East Main Street Hotels, Grand Junction

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Our top choices for East Main Street hotels

Dtwn Walkability! Grand Junction Couple's Retreat

Dtwn Walkability! Grand Junction Couple's Retreat
3.0 star property
East Main Street
10.0 out of 10, Exceptional, (3 reviews)
"Our stay was fantastic! The location was perfect—close to everything. The property was clean and loved the decor. The host was super responsive and helpful, making our trip stress-free. Highly recommend!"
United States
renee
The price is AU$364
includes taxes & fees
10 May - 11 May
Dtwn Walkability! Grand Junction Couple's Retreat

Balanced Rock Inn

Balanced Rock Inn
3.0 star property
19 km from East Main Street
9.0 out of 10, Wonderful, (53 reviews)
"Clean room, easy parking and check-in. "
United States
Andriette
The price is AU$231
includes taxes & fees
4 May - 5 May
Balanced Rock Inn

Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
2.5 star property
8.7 km from East Main Street
8.8 out of 10, Excellent, (848 reviews)
"Nice pool and hot tub Nice breakfast Rooms were clean and nice"
United States
Jack
The price is AU$174
includes taxes & fees
18 May - 19 May
Best Western Grande River Inn & Suites

Super 8 by Wyndham Fruita

Super 8 by Wyndham Fruita
2.0 star property
18.6 km from East Main Street
8.4 out of 10, Very good, (1,002 reviews)
"Staff very helpful, very good breakfast."
United States
Don
The price is AU$149
includes taxes & fees
3 May - 4 May
Super 8 by Wyndham Fruita

Wine Country Inn Palisade

Wine Country Inn Palisade
3.5 star property
17.1 km from East Main Street
9.6 out of 10, Exceptional, (1,008 reviews)
"Wonderful place to stay. When visiting our daughter again this will be our place to stay. "
United States
David
The price is AU$262
includes taxes & fees
3 May - 4 May
Wine Country Inn Palisade

The Homestead

The Homestead
4.5 star property
20.4 km from East Main Street
10.0 out of 10, Exceptional, (70 reviews)
"Very nicely renovated motel! Clean, comfortable beds, small fridge, microwave, coffee and ice maker. Outdoor sitting area with beautiful views of nearby red rock cliffs. Owners friendly and responsive. Highly recommended if you’re staying in beautiful Palisade!"
United States
Julia
The price is AU$314
includes taxes & fees
3 May - 4 May
The Homestead

Spoke and Vine Motel

Spoke and Vine Motel
2.5 star property
17.4 km from East Main Street
9.8 out of 10, Exceptional, (169 reviews)
"What a great hotel! They have done a fantastic job with upgrades to the rooms and facilities. The staff was super friendly. Highly recommend this hidden gem. "
United States
Russ
The price is AU$236
includes taxes & fees
4 May - 5 May
Spoke and Vine Motel

Grand Vista Hotel

Grand Vista Hotel
3.5 star property
Horizon Drive District, 5.5 km from East Main Street
8.2 out of 10, Very good, (3,633 reviews)
"Great place to stay. "
United States
Hannah Or Nathan
The price is AU$147
includes taxes & fees
5 May - 6 May
Grand Vista Hotel

Castle Creek B&B

Castle Creek B&B
3.5 star property
3.4 km from East Main Street
9.8 out of 10, Exceptional, (217 reviews)
"This was a lovely B&B! Brenda was very welcoming. Our room was super cute. Brenda made a delicious breakfast! Very relaxing stay."
United States
Mary
The price is AU$241
includes taxes & fees
3 May - 4 May
Castle Creek B&B

The Hotel Melrose

The Hotel Melrose
2.0 star property
Historic Grand Junction, 1.3 km from East Main Street
9.2 out of 10, Wonderful, (146 reviews)
"Great little hotel location is great for wandering on foot on downtown Junction."
United States
Jeffrey
The price is AU$218
includes taxes & fees
18 May - 19 May
The Hotel Melrose

Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
3.0 star property
Horizon Drive District, 4.9 km from East Main Street
8.6 out of 10, Excellent, (1,000 reviews)
"Great value and perfect for our business trip."
United States
Damon
The price is AU$167
includes taxes & fees
5 May - 6 May
Quality Inn Grand Junction near University

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 5.4 km from East Main Street
8.8 out of 10, Excellent, (2,850 reviews)
"yes Breakfast perfect, parking great staff was amazing"
United States
joseph
The price is AU$237
includes taxes & fees
4 May - 5 May
La Quinta Inn & Suites by Wyndham Grand Junction

