Find LGBTQ welcoming hotels in Florence, SC

Tue, 21 Oct: Check-in selected.
To Date
Wed, 22 Oct: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Top Florence LGBT Welcoming Hotels

Home2 Suites by Hilton Florence, SC
3 out of 5
900 Woody Jones Blvd, Florence, SC
The price is AU$179 per night from 26 Oct to 27 Oct
AU$179
26 Oct - 27 Oct
includes taxes & fees
8.2/10 Very Good! (1,000 reviews)
"Nice quick overnight on long distance trip"

Reviewed on 27 Sept 2025

Opens in a new windowHome2 Suites by Hilton Florence, SC
Tru by Hilton Florence I-95
2.5 out of 5
2140 West Lucas Street, Florence, SC
Fully refundableReserve now, pay when you stay
The price is AU$169 per night from 2 Nov to 3 Nov
AU$169
2 Nov - 3 Nov
includes taxes & fees
8.2/10 Very Good! (1,001 reviews)
"No frills, great place (as is all TRU by Hilton) to stop overnight on road trips. The free breakfast is a plus. Like the Not Soap Radio products."

Reviewed on 26 Sept 2025

Opens in a new windowTru by Hilton Florence I-95
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 out of 5
2101 Florence Harllee Blvd, Florence, SC
Fully refundable
The price is AU$181 per night from 13 Oct to 14 Oct
AU$181
13 Oct - 14 Oct
includes taxes & fees
8.4/10 Very Good! (1,008 reviews)
"Perfect next from Bucee"

Reviewed on 3 Oct 2025

Opens in a new windowHoliday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Save an average of 15% on thousands of hotels when you're signed in
Hampton Inn & Suites Florence-North-I-95
2.5 out of 5
1735 Stokes Road, Florence, SC
Fully refundableReserve now, pay when you stay
The price is AU$179 per night from 21 Oct to 22 Oct
AU$179
21 Oct - 22 Oct
includes taxes & fees
8.8/10 Excellent! (748 reviews)
"Hot tub and pool were great! Comforters/sheets on bed need upgrading….they’re not very cozy. Hotel lobby and breakfast areas nice looking."

Reviewed on 1 Oct 2025

Opens in a new windowHampton Inn & Suites Florence-North-I-95
Staybridge Suites Florence - Civic Center by IHG
3 out of 5
150 Westpark Drive, Florence, SC
Fully refundable
The price is AU$228 per night from 12 Oct to 13 Oct
AU$228
12 Oct - 13 Oct
includes taxes & fees
9.4/10 Exceptional! (901 reviews)
"Everything was very clean, staff was very helpful, and the breakfast was amazing."

Reviewed on 2 Oct 2025

Opens in a new windowStaybridge Suites Florence - Civic Center by IHG
Homewood Suites by Hilton Florence
3 out of 5
3450 W Radio Drive, Florence, SC
Fully refundableReserve now, pay when you stay
The price is AU$206 per night from 2 Nov to 3 Nov
AU$206
2 Nov - 3 Nov
includes taxes & fees
8.2/10 Very Good! (644 reviews)
"Good location, friendly staff, clean room."

Reviewed on 3 Oct 2025

Opens in a new windowHomewood Suites by Hilton Florence
Red Roof Inn Florence - Civic Center
2 out of 5
2690 David H McLeod Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
The price is AU$95 per night from 12 Oct to 13 Oct
AU$95
12 Oct - 13 Oct
includes taxes & fees
6.6/10 (1,001 reviews)
"Nice"

Reviewed on 1 Oct 2025

Opens in a new windowRed Roof Inn Florence - Civic Center
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 out of 5
3440 W Radio Dr, Florence, SC
Fully refundable
The price is AU$188 per night from 12 Oct to 13 Oct
AU$188
12 Oct - 13 Oct
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
"hotel is Great if U like Dogs, had a doggy bad smell."

Reviewed on 27 Sept 2025

Opens in a new windowHoliday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Courtyard by Marriott Florence
3 out of 5
2680 Hospitality Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
The price is AU$164 per night from 19 Oct to 20 Oct
AU$164
19 Oct - 20 Oct
includes taxes & fees
7.8/10 Good! (677 reviews)
"Clean and firm comfortable bed. Excellent flatbread from the restaurant and a good size menu of options."

Reviewed on 29 Sept 2025

Opens in a new windowCourtyard by Marriott Florence
TownePlace Suites by Marriott Florence
3 out of 5
2650 Hospitality Boulevard, Florence, SC
Fully refundableReserve now, pay when you stay
The price is AU$175 per night from 12 Oct to 13 Oct
AU$175
12 Oct - 13 Oct
includes taxes & fees
8.8/10 Excellent! (661 reviews)
"The staff was real friendly (Hanna). She welcomed us and made us feel right at home....another staff member was nice but I didn't get her name..."

Reviewed on 2 Oct 2025

Opens in a new windowTownePlace Suites by Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Enjoy gay-friendly hotels in Florence


What kinds of gay-friendly hotels are there in Florence?


When you're looking for gay-friendly hotels in Florence, you'll find a wide variety of options to choose from. These welcoming hotels come in all shapes and sizes and offer a diverse array of amenities and special features you can enjoy. Whether you're looking for something romantic, like hotels with spa facilities, or are more interested in rooms better fit for a solo traveller or a group of friends, you'll find it here. What these hotels all have in common, though, is strict anti-discrimination policies and insight into some of the most popular LGBTQ-friendly activities available in town.


What are the best gay-friendly hotels in Florence like?


The best gay-friendly hotel in Florence depends on what you're looking for in accommodation. Fortunately, you can easily find what you need, thanks to the multitude of available search filters. You can filter based on amenities you may be interested in, like hot tubs or pet-friendly policies, or you can sort by star rating. You can even filter by guest reviews to show only hotels that have received predominantly high marks from previous guests. Don't forget to mark the filter for LGBTQ-friendly hotels to only show anti-discriminatory hotels in your results.


How can I find deals on Florence gay-friendly hotels?


You'll find plenty of deals on gay-friendly hotels in Florence. If you want to increase your chances of finding a deal, try booking your stay in the off-season when prices are usually cheaper. Additionally, think about what amenities you may be willing to go without to drive the price down even further. Of course, booking a short distance away from prominent attractions can be an easy way to save while still being close to public transport routes that can get you to the action easily. Just keep in mind that these are general trends rather than solid rules, as prices fluctuate all the time and can be difficult to predict.


Why should I book a gay-friendly hotel in Florence with Expedia?


Booking with Expedia makes your holiday planning easier than ever before. Not only will you be able to enjoy a massive selection of gay-friendly hotels in Florence, but you can also book a flight as well. In fact, booking both through Expedia may even unlock some additional savings. Plus, you can take advantage of the Expedia Rewards program. Joining is completely free, and every booking earns you points that you can redeem later for additional discounts. Plus, you'll enjoy deep discounts on certain hotels simply by being a member.


Are gay-friendly hotels in Florence fully refundable?


A fully refundable cancelation is a handy feature to have, and numerous gay-friendly hotels in Florence offer it. Expedia is proud to host a wide variety of hotels that offer full refund – there's even a search-filter option for it. You'll be able to see all qualifying hotels clearly marked on your search results page without even having to click the hotels individually.

More ways to book

More ways to book