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Check prices for these dates

Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov
In one month
11 Dec - 13 Dec
In two months
8 Jan - 10 Jan

Our top choices for La Mesa villas

An outdoor patio with a seating area, a grill, and a green wall.

1. Leyla| Pool/Spa|Downtown|Freeways|Beaches

Leyla| Pool/Spa|Downtown|Freeways|Beaches
Grant Hill
10.0 out of 10, Exceptional, (3 reviews)
"Everything was good, pool, spa, proximity to food and local frequent areas"
United States
Rob M.
The price is AU$623
includes taxes & fees
17 Nov - 18 Nov
Leyla| Pool/Spa|Downtown|Freeways|Beaches
An outdoor patio area with seating, a grill, and a decorative fence.

2. Bridge|Pool/Spa |Downtown|Freeways|Airport

Bridge|Pool/Spa |Downtown|Freeways|Airport
Grant Hill
10.0 out of 10, Exceptional, (3 reviews)
"The host was very helpful and accommodating. The place was excellent, and very close to downtown and the beaches that we wanted to visit.We will definitely stay at this place again next time we are in town."
United States
J C.
The price is AU$627
includes taxes & fees
17 Nov - 18 Nov
Bridge|Pool/Spa |Downtown|Freeways|Airport
A landscaped garden with a central fountain, stone benches, and a paved walkway leading to a green lawn.

3. Jamul's Jewel: 10ACRES,Hilltop,Heated*Salt Pool,Spa*,City & Mtn.Views,B-Ball Court*,Grill,Horseshoes

Jamul's Jewel: 10ACRES,Hilltop,Heated*Salt Pool,Spa*,City & Mtn.Views,B-Ball Court*,Grill,Horseshoes
Jamul
9.6 out of 10, Exceptional, (60 reviews)
"Great stay"
United States
Carson M.
The price is AU$598
includes taxes & fees
22 Nov - 23 Nov
Jamul's Jewel: 10ACRES,Hilltop,Heated*Salt Pool,Spa*,City & Mtn.Views,B-Ball Court*,Grill,Horseshoes
A two-story house with a garage, surrounded by palm trees and other vegetation.

4. Sleeps 50+ NEW Luxury Private Resort with Pool Golf Arcade Spa Playground Poker

Sleeps 50+ NEW Luxury Private Resort with Pool Golf Arcade Spa Playground Poker
Lakeside
10.0 out of 10, Exceptional, (17 reviews)
"Amazing property, host is very attentive, and overall a good experience !"
United States
Anthony S.
The price is AU$2,257
includes taxes & fees
16 Nov - 17 Nov
Sleeps 50+ NEW Luxury Private Resort with Pool Golf Arcade Spa Playground Poker
A swimming pool with inflatable flamingos and a covered area with string lights.

5. Luxury•PickleBall•Golf•Pool•HotTub•Grill•Arcades•6 TV’s•Playground• .5 Acre

Luxury•PickleBall•Golf•Pool•HotTub•Grill•Arcades•6 TV’s•Playground• .5 Acre
El Cajon
10.0 out of 10, Exceptional, (10 reviews)
"This place is an awesome vacation spot! The home is comfortable and the outdoor area is spectacular…even for a large group! Alvin is incredible to work with!"
United States
Sherri B.
The price is AU$1,678
includes taxes & fees
17 Nov - 18 Nov
Luxury•PickleBall•Golf•Pool•HotTub•Grill•Arcades•6 TV’s•Playground• .5 Acre
An outdoor pool area with a slide, seating, and umbrellas.

6. Resort-Style Villa with Pool & Spa

Resort-Style Villa with Pool & Spa
Rancho Bernardo
The price is AU$665
includes taxes & fees
24 Nov - 25 Nov
Resort-Style Villa with Pool & Spa
A modern house with a front entrance, a number '2552' on the wall, and a staircase leading up to the door.

7. 5-Units/26 guests/Heated Pool Option/Spa

5-Units/26 guests/Heated Pool Option/Spa
Grant Hill
The price is AU$3,086
includes taxes & fees
17 Nov - 18 Nov
5-Units/26 guests/Heated Pool Option/Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

See all hotels in La Mesa
A sunset over a mountainous landscape with scattered clouds.

Top reviews in La Mesa

A hotel with a covered outdoor area, palm trees, and a parking lot.
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
National City

10/10 Excellent

The room was very clean, the staff were very helpful. The location of the property was very good. Parking was excellent and we had great Wifi.
Australia
Clara
Reviewed September 29, 2026
Best Western Plus Marina Gateway Hotel

Frequently Asked Questions

How much do villas in La Mesa cost?

Villas in La Mesa cost between AU$598 and AU$3,085 per night. These stays give you the privacy to enjoy your own space at a price that's easy on your wallet. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What is there to do near my villa in La Mesa?

You'll find loads of superb things to fill your itinerary with in La Mesa. You won't want to miss major attractions like San Diego Zoo, San Diego Civic Theatre and San Diego Natural History Museum. San Diego Air and Space Museum, San Diego Museum of Art and New Childrens Museum also appeal to many visitors.