Isle of Palms Holidays
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Your Isle of Palms Holiday
Your next big adventure beckons with a holiday package to Isle of Palms. Food, fun and nothing but good times — you're bound to find it in this neighbourhood. Not sure what to do during your trip to Isle of Palms? Nearby attractions like Jacksonville Beach Pier, Oceanfront Park and Adventure Landing are good places to start. Expedia can put your plans into action. Book your dream Isle of Palms holiday today.
Our guide on where to stay in Isle of Palms
Find the best Isle of Palms areas and neighborhoods for the activities you enjoy most. Learn more about Isle of Palms
Amelia City
While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.
Oceanfront
While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.
Downtown Jacksonville
2 out of top 10 points of interest in this area
The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.
Southside
1 out of top 10 points of interest in this area
If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.
Sawgrass
Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.
Our pick of the best Isle of Palms Hotel Deals
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
4905 SAN PABLO ROAD SOUTH Jacksonville FL
Fully refundableReserve now, pay when you stay
AU$222
2 Oct - 3 Oct
includes taxes & fees
9.4/10 Exceptional! (592 reviews)
"The staff were very friendly and helpful."
Reviewed on 31 Aug 2026
Margaritaville Jacksonville Beach
715 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
AU$236
3 Sept - 4 Sept
includes taxes & fees
Hyatt Regency Jacksonville
225 E Coastline Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
AU$266
8 Sept - 9 Sept
includes taxes & fees
9/10 Wonderful! (1,788 reviews)
"Musty smell in rooms. A lot of people complaining about it"
Reviewed on 1 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does an Isle of Palms holiday package cost?
Starting from as low as , you can build your own Isle of Palms holiday package. Simply bundle flights, hotels and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Isle of Palms?
If you love getting a great deal, bundle your bookings into an Isle of Palms holiday package. Whether you need hotels, flights, day tours or rental cars, you can book them all in one place. You'll have ample choice at your fingertips too. Expedia has over 550 air carriers and 1 000 000 hotels all over the world to take your pick of. Fly with who you prefer, stay wherever you like and save precious money — now that's the ideal escape!
Where should I stay in Isle of Palms?
Make sightseeing a breeze by staying someplace right around the corner from Isle of Palms's big attractions. St. Johns Town Centre and University of North Florida are two traveller favourites.
What are the top hotels in Isle of Palms?
Get your trip off to a great start by locking in a room at The Retreat Close To Mayo Clinic. It's one of most sought-after hotels in Isle of Palms. Another top option is Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How far in advance should I book my Isle of Palms holiday?
Your best bet is to book early. Airlines usually advertise flights nearly 12 months prior to departure, and this is a perfect opportunity to land some of the lowest prices. Boss just told you to take your holiday time next week? No sweat. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Isle of Palms travel package include?
From hotels and flights to car rentals, Expedia can help you shape an Isle of Palms package that's perfect for you. Holidaying for a while? Look into a rental car, flight and hotel bundle. If you can only squeeze in a quick getaway, a hotel and airfare deal could suit you better. Experiences can also be added once you've made your booking. Our holiday packages make it a breeze to save and plan.
What should I know before booking an Isle of Palms travel package?
A travel package can be easier on the hip pocket than individually booking everything you need for your adventure. For example, bundle your hotels, flights and rental cars and save a pretty penny. Whatever sort of holiday you're planning, there's sure to be a package that matches your budget.
Can I choose my airline with an Isle of Palms Expedia holiday package?
Yes, the choice is all yours. We have access to over 550 partner airlines throughout the world, so you can design your Isle of Palms trip according to your travel needs.
If I'm not able to travel, can I cancel my Isle of Palms holiday package?
Because we understand life is full of surprises, the answer is yes. To find out more, check out our Customer Service Portal. But generally speaking, if you've booked your package in the last 24 hours, you may be able to cancel or change it with no penalties. Your airline, hotel or car rental company may charge a fee if your booking is older than that.
Activities
The Escape Game at St. John's Town Center in Jacksonville
AU$58
per adult
100% of travellers recommend
St. Augustine: St. Johns River Airboat Safari with a Guide
AU$73
per adult
100% of travellers recommend
CraigCat Boat Tour from Fernandina Beach
AU$202
per adult
98% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.