Santa Fe de Antioquia Travel Guide

Tourist Guide

A historic fountain with water jets, surrounded by lush greenery and a white church with a bell tower in the background.
A street with buildings, a motorcycle, a tricycle, and a mountain in the background.
A vintage-themed living room with a large arched wall, a vintage camera, a red armchair, a wooden cabinet, and a large black and white portrait.
A colorful bus with 'La Santafrenia' written on it parked in front of a building with a tiled roof.
A white tuk-tuk parked on a cobblestone street in a historic town.

Our guide on where to stay in Santa Fe de Antioquia

Find the best Santa Fe de Antioquia areas for the activities you enjoy most.
A narrow street flanked by white buildings with green shutters, a clear sky, and mountains in the background.
Photo by Botak Jon
Open Photo by Botak Jon

Zona Colonial

While visiting Zona Colonial, you might make a stop by sights like Cathedral of Santa Fe de Antioquia and Bolivar Square.

Arde La Selva

Arde La Selva

4 out of 5
km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia
The price is AU$243 per night from 10 Sept to 11 Sept
AU$243
10 Sept - 11 Sept
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Museo Juan del Corral and Bolivar Square ...
Arde La Selva
Ivanna Hotel Campestre - Santa Fe de Antioquia

Ivanna Hotel Campestre - Santa Fe de Antioquia

4.5 out of 5
Via Anza Vereda, KM 1, Obregon Santa Fe de Antioquia Antioquia
The price is AU$98 per night from 15 Sept to 16 Sept
AU$98
15 Sept - 16 Sept
Stay at this luxury hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and 2 outdoor pools. Popular attractions Bolivar Square and Cathedral of ...
7.6/10 Good! (9 reviews)
"Amazing staff, Swimming pool and spa Hot tub Wonderful area secluded Relaxing atmosphere with all the amenities"

Reviewed on 30 Aug 2026

Ivanna Hotel Campestre - Santa Fe de Antioquia
Hotel Boutique Al Alma

Hotel Boutique Al Alma

4.5 out of 5
#9-50 Cra. 8 Santa Fe de Antioquia Antioquia
The price is AU$279 per night from 20 Sept to 21 Sept
AU$279
20 Sept - 21 Sept
Stay at this luxury hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free beach cabanas. Popular attractions Bolivar Square and Cathedral ...
9.4/10 Exceptional! (64 reviews)
"Great place! Staff was awsone. We had a wonderful time."

Reviewed on 10 Aug 2026

Hotel Boutique Al Alma
See all 482 properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Finca hotel mi refugio

Finca hotel mi refugio

2 out of 5
1541 Camino real Santa Fé de Antioquia Antioquia
Stay at this cottage in Santa Fe de Antioquia. Enjoy free Wi-Fi, free parking and a garden. Popular attractions Bolivar Square and Cathedral of Santa Fe de Antioquia ...
Finca hotel mi refugio
SANTA FE DE ANTIOQUIA

SANTA FE DE ANTIOQUIA

2 out of 5
111 Cl. 8 Santa Fe de Antioquia Antioquia
Stay at this aparthotel in Santa Fe de Antioquia. Enjoy free Wi-Fi, 6 outdoor pools and a garden. Popular attractions Bolivar Square and Cathedral of Santa Fe ...
8/10 Very good! (1 review)
"Todo Ok"

Reviewed on 10 Feb 2025

SANTA FE DE ANTIOQUIA
Otalu Suites

Otalu Suites

3 out of 5
Diagonal 80A #45E 09 Medellín Antioquia
Stay at this apartment in Medellín. Enjoy free Wi-Fi, a fitness centre and a 24-hour front desk. Popular attractions Atanasio Giradot Stadium and Botero Plaza ...
Otalu Suites
See all properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Fe de Antioquia attractions

Cathedral of Santa Fe de Antioquia

9.0/10 (28 reviews)
You can learn about the history of Santa Fe de Antioquia when you stop by Cathedral of Santa Fe de Antioquia. Make time to visit the monuments and cathedral while you're in the area.
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Activities

Horseback Riding Tour and Coffee Tour with Lunch and Refreshment

Horseback Riding Tour and Coffee Tour with Lunch and Refreshment

AU$128
per adult
Horseback Riding Tour and Coffee Tour with Lunch and Refreshment
Tour Santa Fe de Antioquia

Tour Santa Fe de Antioquia

AU$209
per adult
Tour Santa Fe de Antioquia
Coffee tour in Medellín with tastings and transportation

Coffee tour in Medellín with tastings and transportation

AU$105
per adult
100% of travellers recommend
Coffee tour in Medellín with tastings and transportation
Cloud Forest and Highlands Private 4X4 Day Trip From Medellin

Cloud Forest and Highlands Private 4X4 Day Trip From Medellin

AU$314
per traveller
Cloud Forest and Highlands Private 4X4 Day Trip From Medellin
Private Coffee & Panel Tour Near Medellin All Inclusive

Private Coffee & Panel Tour Near Medellin All Inclusive

AU$209
per adult
Private Coffee & Panel Tour Near Medellin All Inclusive
Tour Santa Fe De Antioquia

Tour Santa Fe De Antioquia

AU$342
per traveller
Tour Santa Fe De Antioquia
See all activities in Santa Fe de Antioquia