Santo Spirito Travel Guide
Tourist Guide
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and stunning cathedral in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the acclaimed art galleries and churches in this vibrant area.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the stunning cathedral and notable monuments in this vibrant area.
Activities
City Sightseeing Florence Hop-on Hop-off Bus Tour
Small-Group Wine Tasting Experience in the Tuscan Countryside
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
Our pick of the best Santo Spirito Hotel Deals
Hotel Horto Convento
"We booked our stay at Hotel Horto Convento, but were moved to their newer sister hotel,"
Reviewed on 5 June 2026
Palazzo Mannaioni Suites
"Clean, spacious room. Wonderful location, couldn’t ask for more - highly recommended"
Reviewed on 3 June 2026
La Torre Del Cestello
"Central city location"
Reviewed on 9 June 2026
UNA Hotels Vittoria Firenze
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"
Reviewed on 12 May 2026
Torre di Bellosguardo
"This was by far the best hotel I have ever stayed at, as someone who travels solo often sometimes you are just looking for some peace and not having to do everything on your own. I am in awe of the property. If you are looking for privacy, story book views, and gardens this is the place to be. The ..."
Reviewed on 29 Oct 2025
Foresteria Valdese di Firenze - Casa per Ferie
"We loved our stay here! The area was nice and quiet, but still had plenty to do and eat. The room was lovely, with gorgeous high ceilings."
Reviewed on 10 June 2026
Our guide on where to stay in Santo Spirito
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Piazza della Signoria are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.
San Giovanni
If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.
