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Our top choices for Prairie Home hotels

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn
2.5 star property
Columbia
8.8 out of 10, Excellent, (1206)
"room was very clean and properly filled with amenities and bathing supplies"
United States
Rebecca
Travelling for business
The price is AU$117
includes taxes & fees
2 Jan - 3 Jan 2026
Best Western Plus Columbia Inn

Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1724)
"Room was very clean as was the rest of the hotel."
United States
Erin
Travelling for leisure
The price is AU$132
includes taxes & fees
22 Jan - 23 Jan 2026
Country Inn & Suites by Radisson, Columbia, MO

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1212)
"The hotel was very clean, and offered a good variety for breakfast."
United States
Sherri
Travelling with friends
The price is AU$137
includes taxes & fees
5 Jan - 6 Jan 2026
Wingate by Wyndham - Columbia

Ramada by Wyndham Columbia

Ramada by Wyndham Columbia
2.5 star property
Columbia
7.6 out of 10, Good, (1006)
"Very clean and easy access to any room."
United States
jose
The price is AU$110
includes taxes & fees
31 Dec - 1 Jan 2026
Ramada by Wyndham Columbia

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East
3.0 star property
Columbia
9.6 out of 10, Exceptional, (1349)
"Excellent accommodations and our room was perfect!"
United States
Willie
Travelling for leisure
The price is AU$165
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Plaza Hotel Columbia East

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
2.5 star property
Columbia
8.8 out of 10, Excellent, (1000)
"Room in excellent condition, hotel easily accessible from highway."
United States
Alan
The price is AU$168
includes taxes & fees
18 Jan - 19 Jan 2026
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Wyndham Executive Center Columbia

Wyndham Executive Center Columbia
3.5 star property
Columbia
8.4 out of 10, Very good, (1006)
"room was clean and perfect for our 2-night stay with lots of room"
United States
Julie
Travelling for business
The price is AU$143
includes taxes & fees
25 Jan - 26 Jan 2026
Wyndham Executive Center Columbia

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO
2.5 star property
Columbia
8.2 out of 10, Very good, (636)
"I loved that the bathroom light switch glowed at night."
United States
Pamela
Travelling for leisure
The price is AU$99
includes taxes & fees
5 Jan - 6 Jan 2026
Baymont by Wyndham Columbia, MO

Fairfield Inn & Suites by Marriott Columbia

Fairfield Inn & Suites by Marriott Columbia
2.5 star property
Columbia
8.2 out of 10, Very good, (580)
"Safe area and great breakfast"
United States
Caroline
The price is AU$158
includes taxes & fees
3 Jan - 4 Jan 2026
Fairfield Inn & Suites by Marriott Columbia

Holiday Inn Columbia East by IHG

Holiday Inn Columbia East by IHG
3.0 star property
Columbia
8.4 out of 10, Very good, (1003)
"We really enjoyed our stay, it [stay] was conveniently located near all the places i needed to go."
United States
Amber
Travelling for leisure
The price is AU$190
includes taxes & fees
15 Jan - 16 Jan 2026
Holiday Inn Columbia East by IHG

Hampton Inn Columbia

Hampton Inn Columbia
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1001)
"the hotel was very quiet and clean"
United States
Loren
Travelling with family
The price is AU$120
includes taxes & fees
16 Jan - 17 Jan 2026
Hampton Inn Columbia

Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70
2.5 star property
Columbia
7.0 out of 10, Good, (808)
"The bed was comfortable, slept well."
United States
Toni
The price is AU$89
includes taxes & fees
2 Jan - 3 Jan 2026
Quality Inn & Suites Columbia I-70

Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia
2.5 star property
Columbia
8.6 out of 10, Excellent, (1364)
"Clean room, nice staff, and great pool and hot tub area"
United States
jackie
Travelling with family
Stoney Creek Hotel Columbia

Super 8 by Wyndham Columbia East

Super 8 by Wyndham Columbia East
2.0 star property
Columbia
6.4 out of 10, (1000)
"But the shower and tub worked fine, the room size was good, and it was a quiet stay."
United States
Jodi
Travelling with small children
The price is AU$91
includes taxes & fees
7 Jan - 8 Jan 2026
Super 8 by Wyndham Columbia East

Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard
3.0 star property
Columbia
9.4 out of 10, Exceptional, (1003)
"Incredibly friendly staff and clean room."
United States
Lisa
The price is AU$151
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Inn & Suites Columbia Stadium Boulevard

Hilton Garden Inn Columbia

Hilton Garden Inn Columbia
3.0 star property
Columbia
8.6 out of 10, Excellent, (526)
"Nice quiet area to stay, clean rooms,"
United States
Vonda
Travelling for leisure
The price is AU$181
includes taxes & fees
10 Jan - 11 Jan 2026
Hilton Garden Inn Columbia

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
3.0 star property
Boonville
8.2 out of 10, Very good, (950)
"room was big and clean"
United States
Bridget
Travelling for leisure
The price is AU$147
includes taxes & fees
4 Jan - 5 Jan 2026
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Tru By Hilton Columbia South

Tru By Hilton Columbia South
2.5 star property
Columbia
The price is AU$178
includes taxes & fees
2 Jan - 3 Jan 2026
Tru By Hilton Columbia South

TownePlace Suites by Marriott Columbia

TownePlace Suites by Marriott Columbia
3.0 star property
Columbia
9.2 out of 10, Wonderful, (357)
"I really liked how quiet and safe the hotel felt."
United States
Madi
Travelling solo
The price is AU$186
includes taxes & fees
18 Jan - 19 Jan 2026
TownePlace Suites by Marriott Columbia

Courtyard by Marriott Columbia Missouri

Courtyard by Marriott Columbia Missouri
3.0 star property
Columbia
8.6 out of 10, Excellent, (665)
"The room and bathroom were very clean, spacious, and comfortable!!"
United States
Tiffany
Travelling with partner
The price is AU$171
includes taxes & fees
25 Jan - 26 Jan 2026
Courtyard by Marriott Columbia Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Prairie Home Hotel Reviews

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Frequently asked questions

What's the best place for a stay in Prairie Home?
Located 15.8 mi (25.4 km) from the heart of Prairie Home, Baymont by Wyndham Columbia, MO is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Stoney Creek Hotel Columbia and Wyndham Executive Center Columbia. See all available top hotels, or vacation rentals in Prairie Home.
What are some of the best holiday rentals that Prairie Home has to offer?
3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou: This holiday home rental outside of Prairie Home offers a patio, a garden and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, in addition to a kitchen with a fridge and a microwave. See all vacation rentals in Prairie Home.
If I need to cancel my hotel reservation in Prairie Home, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Prairie Home.
What's it like staying in Prairie Home?
Those travelling to Prairie Home will definitely enjoy the sights to see and things to do. There are 224 hotels and other accommodation options in the surrounding area. Find out more about Prairie Home.
What should I see while I'm in Prairie Home?
Places to visit in the wider area include Warm Springs Ranch, California Country Club and Isle of Capri Casino. You'll also find Rock Bridge Memorial State Park and Shelter Gardens in the area. Take a look at what more there is to see and do in Expedia's Prairie Home guide.
What's the seasonal weather like in Prairie Home?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 2°C. Average annual precipitation for Prairie Home is 1087 mm.

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