Search Santa Cruz hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Hotel Finca Las Hortensias

Hotel Finca Las Hortensias
3.0 star property
Tepotzotlán
8.4 out of 10, Very good, (189 reviews)
"Nice rooms and grounds."
United States
Raymond
The price is AU$98
includes taxes & fees
16 Apr - 17 Apr
Hotel Finca Las Hortensias

La Morada Tepotzotlan Boutique & Spa

La Morada Tepotzotlan Boutique & Spa
3.5 star property
Tepotzotlán
7.8 out of 10, Good, (42 reviews)
"na"
Mexico
Karina Ponce
The price is AU$406
includes taxes & fees
22 Apr - 23 Apr
La Morada Tepotzotlan Boutique & Spa

Hotel Único La Villa

Hotel Único La Villa
2.0 star property
Gustavo A. Madero
7.0 out of 10, Good, (43 reviews)
"If you are looking for a place to sleep, it does the job (quarters are tight and there aren't any perks). The room appears to be recently remodeled. "
United States
Martha
The price is AU$73
includes taxes & fees
15 Apr - 16 Apr
Hotel Único La Villa

Hotel El Aguila

Hotel El Aguila
3.0 star property
Villa del Carbón
9.0 out of 10, Wonderful, (46 reviews)
"Great stay "
United States
Bill
The price is AU$74
includes taxes & fees
4 May - 5 May
Hotel El Aguila

Antigua Hotel Boutique

Antigua Hotel Boutique
3.5 star property
Ciudad López Mateos
9.4 out of 10, Exceptional, (125 reviews)
"Great location and service."
United States
Jorge Gabriel
The price is AU$114
includes taxes & fees
19 Apr - 20 Apr
Antigua Hotel Boutique

Verticca Hotel

Verticca Hotel
3.0 star property
Ojo de Agua
9.2 out of 10, Wonderful, (278 reviews)
"Everything was great we like the place."
United States
Gilberto
The price is AU$252
includes taxes & fees
15 Apr - 16 Apr
Verticca Hotel

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
3.5 star property
Zumpango
9.4 out of 10, Exceptional, (1,115 reviews)
"Very clean hotel and friendly staff."
United States
Pedro
The price is AU$225
includes taxes & fees
11 May - 12 May
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Fiesta Inn Ecatepec

Fiesta Inn Ecatepec
3.5 star property
Ecatepec de Morelos
8.8 out of 10, Excellent, (924 reviews)
"Room was great service and clean and great staff"
United States
LUIS
The price is AU$160
includes taxes & fees
24 Apr - 25 Apr
Fiesta Inn Ecatepec

City Express by Marriott Tepotzotlan

City Express by Marriott Tepotzotlan
3.5 star property
Tepotzotlán
8.6 out of 10, Excellent, (763 reviews)
"Just few yards before the Tepotzotlan toll booth. Great for overnight stay "
United States
VICTOR
The price is AU$110
includes taxes & fees
1 May - 2 May
City Express by Marriott Tepotzotlan

Hotel Brasilia

Hotel Brasilia
3.0 star property
Gustavo A. Madero
9.0 out of 10, Wonderful, (1,008 reviews)
"The room was very clean and spacious, and the staff was very friendly. I would stay there again."
United States
guillermo guerrero
The price is AU$101
includes taxes & fees
29 Apr - 30 Apr
Hotel Brasilia

HOTEL CASA KAVIA

HOTEL CASA KAVIA
2.0 star property
Miguel Hidalgo
9.6 out of 10, Exceptional, (72 reviews)
"Everything very nice"
United States
Marcela
The price is AU$224
includes taxes & fees
16 Apr - 17 Apr
HOTEL CASA KAVIA

One Ciudad de Mexico La Raza

One Ciudad de Mexico La Raza
3.0 star property
Cuauhtémoc
8.6 out of 10, Excellent, (1,002 reviews)
"The staff is excellent, the room clean and comfortable. Breakfast was good. "
United States
Gabriela
The price is AU$99
includes taxes & fees
15 May - 16 May
One Ciudad de Mexico La Raza

