Medical Center District Hotels, San Antonio

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Our top choices for Medical Center District hotels

1. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,075 reviews)
"The hotel’s location is great. The reception staff was welcoming and friendly, and the rooms are always clean. "
United States
Maria
The price is AU$171
includes taxes & fees
12 June - 13 June
San Antonio Marriott Northwest Medical Center

2. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,412 reviews)
"Great stay"
United States
Marques
The price is AU$149
includes taxes & fees
9 June - 10 June
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3. Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (541 reviews)
"Yes I would stay again"
United States
Jasper
The price is AU$66
includes taxes & fees
9 June - 10 June
Flex Studios

4. OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.4 out of 10, Good, (238 reviews)
"It was quiet and clean and the staff was very friendly"
United States
Ronnie
The price is AU$101
includes taxes & fees
26 June - 27 June
OYO Inn & Suites Medical Center San Antonio

5. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,345 reviews)
"Great breakfast and safe parking."
United States
Josue
The price is AU$151
includes taxes & fees
21 June - 22 June
Drury Inn & Suites San Antonio Northwest Medical Center

6. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,003 reviews)
"Great value and staff was very kind!"
United States
Zane Contreras
The price is AU$149
includes taxes & fees
26 June - 27 June
Courtyard by Marriott Medical Center San Antonio

7. Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,001 reviews)
"Everyone In that hotels Is pretty friendly and great service."
United States
José
The price is AU$83
includes taxes & fees
9 June - 10 June
Motel 6 San Antonio, TX - Northwest Medical Center

8. Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,000 reviews)
"Is a good place with good parking and service costumer"
United States
Raymond
The price is AU$110
includes taxes & fees
9 June - 10 June
Park Inn by Radisson

9. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,009 reviews)
"Was a great stay. "
United States
Sunanda
The price is AU$142
includes taxes & fees
21 June - 22 June
Fairfield Inn & Suites by Marriott San Antonio Medical Center

10. Studio 6 Extended Stay - San Antonio, TX - Medical Center

Studio 6 Extended Stay - San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (909 reviews)
"It was an amazing stay "
United States
Cordale
The price is AU$87
includes taxes & fees
9 June - 10 June
Studio 6 Extended Stay - San Antonio, TX - Medical Center

11. Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (300 reviews)
"We liked that the property was quiet and staff was courteous and helpful. We would have liked more towels in the bathroom."
United States
Alma
The price is AU$78
includes taxes & fees
1 July - 2 July
Studio 6 San Antonio, Tx - Northwest Medical Center

12. Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (296 reviews)
"The stay wasn’t HORRIBLE but it definitely wasn’t great. When we got to our room there were old clothes from previous guest in the drawers…on top of that we needed clean towels and they had nothing available. The worst part to say though is that there were some very suspicious people walking around and peeping through my truck window-I’m not sure if they were even guests. I thought the neighborhood was good but it’s actually kinda bad, so don’t expect a relaxing night. Everything else was mid...
United States
Alyssa
The price is AU$94
includes taxes & fees
9 June - 10 June
Atria Inn & Suites

13. Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
7.0 out of 10, Good, (1,003 reviews)
"It was a comfortable stay"
United States
Eric
The price is AU$97
includes taxes & fees
29 June - 30 June
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

14. Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection
4.0 star property
Downtown San Antonio, 12.9 km from Medical Center District
9.4 out of 10, Exceptional, (838 reviews)
"Love staying here!"
United States
Bryanda
The price is AU$257
includes taxes & fees
5 July - 6 July
Plaza San Antonio Hotel & Spa, Autograph Collection

15. Tru by Hilton San Antonio North

Tru by Hilton San Antonio North
2.5 star property
20 km from Medical Center District
8.8 out of 10, Excellent, (724 reviews)
"Great place to stay in"
United States
Yuelin
The price is AU$118
includes taxes & fees
29 June - 30 June
Tru by Hilton San Antonio North

16. Spark by Hilton San Antonio Dominion

Spark by Hilton San Antonio Dominion
3.0 star property
19.5 km from Medical Center District
9.0 out of 10, Wonderful, (429 reviews)
"Clean hotel and friendly staff! I would stay there again. "
United States
Jacob
The price is AU$116
includes taxes & fees
22 June - 23 June
Spark by Hilton San Antonio Dominion

17. Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
29.4 km from Medical Center District
9.2 out of 10, Wonderful, (301 reviews)
"The place was awesome and will definitely stay again"
United States
Joshua
The price is AU$162
includes taxes & fees
9 June - 10 June
Extended Stay America Premier Suites - San Antonio - Schertz

18. Hampton Inn & Suites Schertz

Hampton Inn & Suites Schertz
2.5 star property
31.1 km from Medical Center District
8.8 out of 10, Excellent, (904 reviews)
"Excellent stay! "
United States
Roxanne
The price is AU$132
includes taxes & fees
7 July - 8 July
Hampton Inn & Suites Schertz

19. The Maverick, powered by Placemakr - River Walk

The Maverick, powered by Placemakr - River Walk
4.0 star property
Downtown San Antonio, 12.3 km from Medical Center District
8.8 out of 10, Excellent, (1,001 reviews)
"Great service awesome clean rooms great location everything is absolutely amazing"
United States
Jacob
The price is AU$212
includes taxes & fees
21 June - 22 June
The Maverick, powered by Placemakr - River Walk

20. Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown, 21.2 km from Medical Center District
8.2 out of 10, Very good, (1,000 reviews)
"Very clean, really enjoyed our stay in this place"
United States
Frederick Magtibay
The price is AU$113
includes taxes & fees
9 June - 10 June
Best Western Garden Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Medical Center District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,345 reviews
View
Lobby
Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
9.0
Wonderful
1,009 reviews
View
Bar (on property)
Courtyard by Marriott Medical Center San Antonio
3.0 star property
8.8
Excellent
1,003 reviews
View
Lobby
San Antonio Marriott Northwest Medical Center
3.5 star property
8.6
Excellent
1,075 reviews
View
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
8.4
Very good
3,412 reviews
View

Our guide on where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Alamo Quarry Market are top sights worth seeing.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Ridge Market and Shops at Hardy Oak while you're in town.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on our traveller data, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW is one of the top choices for your stay in Medical Center District. This hotel offers free breakfast and an outdoor pool. Other good options for your stay in the area include San Antonio Marriott Northwest Medical Center and Drury Inn & Suites San Antonio Northwest Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 135 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

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