Luxury Hotels & Resorts in Santa Cruz from AU$55

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Best Santa Cruz Luxury Hotels

UTOPIC Polanco by ULIV

4.5 star property
Miguel Hidalgo
9.0 out of 10, Wonderful, (718)
"We had a great stay. Area was safe to walk around, and hotel was near tourist attractions. "
United States
Guadalupe
UTOPIC Polanco by ULIV

Fiesta Americana México Satélite

4.5 star property
Tlalnepantla de Baz
9.4 out of 10, Exceptional, (740)
"nice hotel and great location "
United States
karen
The price is AU$164
includes taxes & fees
16 Dec - 17 Dec
Fiesta Americana México Satélite

Hyatt Regency Mexico City

5.0 star property
Polanco
9.4 out of 10, Exceptional, (1323)
"Beautiful location hotel staff "
United States
Rajat
The price is AU$423
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency Mexico City

Kukun Inspire Polanco

4.0 star property
Polanco
9.4 out of 10, Exceptional, (202)
"Loved the view from the balcony and very friendly staff. "
United States
Claudia
The price is AU$222
includes taxes & fees
23 Dec - 24 Dec
Kukun Inspire Polanco

UTOPIC Campos Elíseos by ULIV

4.0 star property
Polanco
9.4 out of 10, Exceptional, (633)
"Great location! Lovely hotel and property. The staff were very professional and friendly. "
United States
Alecia
UTOPIC Campos Elíseos by ULIV

Capitalia Aristoteles Polanco

4.0 star property
Polanco
9.2 out of 10, Wonderful, (110)
"Great location and a nice apartment "
United States
Luis F
The price is AU$303
includes taxes & fees
4 Jan - 5 Jan 2026
Capitalia Aristoteles Polanco

Capitalia Antara Polanco

4.5 star property
Polanco
9.2 out of 10, Wonderful, (164)
"Super smooth. Great rooms!!"
United States
Javier
Capitalia Antara Polanco

Orchid House Mexico City

4.5 star property
Polanco
9.2 out of 10, Wonderful, (409)
"Courteous staff, clean rooms, perfect location"
United States
Diana
Orchid House Mexico City

The Wild Oscar

4.0 star property
Polanco
9.6 out of 10, Exceptional, (481)
"Don't delay - book the Wild Óscar "
United States
Kasha
The Wild Oscar

InterContinental Presidente Mexico City by IHG

4.0 star property
Polanco
9.4 out of 10, Exceptional, (2080)
"Great location and the staff was super friendly."
United States
Felipe
The price is AU$470
includes taxes & fees
3 Jan - 4 Jan 2026
InterContinental Presidente Mexico City by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Santa Cruz

Santa Cruzand its attractions for luxury travelers

Santa Cruz in Tepotzotlán, State of Mexico, offers a luxurious retreat for discerning travellers. Begin your adventure at the stunning Ex Convento de San Francisco Javier, a UNESCO World Heritage site, where you can marvel at Baroque architecture and intricate frescoes that transport you to a bygone era. For those seeking a dash of nature, the nearby Parque Nacional de Tepotzotlán provides picturesque hiking trails, perfect for family outings or serene walks amidst lush greenery. Don't miss the enchanting Museo del Virreinato, showcasing historic art and history, which offers an immersive glimpse into the region's past. After a day of exploration, unwind at a luxurious hotel situated in the heart of the historic centre, where attentive service meets modern amenities, ensuring a pampered stay. Indulge in exquisite dining experiences at your hotel, featuring local gourmet cuisine, and relish in the convenience of being steps away from vibrant markets and artisan shops, making your stay both comfortable and culturally enriching.

Top Santa Cruz Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Santa Cruz holiday?
Expedia can help you arrange a flight to Santa Lucía, Mexico (NLU-Felipe Ángeles Intl.) airport or Benito Juarez International Airport (MEX) airport, and then you can select from various places to stay that will deliver the luxury you'd like to find. Amenities are important when you plan a holiday, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel that has a spa, an indoor pool or luxury bedding, Expedia can help you find the best luxury hotel experience that Santa Cruz offers.
When can I expect good weather in Santa Cruz?
Planning for the weather is an important factor for making your trip to Santa Cruz a success, especially when you're splurging. The hottest months are usually April and May, with an average temperature of 18°C, while the coldest months are January and December, with an average of 14°C. The rainiest months in Santa Cruz are August, July, September and June, with each month seeing an average of 186 mm of rainfall.
What's there to see and do in Santa Cruz?
Enjoy all that Santa Cruz has to offer when you visit Hacienda La Concepcion, National Museum of the Viceroyalty and San Marcos Power Center. If you have a little extra time during your trip, you might want to make a stop at Xochitla Ecological Park and Arcos del Sitio.

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