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Top hotels and accommodation in Seneca

Lakeside Lodge Clemson

2.5 star property
Seneca
9.0 out of 10, Wonderful, (1002)
"Rooms are spacious quiet and clean"
United States
Holly
Travelling for leisure
The price is AU$204
includes taxes & fees
8 Dec - 9 Dec
Lakeside Lodge Clemson

Quality Inn Seneca Clemson Area US-123

2.5 star property
Downtown
8.0 out of 10, Very good, (664)
"Great price, very convenient, good bed."
United States
Richard
The price is AU$131
includes taxes & fees
14 Dec - 15 Dec
Quality Inn Seneca Clemson Area US-123

Best Western Seneca-Clemson

2.5 star property
Seneca
8.4 out of 10, Very good, (639)
"Pillows and beds were very comfortable"
United States
Elizabeth
Travelling solo
The price is AU$148
includes taxes & fees
14 Dec - 15 Dec
Best Western Seneca-Clemson

Tru by Hilton Seneca Clemson

2.5 star property
Seneca
9.2 out of 10, Wonderful, (789)
"The property was nice and close to a lot of places to eat that are walking distance."
United States
LaKeisha
Travelling for business
The price is AU$158
includes taxes & fees
22 Dec - 23 Dec
Tru by Hilton Seneca Clemson

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
Seneca
9.8 out of 10, Exceptional, (49)
"The view of the woods out of the large window as you lay in bed is relaxing"
United States
julie
Travelling for leisure
The price is AU$214
includes taxes & fees
8 Dec - 9 Dec
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Safe area and easy parking"
United States
Nicole
Travelling for business
The price is AU$191
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites Seneca Clemson Univ Area

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
Seneca
9.2 out of 10, Wonderful, (661)
"Nice rooms Bed covers could be a little thicker Loved the pool"
United States
Carmen
Travelling with partner
The price is AU$171
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn & Suites Seneca-Clemson Area

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
Seneca
6.8 out of 10, (720)
"The rooms have been renovated it was nice and clean especially for the price."
United States
Sherri
The price is AU$111
includes taxes & fees
24 Dec - 25 Dec
Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Anderson

2.0 star property
Anderson
7.8 out of 10, Good, (1001)
"Room was spacious and clean."
United States
Hadiya
The price is AU$105
includes taxes & fees
10 Dec - 11 Dec
Days Inn by Wyndham Anderson

Hampton Inn Hartwell

2.5 star property
Hartwell
9.2 out of 10, Wonderful, (333)
"The room and lobby was very clean"
United States
Melanie
Travelling with small children
The price is AU$177
includes taxes & fees
19 Dec - 20 Dec
Hampton Inn Hartwell

Baymont by Wyndham Easley/Greenville

2.5 star property
Easley
7.4 out of 10, Good, (744)
"Great water pressure in the shower!"
United States
Sara
Travelling for leisure
The price is AU$125
includes taxes & fees
8 Dec - 9 Dec
Baymont by Wyndham Easley/Greenville

Rodeway Inn & Suites Walhalla

2.0 star property
Walhalla
7.6 out of 10, Good, (174)
"Comfortable, clean, convenient and well located near nature interests in the area."
United States
Cheryl
Travelling for leisure
The price is AU$114
includes taxes & fees
5 Jan - 6 Jan 2026
Rodeway Inn & Suites Walhalla

Holiday Inn Express Anderson by IHG

2.5 star property
Anderson
8.6 out of 10, Excellent, (383)
"The staff was very nice"
United States
Lori
The price is AU$176
includes taxes & fees
12 Dec - 13 Dec
Holiday Inn Express Anderson by IHG

Hampton Inn & Suites Lavonia

2.5 star property
Lavonia
9.0 out of 10, Wonderful, (375)
"Great staff very friendly breakfasts were delicious spacious room clean"
United States
miles
Travelling for leisure
The price is AU$188
includes taxes & fees
3 Jan - 4 Jan 2026
Hampton Inn & Suites Lavonia

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
Anderson
8.2 out of 10, Very good, (1002)
"Very clean and Got me right into my room!"
United States
Hannah
The price is AU$134
includes taxes & fees
14 Dec - 15 Dec
Microtel Inn & Suites by Wyndham Anderson/Clemson

Quality Inn Clemson near University

2.5 star property
Anderson
7.0 out of 10, Good, (889)
"The bed was simply wonderful Everything was clean & tidy."
United States
Allen
Travelling for leisure
The price is AU$78
includes taxes & fees
23 Dec - 24 Dec
Quality Inn Clemson near University

Hilton Garden Inn Anderson

3.0 star property
Anderson
9.0 out of 10, Wonderful, (674)
"Clean,everyone was very friendly,loved the pool."
United States
Katherine
Travelling for leisure
The price is AU$173
includes taxes & fees
13 Dec - 14 Dec
Hilton Garden Inn Anderson

Rodeway Inn

2.0 star property
Anderson
7.8 out of 10, Good, (316)
"Good size room and convenient"
United States
Rick
Travelling solo
The price is AU$100
includes taxes & fees
9 Dec - 10 Dec
Rodeway Inn

Carolina Camp Cedar

3.5 star property
Pickens
The price is AU$300
includes taxes & fees
8 Dec - 9 Dec
Carolina Camp Cedar

Clemson Memorabilia House

3.0 star property
Clemson
9.8 out of 10, Exceptional, (8)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is AU$348
includes taxes & fees
10 Dec - 11 Dec
Clemson Memorabilia House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Seneca, SC

Showing deals for:19 Dec - 21 Dec
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Our guide on where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most. Learn more about Seneca
Learn more about Seneca

Downtown

If you're spending some time in Downtown, Seneca Historic District and The Gauntlet are top sights worth seeing.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and World of Energy.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like The Gauntlet and Seneca Historic District.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Seneca Historic District and Keowee Reservoir are some notable places to visit nearby.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

Recent Reviews in Seneca

More cheap accommodation in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel offers free breakfast and free parking. Traveller reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
What are some of the best holiday rentals that Seneca has to offer?
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.: This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 6 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Seneca include 5🌟 Modern Lakefront Luxury Oasis 🇺🇸 270° Lake Views w/Dock & Hot Tub! and Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Quality Inn Seneca Clemson Area US-123 is a top hotel for people travelling with their pets, and offers a seasonal outdoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Lakeside Lodge Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Quality Inn Seneca Clemson Area US-123: Features daily, a seasonal outdoor pool and free self parking. Lakeside Lodge Clemson and Days Inn by Wyndham Seneca / Clemson Area are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 290 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Lake Keowee, Lake Hartwell and Keowee Reservoir. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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