Guadalupe District Travel Guide

Tourist Guide

A great evening visiting the art galleries topped with a stop at a brew pub draft in the Santa Fe Railroad Artisan Museum district.
A great evening visiting the art galleries topped with a stop at a brew pub draft in the Santa Fe Railroad Artisan Museum district.
The church with a moonlit backdrop. #GoldenHour
The Santa Fe Railyard is social place in the center of town where you can grab a bite to eat, access bike and walking trails, and on the weekends explore a great farmer's market. #newmexico #santafe
This is a purely residential area with nothing to offer but great people and amazing Old Santa Fe architecture.  It's one of those "only locals know" streets.  

#CeliaLuzPhotography #BW #architecture #SantaFe #NewMexico #statue #streetart #local #travel #angel

Popular places to visit

Activities


Our pick of the best Guadalupe District Hotel Deals

Guadalupe Inn

Guadalupe Inn

2 out of 5
604 Agua Fria St. Santa Fe NM
The price is AU$152 per night from 10 Feb to 11 Feb
AU$152
10 Feb - 11 Feb
includes taxes & fees
Stay at this hotel in Santa Fe. Enjoy free Wi-Fi, parking (surcharge) and a business centre. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (999 reviews)
So well located, such hospitality, and such a good price, how could it be so? It was. Thank you for a comfortable room, breakfast and your welcome.

Reviewed on 2 Feb 2026

Guadalupe Inn
Perfect downtown location in historic district- 9.5 walk score! Historic home.

Perfect downtown location in historic district- 9.5 walk score! Historic home.

Santa Fe NM
Stay at this family-friendly holiday home in Santa Fe. Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Santa Fe Plaza and Santa Fe River ...
9.8/10 Exceptional! (105 reviews)
We just loved this place! Totally authentic. Totally centric, yet on a totally quiet residential block. Super comfortable, great kitchen, cozy working fireplace. Outdoor space in front for dining al fresco and in back for BBQ/relaxing. Host is awesome. This is now our new go-to spot in Santa Fe!

Reviewed on 17 Jan 2026

Perfect downtown location in historic district- 9.5 walk score! Historic home.
La Fonda on the Plaza

La Fonda on the Plaza

4 out of 5
100 E San Francisco St Santa Fe NM
The price is AU$368 per night from 8 Mar to 9 Mar
AU$368
8 Mar - 9 Mar
includes taxes & fees
Stay at this historic hotel in Santa Fe. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in their ...
9.2/10 Wonderful! (1,099 reviews)
Yea it was all clean and good. Thx

Reviewed on 6 Feb 2026

La Fonda on the Plaza
The Sage Hotel

The Sage Hotel

3 out of 5
725 Cerrillos Rd Santa Fe NM
The price is AU$113 per night from 10 Feb to 11 Feb
AU$113
10 Feb - 11 Feb
includes taxes & fees
Stay at this business-friendly hotel in Santa Fe. Enjoy an outdoor pool, room service and a 24-hour fitness centre. Our guests praise the breakfast and the restaurant ...
7.8/10 Good! (2,207 reviews)
Clean room, pictures not as they appear

Reviewed on 3 Feb 2026

The Sage Hotel
Inn and Spa at Loretto

Inn and Spa at Loretto

4 out of 5
211 Old Santa Fe Trail Santa Fe NM
The price is AU$381 per night from 22 Feb to 23 Feb
AU$381
22 Feb - 23 Feb
includes taxes & fees
Stay at this business-friendly hotel in Santa Fe. Enjoy breakfast (surcharge), a fitness centre and on-site spa services. Our guests praise the restaurant and ...
9/10 Wonderful! (1,003 reviews)
Amazing hotel with tge most delicious restaurant and the best service!!

Reviewed on 6 Feb 2026

Inn and Spa at Loretto
Drury Plaza Hotel in Santa Fe

Drury Plaza Hotel in Santa Fe

3.5 out of 5
828 Paseo de Peralta Santa Fe NM
The price is AU$230 per night from 16 Feb to 17 Feb
AU$230
16 Feb - 17 Feb
includes taxes & fees
Stay at this business-friendly hotel in Santa Fe. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (1,446 reviews)
Clean and friendly Great location Good breakfast and happy hour

Reviewed on 29 Jan 2026

Drury Plaza Hotel in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Guadalupe District

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West Manhattan

West Manhattan might not have many top sights, but Santa Fe Railyard and Santuario De Nuestra Senora de Guadalupe are two attractions nearby that you can check out.

West Manhattan
A great evening visiting the art galleries topped with a stop at a brew pub draft in the Santa Fe Railroad Artisan Museum district.

Railyard Arts District

Art galleries, shopping and spas highlight some of the noteworthy features of Railyard Arts District. Make a stop by Santa Fe Railyard or Santa Fe Farmers Market while you're exploring the neighbourhood.

Railyard Arts District
New Mexico Museum of Art which includes a statue or sculpture and art

Downtown Santa Fe

5/5(5 area reviews)

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops and acclaimed art galleries. You might also want to make some time to see Santuario De Nuestra Senora de Guadalupe or Lensic Performing Arts Center while you're exploring the neighbourhood.

Downtown Santa Fe
Delicious vegan and vegetarian options for breakfast and lunch. I had the vegan skillet with green chili and cucumber water
#santafe #eats #summer #weekendgetaway

West Guadaloupe

While West Guadaloupe may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Harrell House of Natural Oddities and Bug Museum and Santuario De Nuestra Senora de Guadalupe.

West Guadaloupe
My favorite juice/smoothie/breakfast place in Santa Fe.  They also sell general goods and offer lunch.  
#places #eat #generalgoods #store #goods #flowers #coffee #restaurants #santafe #travel #breakfast #lunch #smoothies #juices #healthy

Don Diego

If you're spending some time in Don Diego, Santa Fe Climbing Gym and Santa Fe Symphony Orchestra and Chorus are top sights worth seeing.

Don Diego
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Casa Solana

When in Casa Solana, you can plan a visit to Harrell House of Natural Oddities and Bug Museum and Santuario De Nuestra Senora de Guadalupe, some noteworthy sights in the nearby area.

Casa Solana


Guadalupe District Travel Guide

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