
Madre de Dios Region Holidays
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Your Madre de Dios Region Holiday
Choose one of our holiday packages to Madre de Dios Region and wander wherever your adventurous soul takes you. Hiking and nature are just a couple of the things you can look forward to in this wonderful destination. Start your trip to Madre de Dios Region by spending a few nights in Tambopata, one of the top cities here. Expedia has hotels, flights and all your other travel needs to help you curate your very own customised Madre de Dios Region holiday today.
Madre de Dios Region Essential Information
Language | Spanish |
|---|---|
Currency | Peruvian sols |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Padre Aldamiz Intl. Airport (PEM) |
Top Sights | Tambopata National Reserve, Sandoval Lake and Manu National Park |
Our pick of the best Madre de Dios Region Hotel Deals

Libelula Hotel
Jr Puno No. 429 Tambopata Madre de Dios
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (19 reviews)
Great stay, friendly owners and staff.
Reviewed on 22 June 2025

Inkaterra Reserva Amazonica
Madre De Dios River Km. 15 Las Piedras Madre de Dios
9.2/10 Wonderful! (43 reviews)
World class!
Reviewed on 19 Oct 2025

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Tambopata KM. 7 Otr. Carretera Bajo Tambopata Madre de Dios
The price is AU$238 per night from 11 Dec to 12 Dec
AU$238
11 Dec - 12 Dec
9/10 Wonderful! (6 reviews)
Half an hour a at from Puerto Maldonado by boat , the place is lovely, with river view and a feel of the jungle without venturing too far. We felt like we got a good insight into the area, with included excursions on the river and into the jungle. Our guide Yuri, who was with us throughout, was very ...
Reviewed on 23 Sept 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Madre de Dios Region
Manu National Park
Explore the great outdoors at Manu National Park, a lovely green space in Manu.
What to do in Madre de Dios Region

Puerto Maldonado: Kayak and Zip Line Adventure + Monkey Isla
AU$100
per adult

Puerto Maldonado: 4-Day Tambopata Rainforest Tour
AU$653
per adult

Puerto Maldonado |Hiking in the jungle + Sandoval Lake|
AU$108
per adult
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.