Red Roof Inn Grand Junction

Red Roof Inn Grand Junction
2.0 star property
9.2 km from East Main Street
6.8 out of 10, (1,000 reviews)
"everything is good"
United States
Kantemir
The price is AU$100
includes taxes & fees
17 May - 18 May
Red Roof Inn Grand Junction

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
2.5 star property
Historic Grand Junction, 1.4 km from East Main Street
9.2 out of 10, Wonderful, (1,004 reviews)
"Great breakfast nice staff"
United States
Erin
The price is AU$233
includes taxes & fees
18 May - 19 May
Tru by Hilton Grand Junction Downtown

Bark And Bike Abode 3 Bedroom Home

Bark And Bike Abode 3 Bedroom Home
3.0 star property
17.3 km from East Main Street
The price is AU$822
includes taxes & fees
4 May - 5 May
Bark And Bike Abode 3 Bedroom Home

Comfort Inn & Suites Fruita - Grand Junction

Comfort Inn & Suites Fruita - Grand Junction
2.5 star property
18.5 km from East Main Street
8.4 out of 10, Very good, (1,000 reviews)
"My family and I stopped in for a night as we were passing through town, we really enjoyed our stay, the breakfast and service was amazing."
United States
Joel
The price is AU$167
includes taxes & fees
26 May - 27 May
Comfort Inn & Suites Fruita - Grand Junction

Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.2 out of 10, Very good, (1,914 reviews)
"Quiet, comfortable bed, good breakfast."
United States
Tammy
The price is AU$139
includes taxes & fees
25 May - 26 May
Ramada by Wyndham Grand Junction

Camp Eddy

Camp Eddy
1.0 star property
Pear Park, 1.5 km from East Main Street
9.4 out of 10, Exceptional, (322 reviews)
"Great stay"
United States
Theodore
The price is AU$206
includes taxes & fees
3 May - 4 May
Camp Eddy

Home2 Suites by Hilton Grand Junction Northwest

Home2 Suites by Hilton Grand Junction Northwest
3.0 star property
24 Road Corridor, 5.8 km from East Main Street
9.2 out of 10, Wonderful, (940 reviews)
"Clean, comfortable, and very helpful front desk!"
United States
Kim
The price is AU$268
includes taxes & fees
1 June - 2 June
Home2 Suites by Hilton Grand Junction Northwest

Hotel Maverick

Hotel Maverick
4.0 star property
Capitol Hill, 1.6 km from East Main Street
9.6 out of 10, Exceptional, (1,001 reviews)
"Centrally located, very clean, great restaurant."
United States
Danielle
The price is AU$312
includes taxes & fees
25 May - 26 May
Hotel Maverick
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in East Main Street

Find the best East Main Street areas for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

Though Downtown may not have many top sights, you can venture to the surrounding area to see attractions like Western Colorado Botanical Gardens and Bananas Fun Park.

Pear Park

While visiting Pear Park, you might make a stop by sights like Colorado River and James M. Robb – Colorado River State Park.

Historic Grand Junction

Visitors highly recommend Historic Grand Junction for its abundant dining options, and you can make a stop by Museum of the West while you're in town.

Horizon Drive District

Horizon Drive District might not have many top sights, but Canyon View Park and Bananas Fun Park are two attractions nearby that you can check out.

Top East Main Street Hotel Reviews

Frequently asked questions

What's it like in East Main Street?
Travellers will be sure to enjoy their time in Grand Junction's East Main Street neighbourhood.
Where is the best hotel for a stay in East Main Street?
For your stay in East Main Street, Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars. is one of the top choices based on our traveller data. Other good choices for your stay in the area include Dtwn Walkability! Grand Junction Couple's Retreat and Launch your Colorado adventures – Historic Downtown convenience.
How many hotels can I expect to find in the East Main Street area?
If you're searching for places to stay in Grand Junction, Expedia has something to meet your needs with 24 East Main Street hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in East Main Street, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best deals in East Main Street.
What is there to do around this Grand Junction neighbourhood?
A few places to visit in the area around East Main Street include Museum of the West, Western Colorado Botanical Gardens and Elliott Tennis Center. While you're out sightseeing, Western Colorado Center for the Arts and Tennis Junction Indoor Center are a couple of additional sights to visit in Grand Junction.