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Our top choices for Mousie hotels

Daniel Boone Motor Inn

Daniel Boone Motor Inn
2.5 star property
Pikeville
7.4 out of 10, Good, (383)
"Clean room big bed. "
United States
Anna
The price is AU$105
includes taxes & fees
1 Jan - 2 Jan 2026
Daniel Boone Motor Inn

Quality Inn & Suites Prestonsburg next to Mountain Arts Center

Quality Inn & Suites Prestonsburg next to Mountain Arts Center
2.5 star property
Prestonsburg
8.0 out of 10, Very good, (359)
"Nice clean place. Great rooms and price. Very friendly staff. "
United States
Jason
The price is AU$177
includes taxes & fees
1 Jan - 2 Jan 2026
Quality Inn & Suites Prestonsburg next to Mountain Arts Center

Comfort Suites Prestonsburg West

Comfort Suites Prestonsburg West
2.5 star property
Prestonsburg
8.6 out of 10, Excellent, (693)
"Room clean and staff just excellent!"
United States
Stephanie
The price is AU$171
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Prestonsburg West

Super 8 by Wyndham Prestonsburg

Super 8 by Wyndham Prestonsburg
2.0 star property
Prestonsburg
6.4 out of 10, (517)
"Friendly staff, clean room. "
United States
Heather
The price is AU$110
includes taxes & fees
26 Jan - 27 Jan 2026
Super 8 by Wyndham Prestonsburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place for a stay in Mousie?
Located 17.1 mi (27.5 km) from the heart of Mousie, Comfort Suites Prestonsburg West is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Quality Inn & Suites Prestonsburg next to Mountain Arts Center and Daniel Boone Motor Inn. See all available top hotels, or vacation rentals in Mousie.
What are some of the best holiday rentals that Mousie has to offer?
Kentucky's Majestic Mountaintop Estate with pool: The Bluegrass Palace: This holiday home rental outside of Mousie is located in the mountains, and has an indoor pool, a balcony and a BBQ to put you at ease in your new surroundings. It has 12 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. It offers a garden, an arcade/games room and 1 hot tub so that you can immerse yourself in your holiday. See all vacation rentals in Mousie.
If I need to cancel my hotel reservation in Mousie, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mousie.
What's it like to stay in Mousie?
Visitors will definitely enjoy all that Mousie has to offer. There are 19 hotels and other accommodation options in the surrounding area. Find out more about Mousie.
What is there to see in Mousie?
Places to visit in the wider area include Carr Creek State Park and Knott County Sportsplex. Take a look at what more there is to see and do in Expedia's Mousie guide.
What's the weather like in Mousie?
The hottest months are usually July and August, with an average temperature of 23°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Mousie is 1372 mm.

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