Search Santa Fe hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 May - 13 May
Tomorrow
13 May - 14 May
This weekend
15 May - 17 May
Next weekend
22 May - 24 May

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Fe hotels

Free daily full breakfast

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
Starke
9.6 out of 10, Exceptional, (549 reviews)
"Facility was very clean and breakfast was very good. Would definitely stay again. "
United States
Sheila
The price is AU$187
includes taxes & fees
11 June - 12 June
Holiday Inn Express Starke by IHG
Outdoor pool

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
Waldo
8.8 out of 10, Excellent, (999 reviews)
"The breakfast area was clean. Enjoyed the wide selection of food."
United States
Jeanne
The price is AU$158
includes taxes & fees
19 May - 20 May
Best Western Waldo Inn and Suites
Lobby

Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,347 reviews)
"Very nice and clean, good breakfast"
United States
Natalya
The price is AU$146
includes taxes & fees
24 May - 25 May
Comfort Suites Gainesville near University
Exterior

La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
3.0 star property
Gainesville
9.0 out of 10, Wonderful, (1,223 reviews)
"The hotel was clean, complementary breakfast was better than most, bed was comfortable, and the room was spacious. We would definitely stay here again."
United States
MICHELLE
The price is AU$145
includes taxes & fees
13 May - 14 May
La Quinta by Wyndham Gainesville
Exterior

Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1,817 reviews)
"We had the best stay here. Will stay here the next time we are in town! "
United States
Elisabeth
The price is AU$143
includes taxes & fees
2 June - 3 June
Country Inn & Suites by Radisson, Gainesville, FL
Standard Double Room

Soho Inn Waldo

Soho Inn Waldo
2.0 star property
Waldo
5.2 out of 10, (20 reviews)
"Clean linens and towels, lots of parking, room is newly painted. There’s TV, A/C, microwave. Receptionist is very nice. "
Canada
Cynthia
The price is AU$109
includes taxes & fees
13 May - 14 May
Soho Inn Waldo
Exterior

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
2.0 star property
Gainesville
7.6 out of 10, Good, (1,018 reviews)
"Clean room, welcoming staff, location great"
United States
Jon
The price is AU$84
includes taxes & fees
17 May - 18 May
Super 8 by Wyndham Gainesville I-75 Hospital University Area
Lobby

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,474 reviews)
"Everything about our stay was perfect. The staff is friendly and I loved the breakfast. "
United States
Gregory
The price is AU$163
includes taxes & fees
26 May - 27 May
Drury Inn & Suites Gainesville
Exterior

Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,206 reviews)
"We had a great stay! Breakfast was good and the staff were very nice. "
United States
Christina
The price is AU$134
includes taxes & fees
9 June - 10 June
Sleep Inn & Suites University/Shands
Premium bedding, desk, blackout curtains, soundproofing

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (606 reviews)
"Staff nice and helpful"
United States
Drew
The price is AU$101
includes taxes & fees
13 May - 14 May
Palms Garden Inn
Exterior

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,013 reviews)
"Great stay, nice area"
United States
Jennifer
The price is AU$158
includes taxes & fees
24 May - 25 May
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Reception

Best Western Gateway Grand

Best Western Gateway Grand
3.0 star property
Gainesville
8.6 out of 10, Excellent, (1,472 reviews)
"The staff was very helpful with checking and out and shuttle to the airport"
United States
Alesa
The price is AU$144
includes taxes & fees
19 May - 20 May
Best Western Gateway Grand
Breakfast area

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (510 reviews)
"Room was very clean, breakfast was awesome, everything was good."
United States
James
The price is AU$144
includes taxes & fees
31 May - 1 June
Hampton Inn & Suites Alachua I-75
Exterior

Hampton Inn Gainesville

Hampton Inn Gainesville
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,008 reviews)
"Love this hotel and the staff. "
United States
Tamara
The price is AU$146
includes taxes & fees
24 May - 25 May
Hampton Inn Gainesville
Exterior

Comfort Inn University

Comfort Inn University
2.5 star property
Gainesville
8.4 out of 10, Very good, (1,061 reviews)
"Clean and staff was amazing the breakfast was perfect"
United States
Christina
The price is AU$134
includes taxes & fees
26 May - 27 May
Comfort Inn University
Lobby sitting area

HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
2.5 star property
Gainesville
8.6 out of 10, Excellent, (1,927 reviews)
"Clean rooms, good breakfast would stay here again "
United States
Seana
The price is AU$133
includes taxes & fees
17 May - 18 May
HOM Hotel Gainesville, SureStay Collection by Best Western
Lobby

SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1,007 reviews)
"Hotel was great, friendly staff. "
United States
AnaMaria
The price is AU$144
includes taxes & fees
24 May - 25 May
SpringHill Suites by Marriott Gainesville
Meeting facility

Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
3.5 star property
Gainesville
8.4 out of 10, Very good, (1,017 reviews)
"A very good stay at a clean hotel."
United States
Kenneth
The price is AU$177
includes taxes & fees
26 May - 27 May
Hilton University of Florida Conference Center Gainesville
Lobby

Fairfield Inn & Suites by Marriott Gainesville I-75

Fairfield Inn & Suites by Marriott Gainesville I-75
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,008 reviews)
"Very clean and staff was very friendly. "
United States
Lorty
The price is AU$185
includes taxes & fees
17 May - 18 May
Fairfield Inn & Suites by Marriott Gainesville I-75
Free daily full breakfast

Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
2.5 star property
Alachua
7.2 out of 10, Good, (1,015 reviews)
"Solid hotel for the price"
United States
Michael
The price is AU$115
includes taxes & fees
8 June - 9 June
Quality Inn Alachua - Gainesville Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Fe Hotel Reviews

Recent Reviews in Santa Fe

Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

10/10 Excellent
"Yes Everything was excellent! There was a complete breakfast for us and we were satisfied completely!"
Elaine 3-night trip
Posted 1 hour ago
Country Inn & Suites by Radisson, Gainesville, FL

More cheap accommodation in Santa Fe

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL
The price is AU$100 per night from 8 June to 9 June
AU$100
8 June - 9 June
includes taxes & fees
7.4/10 Good! (1,298 reviews)

Frequently asked questions

What's the best place for a stay in Santa Fe?
Located 18.6 mi (29.9 km) from the heart of Santa Fe, Country Inn & Suites by Radisson, Gainesville, FL is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Sleep Inn & Suites University/Shands and Drury Inn & Suites Gainesville. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best holiday rentals that Santa Fe has to offer?
Family-Friendly Gainesville Home - Walk to UF - Pool + Sleeps 16: This holiday home rental outside of Santa Fe offers an outdoor pool, a fireplace and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. It offers a balcony, a garden and a selection of games so that you can immerse yourself in your holiday. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
What is staying in Santa Fe like?
Travellers to Santa Fe will find plenty to explore and enjoy. There are 781 hotels and other accommodation options in the surrounding area. Find out more about Santa Fe.
What is there to see in Santa Fe?
Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park and Camp Kulaqua Conservation Easement. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Take a look at what more there is to see and do in Expedia's Santa Fe guide.
What's the weather like in Santa Fe?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 15°C. The rainiest months in Santa Fe are August, June, July and September, with each month seeing an average of 177 mm of rainfall.

Explore a world of travel with Expedia