Search McClure hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for McClure hotels

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Rooms very clean and hotel next to a really good Chinese buffett."
United States
Melissa
Travelling for leisure
The price is AU$119
includes taxes & fees
21 Dec - 22 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
"Service for dinner and breakfast top notch."
United States
MICHAEL
Travelling for leisure
The price is AU$132
includes taxes & fees
23 Dec - 24 Dec
Drury Inn & Suites Jackson MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1001)
"Beds comfy and room clean"
United States
Jane
Travelling with family
The price is AU$161
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The downtown location was perfect for us."
United States
Deborah
The price is AU$198
includes taxes & fees
26 Dec - 27 Dec
Courtyard by Marriott Cape Girardeau Downtown

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
"The amenities were great, including the indoor pool and free popcorn."
United States
Mandy
Travelling with small children
The price is AU$153
includes taxes & fees
21 Dec - 22 Dec
Drury Plaza Hotel Cape Girardeau Conference Center

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (473)
"Overall I enjoyed my stay, besides my shower floor having feet prints everything else was pretty good."
United States
Ayana
Travelling for leisure
The price is AU$147
includes taxes & fees
18 Dec - 19 Dec
The Riverview

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Great room, free coffee and soda."
United States
Tara
Travelling for leisure
The price is AU$153
includes taxes & fees
23 Dec - 24 Dec
Drury Inn & Suites Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (669)
"Love the shower that is awesome."
United States
Joseph
The price is AU$137
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (784)
"the beds were actually very comfortable"
United States
Emily
Travelling with family
The price is AU$168
includes taxes & fees
23 Dec - 24 Dec
Hampton Inn Cape Girardeau I 55 East

Hotel 7 Inn Anna

Hotel 7 Inn Anna
2.5 star property
Anna
6.6 out of 10, (217)
"The staff was wonderful"
United States
Donna
The price is AU$143
includes taxes & fees
18 Dec - 19 Dec
Hotel 7 Inn Anna

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"The rooms are spacious and comfortable."
United States
Kristin
Travelling for leisure
The price is AU$119
includes taxes & fees
23 Dec - 24 Dec
Pear Tree Inn Cape Girardeau West

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Hotel was very clean and the lady that checked us in was very friendly."
United States
carla
Travelling for leisure
The price is AU$149
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (882)
"The room was clean and well appointed."
United States
Linda
Travelling for leisure
The price is AU$127
includes taxes & fees
11 Jan - 12 Jan 2026
Candlewood Suites Cape Girardeau by IHG

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (683)
"The area was safe & convenient to food"
United States
Sheri
Travelling with family
The price is AU$101
includes taxes & fees
1 Jan - 2 Jan 2026
Quality Inn Cape Girardeau North

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (102)
"The most impressive thing was the cleanliness throughout the whole property, not just the spotless rooms."
United States
Cassie
Travelling for leisure
The price is AU$149
includes taxes & fees
29 Dec - 30 Dec
Tru By Hilton Cape Girardeau

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is AU$235
includes taxes & fees
18 Dec - 19 Dec
Rockwood Inn

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very good, (739)
"Looking nice rooms were nice and clean."
United States
George
Travelling for leisure
The price is AU$130
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Jackson-Cape Girardeau

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (422)
"This hotel is located in a very good spot in Jackson Missouri is very clean."
United States
NAKEISHIA
Travelling with family
The price is AU$103
includes taxes & fees
16 Jan - 17 Jan 2026
Town House Inn

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"This is a unique place, having a kitchen and clean and spacious rooms, very comfortable"
United States
Larry
Travelling with partner
The price is AU$97
includes taxes & fees
11 Jan - 12 Jan 2026
Town House Inn Cape Giradreau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top McClure Hotel Reviews

Recent Reviews in McClure

More cheap accommodation in McClure

Frequently asked questions

What's the best place for a stay in McClure?
Located 8.2 mi (13.2 km) from the heart of McClure, Drury Plaza Hotel Cape Girardeau Conference Center is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are The Riverview and La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. See all available top hotels, or vacation rentals in McClure.
What are some of the best holiday rentals that McClure has to offer?
On the Wine Trail Hot Tub Wi-Fi : This holiday home rental outside of McClure is located on a lake, and has a patio, 1 hot tub and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in McClure.
If I need to cancel my hotel reservation in McClure, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in McClure.
What is staying in McClure like?
Those travelling to McClure will definitely enjoy the sights to see and things to do. There are 132 hotels and other accommodation options in the surrounding area. Find out more about McClure.
What is there to see in McClure?
A favourite place to visit is Devil's Island Wildlife Management Area. You'll also find Isle Casino Cape Girardeau and Show Me Center in the area. Take a look at what more there is to see and do in Expedia's McClure guide.
What's the seasonal weather like in McClure?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for McClure is 1491 mm.

Explore a world of travel with Expedia