Isle of Palms Hotels, Jacksonville

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Our top choices for Isle of Palms hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (493 reviews)
"Location was very perfect for an appointment at The Mayo Clinic. Staff could not have been nicer."
United States
Jill
The price is AU$218
includes taxes & fees
8 May - 9 May
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.9 km from Isle of Palms
8.8 out of 10, Excellent, (1,000 reviews)
"Safe and comfortable stay"
United States
Kylie
The price is AU$163
includes taxes & fees
31 May - 1 June
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
30.8 km from Isle of Palms
8.8 out of 10, Excellent, (385 reviews)
"Staff was very friendly!"
United States
Dawn
The price is AU$128
includes taxes & fees
4 May - 5 May
Extended Stay America Premier Suites - Jacksonville - Airport

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.4 km from Isle of Palms
9.2 out of 10, Wonderful, (319 reviews)
"Close to airport and nice modern facility."
United States
Cheryl
The price is AU$212
includes taxes & fees
10 May - 11 May
Home2 Suites By Hilton Jacksonville Downtown

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.3 km from Isle of Palms
7.6 out of 10, Good, (462 reviews)
"The property was very clean and the staff was very nice. Breakfast was delicious "
United States
Jose
The price is AU$122
includes taxes & fees
4 May - 5 May
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (217 reviews)
"The staff and the location are great. "
United States
Jorge Miguel
The price is AU$257
includes taxes & fees
9 May - 10 May
Hilton Jacksonville At Mayo Clinic

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,078 reviews)
"Breakfast is pretty good for a hotel. "
United States
David
The price is AU$213
includes taxes & fees
25 May - 26 May
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.7 km from Isle of Palms
8.8 out of 10, Excellent, (683 reviews)
"We had an excellent stay. The staff were very friendly and accommodating. "
United States
Courtney
The price is AU$257
includes taxes & fees
4 May - 5 May
Seahorse Oceanfront Inn

Tru by Hilton Jacksonville Airport I-95

Tru by Hilton Jacksonville Airport I-95
2.5 star property
31.5 km from Isle of Palms
9.4 out of 10, Exceptional, (1,047 reviews)
"The property was nice, clean, safe and the room was extremely well kept."
United States
Lisa Nannette
The price is AU$136
includes taxes & fees
11 May - 12 May
Tru by Hilton Jacksonville Airport I-95

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (3,896 reviews)
"Great location for beach access and walkable to restaurants "
United States
Kelly
The price is AU$268
includes taxes & fees
6 May - 7 May
Margaritaville Jacksonville Beach

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
5 km from Isle of Palms
8.4 out of 10, Very good, (1,003 reviews)
"Great location and friendly staff. "
United States
Harry
The price is AU$273
includes taxes & fees
10 May - 11 May
Courtyard by Marriott Jacksonville Beach Oceanfront

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,002 reviews)
"Staff was incredibly friendly, breakfast was great, nice location."
United States
Melissa
The price is AU$172
includes taxes & fees
13 May - 14 May
Holiday Inn Express Jacksonville - Blount Island by IHG

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,000 reviews)
"Great stay with the family."
United States
Ivan
The price is AU$218
includes taxes & fees
10 May - 11 May
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.4 km from Isle of Palms
7.4 out of 10, Good, (1,002 reviews)
"The staff at this hotel were very friendly and accommodating. The room was comfortable and very clean, though the curtain was short and allowed a lot of sunlight in at sunup."
United States
Josie
The price is AU$112
includes taxes & fees
5 May - 6 May
Wingate by Wyndham Jacksonville FL

Weekly Inn

Weekly Inn
2.0 star property
14.9 km from Isle of Palms
7.6 out of 10, Good, (1,246 reviews)
"Thank you for the stay the room was clean and quiet and comfortable. Thanks for the stay"
United States
Bobbi
The price is AU$77
includes taxes & fees
3 May - 4 May
Weekly Inn

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,006 reviews)
"Very convenient to the beach and short walk to restaurants. "
United States
Michelle
The price is AU$219
includes taxes & fees
3 May - 4 May
Best Western Oceanfront

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
18.5 km from Isle of Palms
9.0 out of 10, Wonderful, (1,002 reviews)
"newly renovated. quite clean, quiet location and good continental breakfast. "
United States
katie
The price is AU$154
includes taxes & fees
1 June - 2 June
Hampton Inn & Suites Jacksonville South - Bartram Park

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
3 km from Isle of Palms
9.2 out of 10, Wonderful, (607 reviews)
"Clean room, great staff, decent breakfast, service animal friendly "
United States
Joseph
The price is AU$173
includes taxes & fees
10 May - 11 May
TownePlace Suites by Marriott Jacksonville East

Home2 Suites by Hilton Jacksonville Airport

Home2 Suites by Hilton Jacksonville Airport
3.0 star property
31.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,006 reviews)
"The breakfast was excellent. Room clean, staff kind and helpful."
United States
Mariangelys
The price is AU$159
includes taxes & fees
4 May - 5 May
Home2 Suites by Hilton Jacksonville Airport

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
31.1 km from Isle of Palms
9.0 out of 10, Wonderful, (2,479 reviews)
"Clean room, staff was nice. Super close the airport to fly out early."
United States
Jon
The price is AU$192
includes taxes & fees
16 May - 17 May
Hyatt Place Jacksonville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on our traveller data, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is one of the top choices for your stay in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 42 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.

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