Santo Spirito Travel Guide

Tourist Guide

Santo Spirito
Santo Spirito
Santo Spirito
Santo Spirito
Santo Spirito

Popular places to visit

Piazza Santo Spirito

Piazza Santo Spirito

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and notable monuments in this vibrant area.

Piazza Santo Spirito
Porta Romana

Porta Romana

Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.

Porta Romana
Brancacci Chapel

Brancacci Chapel

A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.

Brancacci Chapel

Santo Spirito Basilica

Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.

Santo Spirito Basilica

Santa Maria della Carmine

You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area.

Santa Maria della Carmine

Piazza del Carmine

You can learn about the history of Florence with a trip to Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art galleries.

Piazza del Carmine

Activities

Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

AU$37
per adult
76% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Pisa and Cinque Terre Day Trip from Florence

Cinque Terre and Pisa Day Trip from Florence

AU$159
per adult
94% of travellers recommend
Cinque Terre and Pisa Day Trip from Florence
Best of Florence Walking Tour

Best of Florence Walking Tour

AU$36
per adult
100% of travellers recommend
Best of Florence Walking Tour
Florence half day combo tour with David, Uffizi & Duomo

Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia

AU$73
per adult
90% of travellers recommend
Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia
Florence: Palazzo Vecchio Guided Tour

Florence: Palazzo Vecchio Guided Tour

AU$39
per adult
Florence: Palazzo Vecchio Guided Tour
Florence: Reserved Entry Ticket to Bargello Museum

Florence: Reserved Entry Ticket to Bargello Museum

AU$29
per adult
Florence: Reserved Entry Ticket to Bargello Museum
See all activities in Florence

Our pick of the best Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13, Florence, FI
The price is AU$279 per night from 3 Nov to 4 Nov
AU$279
3 Nov - 4 Nov
includes taxes & fees
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (568 reviews)
"I thought it was great but the wife didn’t think it was completely worthy of 5 stars. She’s hard to please."

Reviewed on 30 Sept 2025

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,033 reviews)
"The apartment is beautiful, quite large (especially by European standards), very clean, and centrally located in the Santo Spirito, and only about a 5-minute walk to Ponte Vecchio. The people at reception were all very friendly and helpful. We would definitely stay here again when in Florence."

Reviewed on 30 Sept 2025

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Palazzo Mannaioni Suites
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59, Florence, FI
The price is AU$345 per night from 19 Oct to 20 Oct
AU$345
19 Oct - 20 Oct
includes taxes & fees
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (987 reviews)
"Amazing place, love the decor!"

Reviewed on 28 July 2025

UNA Hotels Vittoria Firenze
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8, Florence, FI
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...
9/10 Wonderful! (211 reviews)
"Beautiful hotel in a great location! Staff was super friendly and helpful and the price is a bargain compared to some other hotels. We had a great experience!"

Reviewed on 25 Sept 2025

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La Torre Del Cestello
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Piazza del Carmine, 21, Florence, FI
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (329 reviews)
"Solo woman traveler here. Felt very safe. Loved the convenience and options of breakfast every morning. The garden is lovely and wished I had spent more time there. The room was nothing fancy, but my time there was great. Thankfully nobody was staying next door to my room because the last night I ..."

Reviewed on 26 Sept 2025

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Casa Santo Nome di Gesù
Hotel Firenze 2000

Hotel Firenze 2000

2 out of 5
Viale Raffaello Sanzio, 16, Florence, FI
The price is AU$140 per night from 6 Nov to 7 Nov
AU$140
6 Nov - 7 Nov
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Popular attractions Ponte Vecchio and Uffizi Gallery are located ...
7.2/10 Good! (179 reviews)
"This is definitely a budget hotel. For what we paid, we received excellent value and service. The rooms were clean (though minimal) - cleaned daily with fresh towels, the staff all very helpful, the breakfast more than adequate, and even though the walk to the downtown core a bit further, (25 min ..."

Reviewed on 3 Oct 2025

Hotel Firenze 2000
See all 473 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santo Spirito

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San Frediano

San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Santo Spirito Basilica while you're in town.

San Frediano
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Oltrarno

4.5/5(22 area reviews)

Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood.

Oltrarno
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Santa Maria Novella

4.5/5(108 area reviews)

Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

San Giovanni
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Duomo

4.5/5(143 area reviews)

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.

Duomo
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Historic Centre of Florence

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Historic Centre of Florence

Santo Spirito Travel Guide

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