Santo Spirito Travel Guide
Tourist Guide
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and stunning cathedral in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the acclaimed art galleries and churches in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Piazza del Carmine
You can learn about the history of Florence with a trip to Piazza del Carmine. Amble around this vibrant area's riverfront or experience its fascinating museums.
Activities
City Sightseeing Florence Hop-on Hop-off Bus Tour
Florence: Pisa Tour through Tuscan Hills & Optional Tower Entry
Small-Group Wine Tasting Experience in the Tuscan Countryside
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
From Florence: Siena, San Gimignano, Pisa, Chianti Tour with Lunch & Wine
Our pick of the best Santo Spirito Hotel Deals
Hotel Horto Convento
Great hotel all around and great breakfast. Highly recommend and will go back when in Florence
Reviewed on 19 Apr 2026
Palazzo Mannaioni Suites
Great location. Clean room. Great staff.
Reviewed on 22 Apr 2026
La Torre Del Cestello
The room was not at all as shown. The hotel lobby isn’t a lobby but a small room with a check in desk on the 3 floor. There is only a few rooms. This is not a hotel. The cafe/bar on the lower level is loud with extremely loud music and they go until 4 am. We could not sleep. The main chandelier in ...
Reviewed on 20 Apr 2026
UNA Hotels Vittoria Firenze
Helpful staff. Vey good breakfast. Clean and comfortable room.
Reviewed on 1 Apr 2026
Foresteria Valdese di Firenze - Casa per Ferie
The staff was amazing.
Reviewed on 10 Apr 2026
Palazzo Oliveto
The room was not that clean, there was mold on the shower, there were some stains on the wall. The higienic part of the overall room is the reason why I give 2.
Reviewed on 10 Nov 2025
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Santo Spirito Basilica while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Pitti Vintage while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.
