together with large groups. The view was beautiful with the sun glistening off the water. Their was plenty to do here with the Pickleball court, pool table, and kayaks."
Lakefront Cabin Retreat. Private Setting. Sleeps 20. Boat Rental.
Bunk/Game Room, Near Lake, Pet Friendly, Firepit, FUN!
9.8 out of 10, Exceptional, (34)
"We had booked our stay for vacation time for my husband and I, with family gathering later in the stay to celebrate 3 birthdays. Then Hurricane Milton started heading towards us and we decided to evacuate. Luckily, the cabin was available and our Host worked with us, making our evacuation a calm and pleasant stay. The cabin was decorated for Halloween/Fall and was comfortable for just the two of us and for the group of us. We made wonderful memories @ Camp Tugaloo celebrating 3 family...
Bunk/Game Room, Near Lake, Pet Friendly, Firepit, FUN!
Welcoming home with huge deck overlooking lake. Pet Friendly!
10.0 out of 10, Exceptional, (8)
"The property was fantastic! Very clean, spacious, felt like home! Travis made everything very easy from the booking to the checkout, we will be back! Thanks Travis for making this an enjoyable family get together! "
Welcoming home with huge deck overlooking lake. Pet Friendly!
Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson
10.0 out of 10, Exceptional, (193)
"I’ve stayed at several homes on Lake Keowee. This is my favorite stay so far. Beautiful home - right on the lake. I will definitely be returning. Loved it. "
Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson
Fall/Winter Specials! Big water views, private dock, pool table, 15 min Clemson!
10.0 out of 10, Exceptional, (35)
"Lovely"
Fall/Winter Specials! Big water views, private dock, pool table, 15 min Clemson!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Seneca

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
9.8 out of 10, Exceptional, (127)
"We had a lovely time! Steve was very responsive and alerted us early when they’d lost power during the hurricane. It all worked out in the end! Perfect distance from Clemson to have a reunion with alumni. "
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!
10.0 out of 10, Exceptional, (78)
"Pictures in the listing looked amazing but it’s hard to capture how awesome the home, views and location truly are. Cloudwalker was the perfect place for our family vacation and communication with the owner was seamless. We can’t wait to book this property again!"
The price is AU$2,412
includes taxes & fees
3 Nov - 4 Nov
5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub!
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
9.8 out of 10, Exceptional, (331)
"Pictures on Vrbo did do this location justice. Enjoyed out stay"
4/3 Waterfront Home w/ Covered Dock, 2 Decks, Pet Friendly. Long view on lake.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.