The view of Manatee Springs and Suwannee River. Manatee Springs State Park is in Chiefland, Florida

Luxury Hotels & Resorts in Mayo from AU$61

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Check availability on Mayo Luxury Hotels

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Recommended hotels in Mayo

The Chalet On the Suwannee River

The Chalet On the Suwannee River
Mayo
10.0 out of 10, Exceptional, (1 review)
The price is AU$384
includes taxes & fees
21 June - 22 June
The Chalet On the Suwannee River

A-frame on the Suwannee River Rendezvous

A-frame on the Suwannee River Rendezvous
Mayo
6.0 out of 10, (1 review)
The price is AU$402
includes taxes & fees
21 June - 22 June
A-frame on the Suwannee River Rendezvous

The Best memories are made on the Suwannee River

The Best memories are made on the Suwannee River
Mayo
9.8 out of 10, Exceptional, (57 reviews)
The price is AU$402
includes taxes & fees
29 June - 30 June
The Best memories are made on the Suwannee River

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (135 reviews)
The price is AU$122
includes taxes & fees
21 June - 22 June
Cindys Motel

SpringHouse at Convict Springs

SpringHouse at Convict Springs
Mayo
The price is AU$198
includes taxes & fees
18 June - 19 June
SpringHouse at Convict Springs

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Mayo
10.0 out of 10, Exceptional, (12 reviews)
The price is AU$134
includes taxes & fees
19 June - 20 June
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.8 out of 10, Excellent, (32 reviews)
The price is AU$61
includes taxes & fees
22 June - 23 June
Suwannee River Rendezvous

RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house
Mayo
10.0 out of 10, Exceptional, (6 reviews)
The price is AU$114
includes taxes & fees
18 June - 19 June
RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo
10.0 out of 10, Exceptional, (13 reviews)
The price is AU$125
includes taxes & fees
23 June - 24 June
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Riverfront Cabin, Ichetucknee River

Riverfront Cabin, Ichetucknee River
Fort White
9.8 out of 10, Exceptional, (28 reviews)
The price is AU$1,043
includes taxes & fees
21 June - 22 June
Riverfront Cabin, Ichetucknee River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mayo Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Mayo holiday?
Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay special. If you want an upscale hotel with a spa, an indoor pool or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Mayo has to offer. Mayo has some interesting things to see and do including Lafayette Blue Springs State Park and Suwannee River, so you might want to take in the local sights during your visit.
When can I expect good weather in Mayo?
Planning for the weather is an important factor for making your trip to Mayo a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for Mayo is 1288 mm.
What's there to see and do in Mayo?
Enjoy Mayo and visit Lafayette Blue Springs State Park, Suwannee River and Perry Spring. If you have some spare time during your trip, you might want to check out Lafayette County Library and Veteran's Memorial Park of Mayo.

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