Fairfield Inn & Suites Mexico City Vallejo

Fairfield Inn & Suites Mexico City Vallejo
3.0 star property
Azcapotzalco
9.2 out of 10, Wonderful, (1,006 reviews)
"Great amenities and walking distance to a mall"
United States
REY ANTHONY
The price is AU$147
includes taxes & fees
1 May - 2 May
Fairfield Inn & Suites Mexico City Vallejo

Hotel Villas Natura

Hotel Villas Natura
3.0 star property
Cuautitlan Izcalli
8.4 out of 10, Very good, (142 reviews)
"Place is just fine, no major complaints. Very reasonable pricing."
United States
Ivan
The price is AU$68
includes taxes & fees
16 Apr - 17 Apr
Hotel Villas Natura

Ramada by Wyndham CDMX Perinorte

Ramada by Wyndham CDMX Perinorte
3.5 star property
Tlalnepantla de Baz
8.4 out of 10, Very good, (374 reviews)
"Great service and friendly staff"
United States
Ricardo
The price is AU$95
includes taxes & fees
21 Apr - 22 Apr
Ramada by Wyndham CDMX Perinorte

Moderna, Cómoda Suite Nube en Tepotzotlán centro

Moderna, Cómoda Suite Nube en Tepotzotlán centro
4.0 star property
Tepotzotlán
9.8 out of 10, Exceptional, (6 reviews)
"El lugar es maravilloso"
Mexico
Karen Lizeth
The price is AU$95
includes taxes & fees
16 Apr - 17 Apr
Moderna, Cómoda Suite Nube en Tepotzotlán centro

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG
3.0 star property
Cuauhtémoc
9.2 out of 10, Wonderful, (1,105 reviews)
"Clean room , staff, breakfast, parking all things are excellent. We enjoyed your hospitality, thank you "
United States
Shanti
The price is AU$124
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express Mexico Basilica by IHG

KALI La Raza Mexico City

KALI La Raza Mexico City
2.5 star property
Cuauhtémoc
9.2 out of 10, Wonderful, (301 reviews)
"Clean rooms, staff is really friendly. I highly recommend. "
United States
Abigail
The price is AU$95
includes taxes & fees
16 Apr - 17 Apr
KALI La Raza Mexico City

KALI Vallejo Mexico City

KALI Vallejo Mexico City
3.0 star property
Azcapotzalco
8.8 out of 10, Excellent, (349 reviews)
"Clean hotel, friendly staff."
United States
ana
The price is AU$71
includes taxes & fees
19 Apr - 20 Apr
KALI Vallejo Mexico City

Gran Hotel Panorama

Gran Hotel Panorama
3.0 star property
Cuauhtémoc
8.4 out of 10, Very good, (1,000 reviews)
"Friendly staff very clean and perfect for the price recommended….."
Canada
Allen
The price is AU$40
includes taxes & fees
16 Apr - 17 Apr
Gran Hotel Panorama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Recent Reviews in Santa Cruz

More cheap accommodation in Santa Cruz

Frequently asked questions

Where is the best place for a stay in Santa Cruz?
Located 18.9 mi (30.4 km) from the heart of Santa Cruz, InterContinental Presidente Mexico City by IHG is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Hyatt Regency Mexico City and Downtown Treasure Place. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Polanco Stay: Outdoor Space & Explore Nearby: This holiday home rental outside of Santa Cruz offers a garden, a selection of games and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is staying in Santa Cruz like?
Those travelling to Santa Cruz will definitely enjoy the sights to see and things to do. In Santa Cruz, there are 2 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What are the top places to visit in Santa Cruz?
Places to visit in the wider area include Hacienda La Concepcion, San Marcos Power Center and Xochitla Ecological Park. You'll also find Arcos del Sitio and Premium Outlet Punta Norte in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather like in Santa Cruz?
The hottest months are usually April and May, with an average temperature of 18°C, while the coldest months are January and December, with an average of 14°C. The rainiest months in Santa Cruz are August, July, September and June, with each month seeing an average of 186 mm of rainfall.

Explore a world of travel with Expedia