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Our top choices for Santa Cruz Mixtepec hotels

LA PATRONA HOSTAL

LA PATRONA HOSTAL
2.0 star property
Santa Cruz Xoxocotlán
10.0 out of 10, Exceptional, (1)
The price is AU$33
includes taxes & fees
2 Jan - 3 Jan 2026
LA PATRONA HOSTAL

Maria Ines Hotel Suite

Maria Ines Hotel Suite
3.5 star property
San Agustín de las Juntas
9.4 out of 10, Exceptional, (392)
"Great service and friendly staff. Clean room close to the airport."
United States
Jeffrey
Maria Ines Hotel Suite

Motel Puerta del Cielo

Motel Puerta del Cielo
2.5 star property
San Agustín de las Juntas
8.6 out of 10, Excellent, (4)
"Good "
United States
Manuel
The price is AU$129
includes taxes & fees
2 Jan - 3 Jan 2026
Motel Puerta del Cielo

Hotel Guivá Aeropuerto

Hotel Guivá Aeropuerto
3.0 star property
San Agustín de las Juntas
7.4 out of 10, Good, (32)
"Staff was friendly and helpful. Check on and out was easy and quick. Room was clean. "
United States
fernando
The price is AU$143
includes taxes & fees
25 Dec - 26 Dec
Hotel Guivá Aeropuerto

Hotel boutique Casa Gopar

Hotel boutique Casa Gopar
3.0 star property
Ocotlán de Morelos
The price is AU$73
includes taxes & fees
21 Jan - 22 Jan 2026
Hotel boutique Casa Gopar

Villas Horizonte Oaxaca

Villas Horizonte Oaxaca
3.0 star property
Santa María Coyotepec
6.8 out of 10, (3)
"Rooms are nice and clean, they gave me a room without air conditioned but I told them I booked a room with AC and they gave me another room. The hotel is out of downtown, no noise, streets are not paved in that area. It is a good chooce If you don’t want to expend too much money. "
United States
Lourdes
The price is AU$76
includes taxes & fees
1 Jan - 2 Jan 2026
Villas Horizonte Oaxaca

OYO Hotel Rey David, Oaxaca

OYO Hotel Rey David, Oaxaca
2.5 star property
Ocotlán de Morelos
4.4 out of 10, (32)
"No AC, Fans, Poor Place"
United States
Javier
The price is AU$38
includes taxes & fees
4 Jan - 5 Jan 2026
OYO Hotel Rey David, Oaxaca

Motel Las Maravillas

Motel Las Maravillas
2.0 star property
Santa Cruz Xoxocotlán
3.0 out of 10, (4)
"Dirty rooms, broken washrooms, terrible linen and towels. "
Canada
Rajan
The price is AU$154
includes taxes & fees
3 Jan - 4 Jan 2026
Motel Las Maravillas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Santa Cruz Mixtepec?
Maria Ines Hotel Suite, located 19.6 mi (31.5 km) from the heart of Santa Cruz Mixtepec, is a top choice for your stay, based on our traveller data. Two other choices for your trip to the area are OYO Hotel Rey David, Oaxaca and Motel Puerta del Cielo. See all available top hotels, or vacation rentals in Santa Cruz Mixtepec.
What are some of the best holiday rentals that Santa Cruz Mixtepec has to offer?
Casa MaryFer: This holiday home rental outside Santa Cruz Mixtepec offers a terrace, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, an oven and a microwave. See all vacation rentals in Santa Cruz Mixtepec.
If I need to cancel my hotel reservation in Santa Cruz Mixtepec, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz Mixtepec.
What's it like to stay in Santa Cruz Mixtepec?
Visitors will definitely enjoy all that Santa Cruz Mixtepec has to offer. There are 34 hotels and other accommodation options in the surrounding area. Find out more about Santa Cruz Mixtepec.
What are the top places to visit in Santa Cruz Mixtepec?
Places to visit in the wider area include Dona Rosa Studio, Convento de Cuilapam and Workshop of Jacobo and Maria Angeles. Take a look at what more there is to see and do in Expedia's Santa Cruz Mixtepec guide.
What's the weather like in Santa Cruz Mixtepec?
The hottest months are usually April and May, with an average temperature of 19°C, while the coldest months are January and December, with an average of 16°C. The rainiest months in Santa Cruz Mixtepec are September, June, August and July, with each month seeing an average of 237 mm of rainfall.

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