
Medical Center District Hotels, San Antonio
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
Tomorrow
This weekend
Next weekend
Our top choices for Medical Center District hotels

1. San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical CenterMedical Center District
8.6 out of 10, Excellent, (1,075 reviews)
The price is AU$171
includes taxes & fees
12 June - 13 June

2. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NWMedical Center District
8.4 out of 10, Very good, (3,412 reviews)
The price is AU$149
includes taxes & fees
9 June - 10 June

3. Flex Studios
Flex StudiosMedical Center District
6.0 out of 10, (541 reviews)
The price is AU$66
includes taxes & fees
9 June - 10 June

4. OYO Inn & Suites Medical Center San Antonio
OYO Inn & Suites Medical Center San AntonioMedical Center District
7.4 out of 10, Good, (238 reviews)
The price is AU$101
includes taxes & fees
26 June - 27 June

5. Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical CenterMedical Center District
9.2 out of 10, Wonderful, (1,346 reviews)
The price is AU$151
includes taxes & fees
21 June - 22 June

6. Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San AntonioMedical Center District
8.8 out of 10, Excellent, (1,004 reviews)
The price is AU$149
includes taxes & fees
26 June - 27 June

7. Motel 6 San Antonio, TX - Northwest Medical Center
Motel 6 San Antonio, TX - Northwest Medical CenterMedical Center District
6.0 out of 10, (1,001 reviews)
The price is AU$83
includes taxes & fees
9 June - 10 June

8. Park Inn by Radisson
Park Inn by RadissonMedical Center District
7.2 out of 10, Good, (1,000 reviews)
The price is AU$110
includes taxes & fees
10 June - 11 June

9. Fairfield Inn & Suites by Marriott San Antonio Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical CenterMedical Center District
9.0 out of 10, Wonderful, (1,009 reviews)
The price is AU$142
includes taxes & fees
21 June - 22 June

10. Studio 6 Extended Stay - San Antonio, TX - Medical Center
Studio 6 Extended Stay - San Antonio, TX - Medical CenterMedical Center District
6.8 out of 10, (910 reviews)
The price is AU$87
includes taxes & fees
9 June - 10 June

11. Studio 6 San Antonio, Tx - Northwest Medical Center
Studio 6 San Antonio, Tx - Northwest Medical CenterMedical Center District
7.4 out of 10, Good, (300 reviews)
The price is AU$78
includes taxes & fees
1 July - 2 July

12. Atria Inn & Suites
Atria Inn & SuitesMedical Center District
7.4 out of 10, Good, (296 reviews)
The price is AU$94
includes taxes & fees
9 June - 10 June

13. Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Country Inn & Suites by Radisson, San Antonio Medical Center, TXMedical Center District
7.0 out of 10, Good, (1,003 reviews)
The price is AU$97
includes taxes & fees
29 June - 30 June

14. Plaza San Antonio Hotel & Spa, Autograph Collection
Plaza San Antonio Hotel & Spa, Autograph CollectionDowntown San Antonio, 12.9 km from Medical Center District
9.4 out of 10, Exceptional, (838 reviews)
The price is AU$257
includes taxes & fees
5 July - 6 July

15. Tru by Hilton San Antonio North
Tru by Hilton San Antonio North20 km from Medical Center District
8.8 out of 10, Excellent, (724 reviews)
The price is AU$118
includes taxes & fees
29 June - 30 June

16. Spark by Hilton San Antonio Dominion
Spark by Hilton San Antonio Dominion19.5 km from Medical Center District
9.0 out of 10, Wonderful, (429 reviews)
The price is AU$99
includes taxes & fees
22 June - 23 June

17. Extended Stay America Premier Suites - San Antonio - Schertz
Extended Stay America Premier Suites - San Antonio - Schertz29.4 km from Medical Center District
9.2 out of 10, Wonderful, (301 reviews)
The price is AU$162
includes taxes & fees
9 June - 10 June

18. Hampton Inn & Suites Schertz
Hampton Inn & Suites Schertz31.1 km from Medical Center District
8.8 out of 10, Excellent, (904 reviews)
The price is AU$131
includes taxes & fees
30 June - 1 July

19. The Maverick, powered by Placemakr - River Walk
The Maverick, powered by Placemakr - River WalkDowntown San Antonio, 12.3 km from Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
The price is AU$212
includes taxes & fees
21 June - 22 June

20. Best Western Garden Inn
Best Western Garden InnUptown, 21.2 km from Medical Center District
8.2 out of 10, Very good, (1,000 reviews)
The price is AU$113
includes taxes & fees
9 June - 10 June
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Medical Center District
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Drury Inn & Suites San Antonio Northwest Medical Center | 9.2 Wonderful 1,346 reviews | View | ||||||
![]() Fairfield Inn & Suites by Marriott San Antonio Medical Center | 9.0 Wonderful 1,009 reviews | View | ||||||
![]() Courtyard by Marriott Medical Center San Antonio | 8.8 Excellent 1,004 reviews | View | ||||||
![]() San Antonio Marriott Northwest Medical Center | 8.6 Excellent 1,075 reviews | View | ||||||
![]() La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW | 8.4 Very good 3,412 reviews | View |
Our guide on where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Alamo Quarry Market are top sights worth seeing.

Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Ridge Market and Shops at Hardy Oak while you're in town.

La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Frequently asked questions
Explore a world of travel with Expedia
- Alamo Heights Hotels
- Hotels near Alamo
- Alamo Plaza Hotels
- Hotels near Alamo Quarry Market
- Beacon Hill Hotels
- Hotels near Buckhorn Saloon and Museum
- Cheap Hotels in Castle Hills
- Castle Hills Hotels
- Hotels near Charline McCombs Empire Theatre
- Downtown San Antonio Hotels
- Hotels near La Villita
- Leon Valley Hotels
- Family Hotels in Mahncke Park
- Midtown Hotels
- North San Antonio - SAT Hotels
- Hotels near North Star Mall
- Cheap Hotels in Northwest San Antonio
- Northwest San Antonio Hotels
- Cheap Hotels in Parkwood
- Prospect Hill Hotels
- Hotels near River Walk
- San Antonio Hotels
- Hotels near San Antonio Intl.
- Hotels near San Antonio River
- Hotels near Shops at Rivercenter
- Hotels near Six Flags Fiesta Texas
- Hotels near The Rim Shopping Center
- Hotels near The Shops of La Cantera
- Family Hotels in Tobin Hill
- Hotels near Travis Park
- Hotels near University of Texas at San Antonio
- Hotels near University of Texas Health and Science Center at San Antonio
- Vance Jackson Hotels
- Golf Hotels in West San Antonio
- West San Antonio Hotels
- Cheap Hotels in Woodridge
- Woodridge Hotels
- Flights to North San Antonio - SAT
- Flights to San Antonio Intl.
- Flights to San Antonio
- Flights from El Paso to West San Antonio
- Flights from Dallas to North San Antonio - SAT
- Flights from Dallas to West San Antonio
- Flights from Denver to West San Antonio
- Flights from Phoenix to West San Antonio
- Flights from Portland to West San Antonio
- Flights from Adelaide (ADL) to San Antonio (SAT)
- Flights from Austin (AUS) to San Antonio (SAT)
- Flights from Nashville (BNA) to San Antonio (SAT)
- Flights from Brisbane (BNE) to San Antonio (SAT)
- Flights from Mumbai (BOM) to San Antonio (SAT)
- Flights from Burbank (BUR) to San Antonio (SAT)
- Flights from Canberra (CBR) to San Antonio (SAT)
- Flights from Condobolin (CBX) to San Antonio (SAT)
- Flights from Chicago (CHI) to San Antonio (SAT)
- Flights from Cancun (CUN) to San Antonio (SAT)
- Flights from Clovis (CVN) to San Antonio (SAT)
- Flights from Dallas (DFW) to San Antonio (SAT)
- Flights from Newark Liberty Intl. Airport (EWR) to San Antonio (SAT)
- Flights from Flagstaff (FLG) to San Antonio (SAT)
- Flights from Hong Kong (HKG) to San Antonio (SAT)
- Flights from Honolulu (HNL) to San Antonio (SAT)
- Flights from Houston (IAH) to San Antonio (SAT)
- Flights from New York (JFK) to San Antonio (SAT)
- Flights from Las Vegas (LAS) to San Antonio (SAT)
- Flights from Los Angeles (LAX) to San Antonio (SAT)
- Flights from Orlando (MCO) to San Antonio (SAT)
- Flights from Melbourne (MEL) to San Antonio (SAT)
- Flights from Manila (MNL) to San Antonio (SAT)
- Flights from New Orleans (MSY) to San Antonio (SAT)
- Flights from Naples (NAP) to San Antonio (SAT)
- Flights from Gold Coast (OOL) to San Antonio (SAT)
- Flights from Perth (PER) to San Antonio (SAT)
- Flights from Port Macquarie (PQQ) to San Antonio (SAT)
- Flights from San Francisco (SFO) to San Antonio (SAT)
- Flights from Sikeston (SIK) to San Antonio (SAT)
- Flights from Singapore (SIN) to San Antonio (SAT)
- Flights from Orange County (SNA) to San Antonio (SAT)
- Flights from Malabo (SSG) to San Antonio (SAT)
- Flights from Newburgh (SWF) to San Antonio (SAT)
- Flights from Sale (SXE) to San Antonio (SAT)
- Flights from Sydney (SYD) to San Antonio (SAT)
- Flights from Sandefjord (TRF) to San Antonio (SAT)
- Flights from Drayton Valley (YDC) to San Antonio (SAT)
- Flights from Vancouver (YVR) to San Antonio (SAT)
- Flights from Toronto (YYZ) to San Antonio (SAT)
- Car hire near Blessed Sacrament Catholic Church
- Car hire near Country
- Car hire near Northwest San Antonio
- Rental cars San Antonio Intl. airport
- Car hire near San Antonio
- Car hire in Dollar Rent A Car Calle De Diaz Del Castillo, 7
- Guerin Rental Cars in West San Antonio
- Rent A Wreck Rental Cars in San Antonio Intl.




























































































